PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBE2NL MEPCE 17643375 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VCAM1 UBE2NL 22623428 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ITGA4 UBE2NL 22623428 biogrid exp G G G G PHGDH UBE2NL 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CNOT4 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF135 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF215 23023127 pred G G G G G G G G G G G UBE2H UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2D4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF150 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF39 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF39 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM17 23023127 pred G RING1 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBTD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF169 23023127 pred UBE2V2 UBE2NL 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO2 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF32 23023127 pred G UBE2NL UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBQLN3 23023127 pred G G G G G G G G UBE2D1 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF115 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2L6 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF151 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G UBE2NL ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RLIM 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM58 23023127 pred G G G G UBE2E1 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TP53 UBE2NL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2J2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2N UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBX1 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2C UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2T 23023127 pred G G G G G G G G G G G G G UBE2NL UBL7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2K UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBTD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL FAF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF103 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEDD8 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2B UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM22 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RCHY1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRKCG UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G SUMO1 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM37 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF183 23023127 pred G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM65 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL NSFL1C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL SUMO4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM48 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G UBE2G2 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF113B 23023127 pred SLC2A4 UBE2NL 25402006 pred UBE2NL ZNRF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL ZNRF2 23023127 pred G G G G G G G G G G G G G G G G G G RAG1 UBE2NL 23023127 pred CBLB UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL AKTIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UHRF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL STUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAD23A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TMEM189 UBE2NL 25402006 pred UBE2D2 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBC UBE2NL 23023127 pred UBE2NL RFPL4B 23023127 pred UBE2NL UBA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF175 23023127 pred G G G G G G G G G G G G G G G G G UBE2S UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2G1 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CBL UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM64B UBE2NL 23023127 pred DLG4 UBE2NL 25402006 pred G G G G G G G G G G G G G G G UBE3A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBL4A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2U 23023127 pred G UBE2NL PRPF19 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RBBP6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF123 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D3 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDC34 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RIPK2 UBE2NL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G XIAP UBE2NL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF2 UBE2NL 25402006 pred G G UBE2NL UBE2E2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM75P UBE2NL 23023127 pred UBE2V1 UBE2NL 25402006, 23023127 pred RNF4 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2L3 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM56 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF165 23023127 pred G G G G G G G G G TNFAIP3 UBE2NL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2Q1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF125 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PARK2 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G UBE2NL DTX3L 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GOT1 UBE2NL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBQLN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TAX1BP1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF167 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF148 23023127 pred G UBXN2B UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF213 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL RNF181 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2F 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBE2Q2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM40 23023127 pred G UBE2NL UBE2R2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBQLN2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM73 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2I UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BMI1 UBE2NL 23023127 pred BAG6 UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRAF6 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL TRIM59 23023127 pred G G G G G G G G G G G G G G G G G G UBE2NL RNF114 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2NL UBL4B 23023127 pred UBE2M UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBC UBE2NL MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983,21963094,22053931,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_175197|BIOGRID_266688|BIOGRID_178364|BIOGRID_267465|BIOGRID_263809|BIOGRID_266962 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey UBE2NL MEPCE MI:0415(enzymatic study) 17643375 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_121596 prey bait ITGA4 UBE2NL MI:0004(affinity chromatography technology) 22623428 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_261356 bait prey

PPI - HINT Gene A Gene B PMID Method Quality PHGDH UBE2NL 26344197 0401 HT ITGA4 UBE2NL 22623428 0004 HT UBE2NL MEPCE 17643375 0004 HT PHGDH UBE2NL 26344197 0401 HT ITGA4 UBE2NL 22623428 0004 HT UBE2NL MEPCE 17643375 0004 HT PHGDH UBE2NL 26344197 0401 LC VCAM1 UBE2NL 22623428 0030 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5JXB2 O43175 UBE2NL PHGDH 0.081 26344197 Q7L2J0 Q5JXB2 MEPCE UBE2NL 0.126 17643375 Q5JXB2 P13612 UBE2NL ITGA4 0.126 22623428 Q9UBX2 Q5JXB2 DUX4 {ECO:0000312|HGNC:HGNC:50800} UBE2NL 0.126 26816005 Q5JXB2 P19320 UBE2NL VCAM1 0.126 22623428