PTM - CPLM Gene Name UniProt ID Type Position Code Trim25; Efp; Zfp147; Znf147 Q61510 Acetylation 383 K Trim25; Efp; Zfp147; Znf147 Q61510 Acetylation 388 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 200 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 225 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 234 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 282 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 309 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 312 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 319 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 376 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 382 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 407 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 421 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 430 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 442 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 444 K Trim25; Efp; Zfp147; Znf147 Q61510 Ubiquitination 480 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Trim25; Efp; Zfp147; Znf147 Q61510 194 S Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 277 Y Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 381 S Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 401 S Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 404 S Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 410 T Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 424 S Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 84 T Mus musculus(Mouse) Trim25; Efp; Zfp147; Znf147 Q61510 90 T Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q61510 T84-p Phosphorylation LQAEQARtPVDDWtP Q61510 T90-p Phosphorylation RtPVDDWtPPARFSA Q61510 Y270-p Phosphorylation KEEEKRVyGKFDTIy Q61510 Y277-p Phosphorylation yGKFDTIyQVLVkKK Q61510 S381-p Phosphorylation TFkPVQPskKTIQEK Q61510 T393-p Phosphorylation QEKKTKKtPVAPGPP Q61510 S404-p Phosphorylation PGPPSHFsPNkLPTF Q61510 S424-p Phosphorylation SLDSkATsPDAAPkA Q61510 K116-ub Ubiquitination CLTEIAVkTCLVCMA Q61510 K200-ub Ubiquitination ASADLEYkLRNKLTI Q61510 K225-ub Ubiquitination ALEDVRSkQQCVQDS Q61510 K234-ub Ubiquitination QCVQDSMkRKMEQLR Q61510 K282-ub Ubiquitination TIyQVLVkKKSEMQK Q61510 K309-ub Ubiquitination DEFEFLEkAAkLQGE Q61510 K312-ub Ubiquitination EFLEkAAkLQGESTk Q61510 K319-ub Ubiquitination kLQGESTkPVYIPKI Q61510 K344-ub Ubiquitination YQGAADLkSELKHSI Q61510 K376-ub Ubiquitination DQTQSTFkPVQPskK Q61510 K382-ub Ubiquitination FkPVQPskKTIQEKK Q61510 K407-ub Ubiquitination PSHFsPNkLPTFGAP Q61510 K421-ub Ubiquitination PGQSLDSkATsPDAA Q61510 K430-ub Ubiquitination TsPDAAPkASAAQPD Q61510 K442-ub Ubiquitination QPDSVGVkAkVLENF Q61510 K444-ub Ubiquitination DSVGVkAkVLENFLT Q61510 K480-ub Ubiquitination NKVSLSNkYTTASVS

PTM - dbPTM UniProt ID Position Code Type Resources References Q61510 404 S Phosphorylation Phosphositeplus.1010730 19854140 Q61510 424 S Phosphorylation Phosphositeplus.1010730 21183079 Q61510 277 Y Phosphorylation Phosphositeplus.1010730 18563927 Q61510 277 Y Phosphorylation SysPTM 1.1 17242355;18563927

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Trim25 IPI00122289 S 401 VAPGPPpSHFSPNK phosphorylation Trim25 IPI00122289 S 404 GPPSHFpSPNKLPT phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Trim25 Mus musculus (Mouse) 407; 442; 430; 421; 444; 480; 382; 312; 319; 282; 309; 376; 234; 225; 200 "407,SHFSPNKLPTFGA; 442,PDSVGVKAKVLEN; 430,SPDAAPKASAAQP; 421,GQSLDSKATSPDA; 444,SVGVKAKVLENFL; 480,KVSLSNKYTTASV; 382,KPVQPSKKTIQEK; 312,FLEKAAKLQGEST; 319,LQGESTKPVYIPK; 282,IYQVLVKKKSEMQ; 309,EFEFLEKAAKLQG; 376,QTQSTFKPVQPSK; 234,CVQDSMKRKMEQL; 225,LEDVRSKQQCVQD; 200,SADLEYKLRNKLT" 407:22790023; 442:22790023; 430:22790023; 421:22790023; 444:22790023; 480:22790023; 382:22790023; 312:22790023; 319:22790023; 282:22790023; 309:22790023; 376:22790023; 234:22790023; 225:22790023; 200:22790023