PTM - CPLM Gene Name UniProt ID Type Position Code Kmt2a; All1; Hrx; Mll; Mll1 P55200 Acetylation 3781 K Kmt2a; All1; Hrx; Mll; Mll1 P55200 Acetylation 2771 K Kmt2a; All1; Hrx; Mll; Mll1 P55200 Acetylation 2814 K Kmt2a; All1; Hrx; Mll; Mll1 P55200 Acetylation 2954 K Kmt2a; All1; Hrx; Mll; Mll1 P55200 Acetylation 3459 K Kmt2a; All1; Hrx; Mll; Mll1 P55200 Ubiquitination 3693 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Kmt2a; All1; Hrx; Mll; Mll1 P55200 1053 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1056 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1089 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1091 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1103 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1111 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1112 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1116 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1233 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1255 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 134 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 140 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 151 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 159 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 163 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 169 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 179 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 181 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1839 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1841 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1847 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 1860 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 189 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 192 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2100 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2103 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2148 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2152 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2157 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2168 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2173 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2197 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2198 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2199 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2200 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2202 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2240 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2281 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2282 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2538 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2542 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2548 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2560 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2720 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2722 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 277 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2862 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2865 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2867 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 2934 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3022 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3024 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3032 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3034 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3063 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 335 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3508 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3656 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 3949 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 502 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 504 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 509 T Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 514 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 516 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 56 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 692 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 740 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 748 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 750 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 89 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 90 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 93 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 933 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 934 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 935 S Mus musculus(Mouse) Kmt2a; All1; Hrx; Mll; Mll1 P55200 938 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P55200 K214-ac Acetylation KIKKKDSkSIEKKRG P55200 K925-ac Acetylation VGTSSSAkKATGRKK P55200 K1127-ac Acetylation EPLAPPIkPIkPVTR P55200 K1130-ac Acetylation APPIkPIkPVTRNKA P55200 K1342-ac Acetylation EPGPEQSkQKKVAPR P55200 K1369-ac Acetylation EKPPPVSkQENAGTL P55200 K1389-ac Acetylation LSNGISSkQKIPADG P55200 K2436-ac Acetylation KSSKETCkEKHSSKS P55200 S56-p Phosphorylation GGPGAPPsPPAVAAA P55200 S89-p Phosphorylation ASSSSASssSSsSSS P55200 S90-p Phosphorylation SSSSASssSSsSSSA P55200 S93-p Phosphorylation SASssSSsSSSASSG P55200 S159-p Phosphorylation DEEVRVRsPTRsPSV P55200 S163-p Phosphorylation RVRsPTRsPSVKAsP P55200 S169-p Phosphorylation RsPSVKAsPRKPRGR P55200 S181-p Phosphorylation RGRPRSGsDRNPAIL P55200 S189-p Phosphorylation DRNPAILsDPsVFSP P55200 S192-p Phosphorylation PAILsDPsVFSPLNK P55200 S277-p Phosphorylation KLRAGKLsPLKSKFK P55200 T335-p Phosphorylation VRKDKEGtPPLTKED P55200 T422-p Phosphorylation ISSRIIKtPRRFIED P55200 S502-p Phosphorylation QALPEERsNtPEVHT P55200 T504-p Phosphorylation LPEERsNtPEVHTPL P55200 S516-p Phosphorylation TPLPISQsPENESND P55200 S692-p Phosphorylation RFDIHKRsPILRAPR P55200 S740-p Phosphorylation KRKRKVFsPIRSEPR P55200 S748-p Phosphorylation PIRSEPRsPsHSMRT P55200 S750-p Phosphorylation RSEPRsPsHSMRTRS P55200 S933-p Phosphorylation KATGRKKsssLDsGA P55200 S934-p Phosphorylation ATGRKKsssLDsGAD P55200 S935-p Phosphorylation TGRKKsssLDsGADV P55200 S938-p Phosphorylation KKsssLDsGADVAPV P55200 S1111-p Phosphorylation SMGNDDKssVAGsED P55200 S1112-p Phosphorylation MGNDDKssVAGsEDA P55200 S1116-p Phosphorylation DKssVAGsEDAEPLA P55200 S1839-p Phosphorylation KGPGEPDsPtPLHPP P55200 T1841-p Phosphorylation PGEPDsPtPLHPPtP P55200 T1847-p Phosphorylation PtPLHPPtPPILSTD P55200 S1860-p Phosphorylation TDRSREDsPELNPPP P55200 S2100-p Phosphorylation DNRTIAHsPSsFIDA P55200 S2103-p Phosphorylation TIAHsPSsFIDASCK P55200 S2157-p Phosphorylation SYSPTQRsPGCRPLP P55200 S2165-p Phosphorylation PGCRPLPsAGsPTPT P55200 S2168-p Phosphorylation RPLPsAGsPTPTtHE P55200 T2173-p Phosphorylation AGsPTPTtHEIVTVG P55200 S2193-p Phosphorylation SGLRSIGsRRHsTSs P55200 S2197-p Phosphorylation SIGsRRHsTSsLsPL P55200 S2200-p Phosphorylation sRRHsTSsLsPLRSK P55200 S2202-p Phosphorylation RHsTSsLsPLRSKLR P55200 S2410-p Phosphorylation PGMGHRPsILHEHIG P55200 S2538-p Phosphorylation SKNTQKEsGPGsPAH P55200 S2542-p Phosphorylation QKEsGPGsPAHIEsV P55200 S2548-p Phosphorylation GsPAHIEsVCPAEPV P55200 S2862-p Phosphorylation SMQALGEsPESSSSE P55200 S3032-p Phosphorylation PGLQVPVsPtVPVQN P55200 T3034-p Phosphorylation LQVPVsPtVPVQNQK P55200 T3063-p Phosphorylation SNAAVQTtPPHLKPA P55200 S3656-p Phosphorylation QEQKRKEsITERKPK

PTM - dbPTM UniProt ID Position Code Type Resources References P55200 1053 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 1056 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 1091 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 1103 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 1111 S Phosphorylation Phosphositeplus.1010730 21659605 P55200 1112 S Phosphorylation Phosphositeplus.1010730 21183079;21659605 P55200 1116 S Phosphorylation Phosphositeplus.1010730 21183079;21659605 P55200 140 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 151 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 1839 S Phosphorylation Phosphositeplus.1010730 21183079;21659605 P55200 2100 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 2197 S Phosphorylation Phosphositeplus.1010730 18846507;21183079 P55200 2200 S Phosphorylation Phosphositeplus.1010730 19854140 P55200 2202 S Phosphorylation Phosphositeplus.1010730 18846507;21183079 P55200 2542 S Phosphorylation Phosphositeplus.1010730 21183079;21659605 P55200 2560 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 277 S Phosphorylation Phosphositeplus.1010730 19854140;21183079 P55200 2862 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 2865 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 2934 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 3022 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 3032 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 502 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 516 S Phosphorylation Phosphositeplus.1010730 21183079;21659604;21659605 P55200 692 S Phosphorylation Phosphositeplus.1010730 19854140 P55200 740 S Phosphorylation Phosphositeplus.1010730 21183079 P55200 1089 T Phosphorylation Phosphositeplus.1010730 21183079 P55200 1841 T Phosphorylation Phosphositeplus.1010730 19854140;21659605 P55200 1847 T Phosphorylation Phosphositeplus.1010730 21183079;21659605 P55200 3024 T Phosphorylation Phosphositeplus.1010730 21183079 P55200 3034 T Phosphorylation Phosphositeplus.1010730 19854140;21183079 P55200 504 T Phosphorylation Phosphositeplus.1010730 19854140;21659604 P55200 509 T Phosphorylation Phosphositeplus.1010730 21183079

PTM - UniProt UniProt ID Position Type PMIDs P55200 151 Phosphoserine 21183079 P55200 237 N6-acetyllysine 23806337 P55200 371 N6-acetyllysine 23806337 P55200 1053 Phosphoserine 21183079 P55200 1839 Phosphoserine 21183079 P55200 1847 Phosphothreonine 21183079 P55200 2100 Phosphoserine 21183079 P55200 2560 Phosphoserine 21183079 P55200 2954 N6-acetyllysine 23806337 P55200 3459 N6-acetyllysine 23806337