PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Bcr Ubqln1 22451666 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aldoa Ubqln1 15627969 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Hsd3b7 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G Spem1 Ubqln1 20558241 biogrid exp Ywhae Ubqln1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tff1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Dnajb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hk2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Zfand2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Itpripl1 Ubqln1 ortho Hsd17b12 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Col1a2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psma1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stmn3 Ubqln1 ortho P G G G G G G G G G G G G G Clns1a Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmb4 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccne1 Ubqln1 ortho G G G G G G G G G Ntrk1 Ubqln1 ortho Ubqln1 Psmd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Nde1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Tlr4 ortho G G G G G G G G G G G G G G G G G Psmd11 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf1b Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G Atp6v1b2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Smad9 ortho Psen2 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Ube2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Txndc12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kif4 Ubqln1 ortho G G G G G G G G G G Fkbp2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G App Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rad23a Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ticam1 Ubqln1 ortho Nppa Ubqln1 ortho G G G G Ubqln1 Pla2g16 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Tardbp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snrnp70 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabra2 Ubqln1 ortho G G G G G G Hspa1l Ubqln1 ortho P G G G Ahcyl1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pbxip1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd7 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Calu Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3a Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fgf7 Ubqln1 ortho G G G G G G G G Ubqln1 Nupl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Insig2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Uchl3 ortho P Eps15 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psmd13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fcgr3 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Mtor ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Carkd ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Cxx1c protein, Protein Cxx1c ortho G G G G G G G G G G G G G G G G G G G G Bpifa1 Ubqln1 ortho G G G Hspa13 Ubqln1 ortho P Serpine1 Ubqln1 ortho G G G G G G G Ubqln1 Mfi2 ortho G G G Shfm1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Colgalt2 Ubqln1 ortho Ubqln1 Ube2v1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nbl1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G Ubqln1 Agpat5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptn Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G Rad23b Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sssca1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Scg2 Ubqln1 ortho P G G G G G G G G G G G G G Gabra3 Ubqln1 ortho G G G G Wdfy1 Ubqln1 ortho P G G G G G G G G G G G G G G G G G G Cd99l2 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Gpx3 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Ubqln4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mief1 Ubqln1 ortho Atp6v1h Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Efemp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Myg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnpda1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Adrm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Dctpp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sparc Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C1qa Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tmco6 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wibg Ubqln1 ortho P Ubqln1 Sfxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Il6st Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Xpo4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psma6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Chrna3 ortho G G Ubqln1 Ube2c ortho G G G G G G G G G G G G G G G G G G Ubqln1 Bcl2l10 ortho G Gabra6 Ubqln1 ortho G G Ubqln1 Herpud1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Fgfr1op2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Zmym3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Chrnb4 ortho Ubqln1 Trex1 ortho P Ubqln1 Serpini2 ortho P G Ubqln1 Tecr ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim32 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Mief2 Ubqln1 ortho Ubqln1 Erp27 ortho P Ubqln1 Ubl7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp34 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Hgs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd47 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Etnk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rap1gds1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Srebf2 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hes1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Asns Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hbp1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Orai1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stam2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Abcc2 ortho G G G G G Ubqln1 Atxn3 ortho P Psmd14 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Mthfd1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabrb1 Ubqln1 ortho G G G G G G G Grm2 Ubqln1 ortho Chrna4 Ubqln1 ortho G G G G G G G G G Ubqln1 Psmd6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 C1qtnf2 ortho Zg16 Ubqln1 ortho GP G G G G G G G G Uncharacterized protein KIAA1143 homolog Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Nubp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Comtd1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Scg5 Ubqln1 ortho P G G G G G G G G G G G G Vps26a Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc3 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cstf2t Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mcm7 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ep300 Ubqln1 ortho P Rara Ubqln1 ortho G G Gabrd Ubqln1 ortho G G G Ubqln1 Agr3 ortho G G Ubqln1 Sil1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps27a Ubqln1 ortho P Ubqln1 Psma5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd3d Ubqln1 ortho G G G G G G G G G Ubqln1 Ubxn4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Ghrl ortho G G G G Ric8a Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd3 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Mllt6 Ubqln1 ortho G G G G G G G Unk Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G F8 Ubqln1 ortho G G G Fas Ubqln1 ortho G G G G G G G G G G G G G G G G G Eps15l1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Pnma1 Ubqln1 ortho Ubqln1 Ubxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Klhl42 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf1a Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf208 Ubqln1 ortho G G G G G G G G G G G Ubqln1 Ube4b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd4 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppib Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Nme3 ortho P Rassf5 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Fzd7 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vcp Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Agr2 Ubqln1 ortho GP G G G G G G G G Ubqln1 Litaf ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc5 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tlk2 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabra1 Ubqln1 ortho G G G G G G G G Vps4b Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Scmh1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Npy Ubqln1 ortho G G G G G G G G G G G G G G G G G Ube2d1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tpi1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nfyc Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Git2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp9x Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Gkap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Chgb Ubqln1 ortho P G G G G G G G G G G G G G G G G Pdcd6 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psma7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Rnf185 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pik3ip1 Ubqln1 ortho Ubqln1 Ubqln2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppic Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Gnb1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpusd2 Ubqln1 ortho Ubqln1 Triap1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psen1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prap1 Ubqln1 ortho G G G G G G G Cstf2 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Col10a1 Ubqln1 ortho Slc29a2 Ubqln1 ortho G Zmym4 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Ngly1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Ist1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fn1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabrb3 Ubqln1 ortho G G G G G G G Psmc4 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Prpf40a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Map1lc3a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Acot7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Rpn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Manbal ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psmb3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Puf60 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G P4hb Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Parva ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Tmub2 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Rbms1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psmd12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stmn1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Psmd8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fam189a2 Ubqln1 ortho Psmc6 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Efemp1 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Htt Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubqln1 Hypk ortho P G G G G G G G G Ubqln1 Fbxo25 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psma3 Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabrb2 Ubqln1 ortho G G G G G G G G Ubqln1 Tmem37 ortho G G G G G G G G G G G G G G G G G G G Ubqln1 Cyb5r1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ascl1 Ubqln1 ortho G Map3k1 Ubqln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Herc3 Ubqln1 ortho

PPI - HINT Gene A Gene B PMID Method Quality YWHAE UBQLN1 16615898 0027 LC SPEM1 UBQLN1 20558241,20558241 0004,0018 LC UBQLN1 PGLS 16615898 0027 LC UBQLN1 HSD3B7 16615898 0027 LC ALDOA UBQLN1 15627969 0004 LC SPEM1 UBQLN1 20558241,20558241 0004,0018 LC BCR UBQLN1 22451666 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8R317 P62259 UBQLN1 YWHAE 0.081 16615898 Q8R317 Q6PAJ1 UBQLN1 BCR 0.21 22451666 Q8R317 P05064 UBQLN1 ALDOA 0.21 15627969 Q8R317 Q5F289 UBQLN1 SPEM1 0.454 20558241 Q8R317 P32297 UBQLN1 CHRNA3 0.454 16091357 Q8R317 P30926 UBQLN1 CHRNB4 0.21 16091357 Q9CQ60 Q8R317 PGLS UBQLN1 0.081 16615898 Q9EQC1 Q8R317 HSD3B7 UBQLN1 0.081 16615898 Q8R317 P43681 UBQLN1 CHRNA4 0.21 16091357