PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Med8 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tfcp2l1 Med8 20362541 intact exp G G G G G G G G G G G G G G Esrrb Med8 20362541 biogrid exp G G G Med8 Kat2a 20508642 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med30 Med8 24882805 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med19 Med8 24882805 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Med20 24882805 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Med11 24882805 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tada2a Med8 20508642 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med28 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Thra Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Hspb3 ortho G G G G G G Med14 Med8 ortho G G G G G Dvl3 Med8 ortho Krt40 Med8 ortho Med8 Tbl1x ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Trmt112 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pnma1 Med8 ortho Med8 Med29 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ubald1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med10 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Obfc1 Med8 ortho Med31 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Med27 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arrb2 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Med17 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tom1l2 Med8 ortho G G G G G G G G G Ccnc Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med23 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snta1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G Med8 Riok3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Thoc7 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Epas1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G Gtpbp2 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptbp3 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med16 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dmd Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Med9 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbxw7 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smarcc2 Med8 ortho Med18 Med8 ortho Med12 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med21 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arpc2 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med13 Med8 ortho Med26 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Fubp3 Med8 ortho Cops3 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Pex14 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tceb1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med4 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med24 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Trip4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp49 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk8 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nxf1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med6 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Med7 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med22 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul2 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctdp1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpe Med8 ortho Mov10 Med8 ortho G G G G G G G G G G G G G G G G G G G G Med25 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk19 Med8 ortho Smarca2 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smarcd1 Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G Med8 Smarcb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med8 Cpsf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G App Med8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Phyhip Med8 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9D7W5 coimmunoprecipitation 12149480 association C 5 Q9D7W5 Q8C1S0 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 Q9CQI9 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 O75586 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 O75586 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 Q9CQI9 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9R0X0 Q9D7W5 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9R0X0 Q9D7W5 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D8C6 Q9D7W5 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 anti bait coimmunoprecipitation 20508642 association C 47 Q9D7W5 anti bait coimmunoprecipitation 20508642 association C 32 Q9D7W5 A0A024R8C5 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 Q9NVC6 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 Q9NX70 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 A0A024R8B7 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 Q9NVC6 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 A0A024R8C5 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 A0A024R8B7 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9D7W5 Q9NX70 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9H204 Q9D7W5 anti tag coimmunoprecipitation 24882805 physical association X 2 Q9H204 Q9D7W5 anti tag coimmunoprecipitation 24882805 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality YWHAE MED8 16615898 0027 LC TFCP2L1 MED8 20362541 0007 LC ESRRB MED8 20362541 0004 LC MED19 MED8 24882805 0007 LC TADA2A MED8 20508642 0006 LC MED30 MED8 24882805 0007 LC MED8 MED11 24882805 0007 LC MED8 KAT2A 20508642 0006 LC MED8 MED20 24882805 0007 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9D7W5 Q61539 MED8 ESRRB 0.126 20362541 Q9D7W5 Q8CHV6 MED8 TADA2A 0.126 20508642 Q9D7W5 P62259 MED8 YWHAE 0.081 16615898 Q9JHD2 Q9D7W5 KAT2A MED8 0.126 20508642 Q9D7W5 O75586 MED8 MED6 0.126 24882805 Q9D7W5 Q15528 MED8 MED22 0.126 24882805 Q9D7W5 Q6P2C8 MED8 MED27 0.126 24882805 Q9D7W5 Q8C1S0 MED8 MED19 0.126 24882805 Q9D7W5 Q9CQI9 MED8 MED30 0.126 24882805 Q9D8C6 Q9D7W5 MED11 MED8 0.126 24882805 Q9H204 Q9D7W5 MED28 MED8 0.126 24882805 Q9NVC6 Q9D7W5 MED17 MED8 0.126 24882805 Q9NX70 Q9D7W5 MED29 MED8 0.126 24882805 Q9R0X0 Q9D7W5 MED20 MED8 0.126 24882805