PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Rps27a Ahi1 21565611 biogrid exp Rps27a Egln3 i2d exp Rps27a Iqcb1 21565611 biogrid exp Rps27a Nphp1 21565611 biogrid,intact exp Nphp4 Rps27a 21565611 biogrid exp Rps27a Uncharacterized protein C17orf96 homolog 23180766 biogrid exp Rps27a Mks1 21565611 biogrid exp Rps27a Trim21 23222971 intact exp Invs Rps27a 21565611 biogrid exp Hmga2 Rps27a 26045162 intact exp Rps27a Eed 24457600 biogrid exp, ortho Rps7 Rps27a ortho P Rps3 Rps27a ortho P Rps27a Usp14 ortho P Rps27a Tuba4a ortho P Exoc6b Rps27a ortho Rps27a Isg15 ortho P Rps27a Sptlc2 ortho P Rps27a Acaca ortho P Atp5b Rps27a ortho P Rps27a Uchl3 ortho P Rps27a Egfr ortho P Psmc5 Rps27a ortho P Rps27a Polr3h ortho Rps27a Ankrd13d ortho P Rps27a Osgep ortho Rad23b Rps27a ortho P Rps27a Rps10 ortho P Rps27a Ywhaz ortho P Ube2k Rps27a ortho P Rps27a Usp7 ortho P Rplp0 Rps27a ortho P Rps27a Cct6a ortho Rps13 Rps27a ortho P Rps8 Rps27a ortho P Rps27a Flot2 ortho P Rpl18a Rps27a ortho P Rps27a Cdk2 ortho P Rps27a Atp1a3 ortho P Rps27a Cnot6l ortho Rps11 Rps27a ortho P Rps27a Nle1 ortho P Rps27a Mef2d ortho Daxx Rps27a ortho Usp5 Rps27a ortho P Rps26 Rps27a ortho P Rps27a Fat4 ortho Rps27a Grb2 ortho P Ntn1 Rps27a ortho Rps27a Rpl15 ortho P Rps27a Gsk3b ortho P Rps27a Vcp ortho P Rpl10a Rps27a ortho P Rps27a Ubxn1 ortho P Rps27a Phgdh ortho P Ube2e3 Rps27a ortho P Rps27a Pfkp ortho P Rps27a Rpl11 ortho P Rps27a Nat10 ortho P Rps27a Gpn1 ortho P Rps27a Prodh ortho P Rpl18 Rps27a ortho P Rps27a Gga1 ortho P Rps27a Plk4 ortho Rps27a Tars ortho P Msn Rps27a ortho P Cdk14 Rps27a ortho Rps27a Ube2r2 ortho P Rps27a Rac1 ortho P Tnfrsf1a Rps27a ortho Dvl1 Rps27a ortho Rps27a Pacsin1 ortho P Protein Dhx35 Rps27a ortho Rps27a Yod1 ortho Vcam1 Rps27a ortho P Rps27a Gnl2 ortho Rps27a Ipo5 ortho P Rps27a Rnf11 ortho Rps15a Rps27a ortho P Rps27a Tlr2 ortho Dusp1 Rps27a ortho Rps27a Polh ortho Tom1 Rps27a ortho P Rps27a Ahsa1 ortho P Rps27a Tsg101 ortho P Rps27a Taf5 ortho Rps27a Usp1 ortho Rps27a Smad4 ortho P Rps27a Nkd1 ortho Rps27a Orc1 ortho Rps27a Mecr ortho P Rps27a Acox1 ortho P Rps27a Atp6v1c1 ortho P Scd2 Rps27a ortho P Rps2 Rps27a ortho P Shmt1 Rps27a ortho P Rps27a Rpl4 ortho P Rps27a Ddx19a ortho P Fshr Rps27a ortho Rps6 Rps27a ortho P Rps27a Strap ortho P Rps27a Dnajb2 ortho P Rps27a Map3k3 ortho P Hsp90ab1 Rps27a ortho P Ubc Rps27a ortho P Rps27a Polyadenylate-binding protein, PABP ortho P Rps27a Vcl ortho P Rps27a Taf9 ortho Rps27a Dph1 ortho Brca1 Rps27a ortho Rps16 Rps27a ortho P Pten Rps27a ortho P Rps27a Cct2 ortho P Rps27a Thap7 ortho Rps27a Mark3 ortho Rps27a Tada2a ortho Mdm2 Rps27a ortho Rps27a Malt1 ortho Rps27a Sqstm1 ortho P Rps27a Rps19 ortho P Rpl21 Rps27a ortho P Rps27a Gabarap ortho P Fyn Rps27a ortho Rps27a Add1 ortho P Bmpr1b Rps27a ortho Acvr1 Rps27a ortho Psmd4 Rps27a ortho P Rps27a Syap1 ortho P Rps27a Uba1 ortho P Rps27a Nsun2 ortho P Rps27a Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 ortho P Rps27a Rpl19 ortho P Rps27a Frk ortho P Rpl7a Rps27a ortho P Cdkn1b Rps27a ortho Rps27a Bap1 ortho Rps27a Ddx4 ortho P Fn1 Rps27a ortho P Rps27a Kpnb1 ortho P Rps27a Nkd2 ortho Rps27a Trim25 ortho P Pola1 Rps27a ortho P Rps27a Zranb1 ortho Rps27a Prkacb ortho P Rps27a Mast2 ortho Rps27a Fbxo25 ortho Rps27a Sncaip ortho Rps27a Ino80 ortho Rps27a Ctnnb1 ortho P Rps27a Denr ortho P Lyn Rps27a ortho P Rps27a Gfpt2 ortho P Rps27a Pan2 ortho Gabarapl2 Rps27a ortho P Rps27a Rpl14 ortho P Rps27a Csnk1e ortho Rps27a Dvl3 ortho Kansl3 Rps27a ortho Rpl5 Rps27a ortho P Rps27a Kat2b ortho Ddi2 Rps27a ortho P Axin2 Rps27a ortho Atp6v1e1 Rps27a ortho P Smo Rps27a ortho Rps27a Smad1 ortho P Plaa Rps27a ortho P Rps27a Ubqln1 ortho P Rps27a Taf6 ortho Rps27a Taf10 ortho P Rps27a Dutp ortho Rps27a Rps5 ortho P Rps27a Arrb2 ortho P Rps27a Dazap2 ortho Rps27a Park2 ortho Rpl31 Rps27a ortho P Rps27a Ddx54 ortho Rpl23 Rps27a ortho P Rps24 Rps27a ortho P Rps27a Rpf2 ortho Rps27a Dvl2 ortho Rps27a Usp22 ortho Rps27a Rad21 ortho P Rps27a Gga3 ortho Rps27a Polr2b ortho P Rps27a Gtpbp4 ortho P Gpi Rps27a ortho P Ncam1 Rps27a ortho Rps27a D6Wsu163e ortho Rps27a Arrb1 ortho P Ube2g2 Rps27a ortho P Sar1a Rps27a ortho P Rpl9 Rps27a ortho P Rps27a Apc ortho P Rps27a Rpl24 ortho Polr2g Rps27a ortho P Syk Rps27a ortho P Rps27a Camk1d ortho P App Rps27a ortho P Rps27a Bin3 ortho Rps27a Smad2 ortho P Rps23 Rps27a ortho P Rps27a Smurf1 ortho Rps27a Ftsj3 ortho P Rps27a Tgfbr1 ortho Rpl37a Rps27a ortho P Rps27a Rabgef1 ortho P Esr2 Rps27a ortho Cdk5 Rps27a ortho P Cd247 Rps27a ortho Rps27a Tubb4b ortho P Cdc6 Rps27a ortho Sstr2 Rps27a ortho Rps27a Dkc1 ortho P Jun Rps27a ortho Rps27a Cyb5b ortho P Rps27a Rpl10l ortho P Rps27a Pole ortho P Rps27a Map1lc3b ortho P Ikbkg Rps27a ortho P Rps27a Smyd5 ortho P Rps27a Puf60 ortho P Ctsg Rps27a ortho Rps27a Ppp2r2b ortho P Rps27a Laptm5 ortho Rps27a Rpl10 ortho P Rps27a Rhoa ortho P Ifrd1 Rps27a ortho P Hnrnpa2b1 Rps27a ortho P Rpsa Rps27a ortho P Rps27a Nedd4l ortho P Rps27a Rps27a ortho P Rps27a Polr2c ortho P Ywhae Rps27a ortho P Psmc3 Rps27a ortho P Rps27a Rpl22 ortho P Rps27a Stambp ortho P Cnbp Rps27a ortho P Rps27a Nsfl1c ortho P Tp53 Rps27a ortho Hsd17b12 Rps27a ortho P Rps27a Gnb2l1 ortho P Braf Rps27a ortho P Eif4a2 Rps27a ortho P Rps27a Rps12 ortho P Rps27a Traf6 ortho Rps27a Znf512b ortho Ddx6 Rps27a ortho P Rps27a Eps15l1 ortho P Rps27a Dcun1d2 ortho Rps27a Csnk1a1 ortho P Rps27a Map1lc3a ortho P Rps27a Trnau1ap ortho Rps27a Itga4 ortho Rps27a Ttc25 ortho P Rps27a Gabarapl1 ortho P Fau Rps27a ortho P Rps27a Bicd2 ortho P Rps27a Notch1 ortho Smurf2 Rps27a ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P62983 Q8BP00 affinity chromatography technology 21565611 physical association X 2 P62983 Q15796-2 affinity chromatography technology 15761153 physical association X 2 P62983 D3DPA4 affinity chromatography technology 15761153 physical association X 2 O00238 P62983 affinity chromatography technology 15761153 physical association X 2 P62983 affinity chromatography technology 21565611 physical association X 2 P62983 A2APS1 affinity chromatography technology 21565611 physical association X 2 P62983 P59240 affinity chromatography technology 21565611 physical association X 2 P62983 O89019 affinity chromatography technology 21565611 physical association X 2 P62983 Q7TNS8 affinity chromatography technology 23180766 physical association X 2 P62983 Q921E6 affinity chromatography technology 24457600 physical association X 2 P62983 A0A024R274 affinity chromatography technology 15761153 physical association X 2 P62983 P36897 affinity chromatography technology 15761153 physical association X 2 P62983 affinity chromatography technology 15761153 physical association X 2 Q284W0 P62983 affinity chromatography technology 21565611 physical association X 2 P62983 anti bait coimmunoprecipitation 23222971 association C 21 P62983 anti tag coimmunoprecipitation 21565611 association C 13

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Rps27a uniprotkb:(gene name) MI:0004(affinity chromatography technology) 23180766 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_328802 prey bait Rps27a Mks1 MI:0004(affinity chromatography technology) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326577 prey bait Invs Rps27a MI:0004(affinity chromatography technology) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326864 bait prey Nphp4 Rps27a MI:0004(affinity chromatography technology) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326709 bait prey Rps27a Ahi1 MI:0004(affinity chromatography technology) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326537 prey bait Rps27a Nphp1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_113731|UniProt_172311|BIOGRID_326617 prey|prey|prey bait|bait|bait Rps27a Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332904 prey bait Rps27a Iqcb1 MI:0004(affinity chromatography technology) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326742 prey bait

PPI - HINT Gene A Gene B PMID Method Quality INVS RPS27A 21565611 0004 HT HMGA2 RPS27A 26045162 0096 LC RAB4A RPS27A 26885862 0676 LC NPHP4 RPS27A 21565611 0004 HT RPS27A MKS1 21565611 0004 HT RPS27A TRIM21 23222971 0006 LC RPS27A Q7TNS8 23180766 0004 LC RPS27A IQCB1 21565611 0004 HT RPS27A AHI1 21565611 0004 HT RPS27A EED 24457600 0004 LC RPS27A NPHP1 21565611,21565611 0004,0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P62983 P59240 RPS27A NPHP4 0.126 21565611 Q5SW45 P62983 MKS1 RPS27A 0.126 21565611 Q04771 P62983 ACVR1 RPS27A 0.126 15761153 Q9HCE7 P62983 SMURF1 RPS27A 0.126 15761153 Q7TNS8 P62983 Q7TNS8 RPS27A 0.21 23180766 Q8BP00 P62983 IQCB1 RPS27A 0.126 21565611 Q9QY53 P62983 NPHP1 RPS27A 0.236 21565611 P62983 P36897 RPS27A TGFBR1 0.126 15761153 Q921E6 P62983 EED RPS27A 0.126 24457600 Q13485 P62983 SMAD4 RPS27A 0.126 15761153 Q15796 P62983 SMAD2 RPS27A 0.126 15761153 P62983 O00238 RPS27A BMPR1B 0.126 15761153 P62983 P52927 RPS27A HMGA2 0.126 26045162 P62983 P56371 RPS27A RAB4A 0.126 26885862