PTM - CPLM Gene Name UniProt ID Type Position Code Atxn3; Mjd Q9CVD2 Ubiquitination 291 K Atxn3; Mjd Q9CVD2 Ubiquitination 346 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Atxn3; Mjd Q9CVD2 203 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 219 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 263 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 268 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 271 T Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 272 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 273 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 277 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 29 S Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 313 T Mus musculus(Mouse) Atxn3; Mjd Q9CVD2 321 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9CVD2 S29-p Phosphorylation LLQGEYFsPVELSSI Q9CVD2 S219-p Phosphorylation VLEAADGsGIFDEDE Q9CVD2 S263-p Phosphorylation SMQGSSRsMCENsPQ Q9CVD2 S268-p Phosphorylation SRsMCENsPQtssPD Q9CVD2 T271-p Phosphorylation MCENsPQtssPDLSS Q9CVD2 S272-p Phosphorylation CENsPQtssPDLSSE Q9CVD2 S273-p Phosphorylation ENsPQtssPDLSSEE Q9CVD2 S321-p Phosphorylation TSSGGRRsDQGGDAV Q9CVD2 K117-ub Ubiquitination RSFICNYkEHWFTVR Q9CVD2 K200-ub Ubiquitination GEELAHLkEQSALkA Q9CVD2 K206-ub Ubiquitination LkEQSALkADLERVL Q9CVD2 K291-ub Ubiquitination RREAYFEkQQQQQQE Q9CVD2 K346-ub Ubiquitination TMSLETAkDNLKAER

PTM - dbPTM UniProt ID Position Code Type Resources References Q9CVD2 219 S Phosphorylation Swiss-Prot 1010711 15345747 Q9CVD2 268 S Phosphorylation Swiss-Prot 1010711 17242355 Q9CVD2 273 S Phosphorylation Swiss-Prot 1010711 17242355 Q9CVD2 219 S Phosphorylation PhosphoELM.10011 15345747 Q9CVD2 268 S Phosphorylation PhosphoELM.10011 17242355 Q9CVD2 273 S Phosphorylation PhosphoELM.10011 17242355 Q9CVD2 219 S Phosphorylation Phosphositeplus.1010730 15345747;19854140;21183079 Q9CVD2 263 S Phosphorylation Phosphositeplus.1010730 17242355;21183079 Q9CVD2 268 S Phosphorylation Phosphositeplus.1010730 17242355;20531401;21183079;21659605 Q9CVD2 272 S Phosphorylation Phosphositeplus.1010730 21183079 Q9CVD2 273 S Phosphorylation Phosphositeplus.1010730 17242355;20531401;21183079 Q9CVD2 29 S Phosphorylation Phosphositeplus.1010730 20347968 Q9CVD2 321 S Phosphorylation Phosphositeplus.1010730 17242355;19854140;21183079 Q9CVD2 271 T Phosphorylation Phosphositeplus.1010730 21183079 Q9CVD2 264 M Oxidation SysPTM 1.1 17242355 Q9CVD2 333 M Oxidation SysPTM 1.1 17242355 Q9CVD2 219 S Phosphorylation SysPTM 1.1 15345747 Q9CVD2 263 S Phosphorylation SysPTM 1.1 17242355 Q9CVD2 268 S Phosphorylation SysPTM 1.1 17242355 Q9CVD2 273 S Phosphorylation SysPTM 1.1 17242355 Q9CVD2 321 S Phosphorylation SysPTM 1.1 17242355

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9CVD2 219 S 15345747 HTP Phosphorylation Q9CVD2 273 S 17242355 HTP Phosphorylation Q9CVD2 268 S 17242355 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9CVD2 219 Phosphoserine 15345747;21183079 Q9CVD2 268 Phosphoserine 17242355;21183079 Q9CVD2 272 Phosphoserine 21183079 Q9CVD2 273 Phosphoserine 17242355;21183079 Q9CVD2 321 Phosphoserine 21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Atxn3 IPI00138394 S 268 RSMCENpSPQTSSP phosphorylation Atxn3 IPI00138394 S 273 NSPQTSpSPDLSSE phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Atxn3 Mus musculus (Mouse) 346; 291; 206; 200 "346,MSLETAKDNLKAE; 291,REAYFEKQQQQQQ; 206,KEQSALKADLERV; 200,EELAHLKEQSALK" 346:22790023; 291:22790023; 206:22790023; 200:22790023