PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Raf1 Sorbs3 15836771 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Sorbs3 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rarg Sorbs3 15734736 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Socs7 Sorbs3 15242778 biogrid exp, ortho G G G G G G G Inppl1 Sorbs3 16302969 mint,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wasf2 Sorbs3 16483316 mint,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dvl2 Sorbs3 ortho G G G G G G G G G G G G Pak7 Sorbs3 ortho Prkaca Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Efs Sorbs3 ortho G G G G G G G G G G G G G G G G G G G Mapk3 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pak2 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dmrtb1 Sorbs3 ortho G Ccdc22 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Abl1 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cbl Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Zc4h2 Sorbs3 ortho MCG10049, Protein Zbtb25 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G Ube2t Sorbs3 ortho P G G G G G G G G G G G G Zbtb7b Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G Rapgef2 Sorbs3 ortho Nckipsd Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Alb Sorbs3 ortho GP G G G G G G G G G G G G G G G G G Bag3 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bcam Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G Atp6v1h Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Safb2 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Txndc17 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dlg5 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G Vars2 Sorbs3 ortho Arnt2 Sorbs3 ortho G G G Sorbs3 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc42bpa Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Sorbs3 Katna1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Syp Sorbs3 ortho G G G G G G G G G G G Mapk1 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps37c Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx17 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sh2d4a Sorbs3 ortho P Srcin1 Sorbs3 ortho P BC045600 Sorbs3 ortho Ptk6 Sorbs3 ortho G G G Saxo1 Sorbs3 ortho Syncrip Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Skt Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Akt1 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sorbs3 Rbmx ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Rtkn Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G Notch3 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Faslg Sorbs3 ortho G Wasf1 Sorbs3 ortho GP G G G G G G G G G G G G G G G Adamtsl4 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G Flot1 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim23 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Adam15 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim27 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dip2a Sorbs3 ortho P Eif3h Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hnrnpk Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G MCG7194, isoform CRA_a, Protein 9330159F19Rik Sorbs3 ortho Kras Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps37b Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Trim41 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cpsf7 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hnrnpul1 Sorbs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cblb Sorbs3 ortho Cpne2 Sorbs3 ortho G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8VHQ2 Q9R1Z8 affinity chromatography technology 15242778 physical association X 2 P18911-2 Q9R1Z8 affinity chromatography technology 15734736 physical association X 2 Q99N57 Q9R1Z8 affinity chromatography technology 15836771 physical association X 2 Q9R1Z8 cosedimentation 16615898 colocalization C 1216 Q6P549 Q9R1Z8 anti bait coimmunoprecipitation 16302969 physical association X 2 Q9R1Z8 Q8BH43 anti bait coimmunoprecipitation 16483316 physical association X 2 P12003-1 Q9R1Z8 pull down 12473693 physical association X 2 A8K3H3 Q9R1Z8 two hybrid 15734736 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9R1Z8 P62259 SORBS3 YWHAE 0.081 16615898 Q9R1Z8 Q6P549 SORBS3 INPPL1 0.21 16302969 Q9R1Z8 P13631 SORBS3 RARG 0.309 15734736 Q9R1Z8 Q8VHQ2 SORBS3 SOCS7 0.21 15242778 Q9R1Z8 Q99N57 SORBS3 RAF1 0.21 15836771 Q9R1Z8 Q8BH43 SORBS3 WASF2 0.21 16483316 Q9R1Z8 P18911 SORBS3 RARG 0.21 15734736