PTM - CPLM Gene Name UniProt ID Type Position Code Usp25 P57080 Acetylation 722 K Usp25 P57080 Ubiquitination 57 K Usp25 P57080 Ubiquitination 201 K Usp25 P57080 Ubiquitination 250 K Usp25 P57080 Ubiquitination 254 K Usp25 P57080 Ubiquitination 312 K Usp25 P57080 Ubiquitination 313 K Usp25 P57080 Ubiquitination 392 K Usp25 P57080 Ubiquitination 444 K Usp25 P57080 Ubiquitination 521 K Usp25 P57080 Ubiquitination 585 K Usp25 P57080 Ubiquitination 623 K Usp25 P57080 Ubiquitination 631 K Usp25 P57080 Ubiquitination 699 K Usp25 P57080 Ubiquitination 716 K Usp25 P57080 Ubiquitination 722 K Usp25 P57080 Ubiquitination 790 K Usp25 P57080 Ubiquitination 1011 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Usp25 P57080 61 T Mus musculus(Mouse) Usp25 P57080 681 T Mus musculus(Mouse) Usp25 P57080 740 Y Mus musculus(Mouse) Usp25 P57080 82 S Mus musculus(Mouse) Usp25 P57080 85 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P57080 T61-p Phosphorylation LTAkNAKtPPQEETG P57080 Y69-p Phosphorylation PPQEETGyYQTALPG P57080 Y425-p Phosphorylation EIKRLKDyLtVLQQR P57080 T427-p Phosphorylation KRLKDyLtVLQQRLE P57080 T681-p Phosphorylation QALVGMEtLPPDLRD P57080 Y740-p Phosphorylation AQAGGADyLEQPSRS P57080 K41-ub Ubiquitination QILQQALkDSNGNLE P57080 K57-ub Ubiquitination AVAFLTAkNAKtPPQ P57080 K99-ub Ubiquitination IDLTGDDkDDLQRAI P57080 K201-ub Ubiquitination RRLVLNYkPPSNAQD P57080 K250-ub Ubiquitination SRAVEILkDAFkSND P57080 K254-ub Ubiquitination EILkDAFkSNDSQQQ P57080 K312-ub Ubiquitination AMGVLEGkkFENTEM P57080 K313-ub Ubiquitination MGVLEGkkFENTEMF P57080 K392-ub Ubiquitination RPEKIHNkLEFPQVL P57080 K444-ub Ubiquitination LSYGSGPkRFPLVDV P57080 K521-ub Ubiquitination PLRSVIHkPFTQSRI P57080 K585-ub Ubiquitination IELMYSDkSMIQVPY P57080 K623-ub Ubiquitination HRESRWMkYNDIAVT P57080 K631-ub Ubiquitination YNDIAVTkSSWEELV P57080 K699-ub Ubiquitination EDNQRFEkELEEWDT P57080 K716-ub Ubiquitination AQRSLQEkLLAAPkL P57080 K722-ub Ubiquitination EkLLAAPkLREAEAS P57080 K790-ub Ubiquitination LEYSRLVkLAQEDTP P57080 K1011-ub Ubiquitination KLTDFLPkLLDCSTE

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Usp25 IPI00331006 S 82 GNDRYIpSVGSQAD phosphorylation Usp25 IPI00331006 S 85 RYISVGpSQADANV phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Usp25 Mus musculus (Mouse) 699; 312; 313; 392; 722; 790; 716; 521; 585; 623; 631; 444; 250; 254; 201; 57; 1011 "699,DNQRFEKELEEWD; 312,MGVLEGKKFENTE; 313,GVLEGKKFENTEM; 392,PEKIHNKLEFPQV; 722,KLLAAPKLREAEA; 790,EYSRLVKLAQEDT; 716,QRSLQEKLLAAPK; 521,LRSVIHKPFTQSR; 585,ELMYSDKSMIQVP; 623,RESRWMKYNDIAV; 631,NDIAVTKSSWEEL; 444,SYGSGPKRFPLVD; 250,RAVEILKDAFKSN; 254,ILKDAFKSNDSQQ; 201,RLVLNYKPPSNAQ; 57,VAFLTAKNAKTPP; 1011,LTDFLPKLLDCST" 699:22790023; 312:22790023; 313:22790023; 392:22790023; 722:22790023; 790:22790023; 716:22790023; 521:22790023; 585:22790023; 623:22790023; 631:22790023; 444:22790023; 250:22790023; 254:22790023; 201:22790023; 57:22790023; 1011:22790023