PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Plaa Unk 25737280 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Hdac6 11689694 biogrid,i2d,mint,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Aldh4a1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Vcp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Polr1a Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Tubb2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Aspscr1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Twf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Cnbp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Ubxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf169 Plaa ortho Plaa Ppp1cb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Fdps ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Ca14 ortho G G G G G G G G G G G G G G G Plaa Basp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Polr1b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Yod1 ortho Plaa Srprb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Egfr ortho GP G G G G G G G G G G G G G G G G G Plaa Rnf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcna Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Ufd1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Pak2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Cse1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Ntrk1 ortho Psmd14 Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Ubxn6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Lypd3 ortho G G G Prkce Plaa ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Flot2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Xaa-Pro aminopeptidase 1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Parp6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccdc85c Plaa ortho Plaa Faf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Nploc4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Rps27a ortho P Plaa Nt5e ortho G G G G G G G G G G G G Plaa Ubxn7 ortho P Plaa Pdia3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Pla2g1b ortho GP G G G G G G G G Plaa Tufm ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hk1 Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpna4 Plaa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Th Plaa ortho P G G G G G G G Plaa Scn2b ortho Plaa Faf2 ortho P Plaa Nsfl1c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaa Cav1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P27612 Q3UG37 affinity chromatography technology 11689694 physical association X 2 P0CG63 P27612 affinity chromatography technology 21070969 physical association X 2 Q9Z2V5 P27612 anti bait coimmunoprecipitation 11689694 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Plaa Hdac6 MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down) 11689694 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_311506|MINT_58116|UniProt_161789 prey|prey|prey bait|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality PLAA RAB32 26885862 0676 LC PLAA HDAC6 11689694,11689694 0004,0006 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P27612 P0CG63 PLAA UBI4 0.21 21070969 Q8BL48 P27612 UNK PLAA 0.126 25737280 Q9CZE3 P27612 RAB32 PLAA 0.126 26885862 Q9Z2V5 P27612 HDAC6 PLAA 0.376 11689694