PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Vps36 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Vps36 17057714 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Atg7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Vps25 ortho P G G Tnfaip2 Vps36 ortho G G G G G G G G G G G G G G G G G G G G G G G Vps36 Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Slc25a41 Vps36 ortho Ppp3cb Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tsg101 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdlbp Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps26a Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Vps28 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp1 Vps36 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Elavl1 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trmt61a Vps36 ortho P Ttc4 Vps36 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Cul5 ortho P Vps36 Vps35 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map2k1 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Snf8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc5l Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Vps29 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Wdr12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Chmp6 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mov10 Vps36 ortho G G G G G G G G G G G G G G G G G G G G Rbbp5 Vps36 ortho Vps36 Twf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gcnt1 Vps36 ortho G G G G G G G G Vps36 Znhit2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Ube4b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Spry2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ecm29 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Dnajb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Acbd3 Vps36 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snx15 Vps36 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Chmp4b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps36 Chmp2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rilp Vps36 ortho Vps36 Nxt1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q91XD6 P0CG50 x-ray crystallography 17057714 association X 2 Q91XD6 P0CG50 pull down 17057714 direct interaction X 2 Q91XD6 P0CG48 pull down 15755741 direct interaction X 2 Q91XD6 P63048 surface plasmon resonance 17057714 direct interaction X 2 Q91XD6 P63048 x-ray crystallography 17057714 direct interaction X 2 Q91XD6 cosedimentation 16615898 colocalization C 1216

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Vps36 Vps36 MI:0107(surface plasmon resonance) 17057714 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) MI:0465(dip) DIP_345 - - Ubc Vps36 MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography) 17057714 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0914(association) (biogrid)|(biogrid) BIOGRID_320814|BIOGRID_320813 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q91XD6 P62259 VPS36 YWHAE 0.081 16615898 Q91XD6 P0CG48 VPS36 UBC 0.309 15755741 Q91XD6 P0CG50 VPS36 UBC 0.523 17057714 Q91XD6 P62990 VPS36 UBA52 0.523 17057714