PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TNF receptor-associated factor 5 Traip 17544371 innatedb exp Traf6 Traip 17544371 innatedb exp, ortho G G G Traip Tbk1 22945920 biogrid exp, ortho G G G G G G G G Traf2 Traip 17544371 innatedb exp, ortho G G G G Trim41 Traip ortho G G G G G G G G Rad21 Traip ortho G G G G G G G G App Traip ortho G G G G G G G G Plcg1 Traip ortho Traf3 Traip ortho G G G G G G G Tnfrsf1b Traip ortho G G G Traip Flii ortho G G G G G G G G Ube2u Traip ortho Ube2d1 Traip ortho G G G G G G G G Ube2d2 Traip ortho G G G G G G G G Cyld Traip ortho Ube2z Traip ortho G G G G G G G G Traip Nck1 ortho G G G G G G G G Syk Traip ortho G G G Traf1 Traip ortho G Traip Rnf4 ortho G G G G G G G G Ube2d3 Traip ortho G G G G G G G G Fyn Traip ortho G G G G G G G G Traf5 Traip ortho G G G Tsg101 Traip ortho G G G G G G G G Ube2k Traip ortho G G G G G G G G Tnfrsf8 Traip ortho Traip Ubox5 ortho G G G G G G Traip Traip ortho G G G G G G G G Usp2 Traip ortho G G G G G Grb2 Traip ortho G G G G G G G G Traip Rnf114 ortho G G G G G G G G Ube2h Traip ortho G G G G G G G G Trim23 Traip ortho G G G G G G G G Traip Polk ortho G G G G G G G G Traip Polh ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8VIG6 P39428 - 9104814 - X 2 Q8VIG6 Q9WUN2 affinity chromatography technology 22945920 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Traip Tbk1 MI:0004(affinity chromatography technology) 22945920 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322285 prey bait

PPI - HINT Gene A Gene B PMID Method Quality TRAF2 TRAIP 17544371 0096 LC TRAF5 TRAIP 17544371 0096 LC TRAF6 TRAIP 17544371 0096 LC TRAIP TBK1 22945920 0004 LC