PTM - CPLM Gene Name UniProt ID Type Position Code Sec31a; Sec31l1 Q3UPL0 Acetylation 71 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 111 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 206 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 435 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 470 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 487 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 502 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 509 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 646 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 706 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 722 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 728 K Sec31a; Sec31l1 Q3UPL0 Ubiquitination 791 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Sec31a; Sec31l1 Q3UPL0 1171 T Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 1173 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 1175 T Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 1223 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 350 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 433 T Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 520 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 526 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 531 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 620 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 712 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 794 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 798 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 799 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 801 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 803 Y Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 809 S Mus musculus(Mouse) Sec31a; Sec31l1 Q3UPL0 820 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q3UPL0 K118-ac Acetylation kEVVIAQkDKHTGPV Q3UPL0 R423-m2 Methylation QGAEQQRrQPVFISQ Q3UPL0 S397-p Phosphorylation IRRPVGAsFSFGGKL Q3UPL0 T433-p Phosphorylation VFISQVVtEkDFLNR Q3UPL0 S526-p Phosphorylation DSDQVAQsDGEEsPA Q3UPL0 S531-p Phosphorylation AQsDGEEsPAAEEQL Q3UPL0 S794-p Phosphorylation KAQGkPVsGQESsQs Q3UPL0 S799-p Phosphorylation PVsGQESsQsPyERQ Q3UPL0 S801-p Phosphorylation sGQESsQsPyERQPL Q3UPL0 Y803-p Phosphorylation QESsQsPyERQPLSK Q3UPL0 T1171-p Phosphorylation YDKLREQtLsPtIIN Q3UPL0 S1173-p Phosphorylation KLREQtLsPtIINGL Q3UPL0 T1175-p Phosphorylation REQtLsPtIINGLHS Q3UPL0 K111-ub Ubiquitination SKIIAGDkEVVIAQk Q3UPL0 K206-ub Ubiquitination RKNEPIIkVSDHSNR Q3UPL0 K435-ub Ubiquitination ISQVVtEkDFLNRSA Q3UPL0 K470-ub Ubiquitination ASQTEFEkNVWSFLk Q3UPL0 K477-ub Ubiquitination kNVWSFLkVNFEEDS Q3UPL0 K487-ub Ubiquitination FEEDSRGkYLELLGY Q3UPL0 K502-ub Ubiquitination RKEDLGQkIALALNk Q3UPL0 K509-ub Ubiquitination kIALALNkVDGPDVA Q3UPL0 K614-ub Ubiquitination ELLAQTQkKYFAKSQ Q3UPL0 K646-ub Ubiquitination IVESCDLkNWREALA Q3UPL0 K706-ub Ubiquitination RLVACWTkAQDGSSP Q3UPL0 K722-ub Ubiquitination SLQDLIEkVVILRkA Q3UPL0 K728-ub Ubiquitination EkVVILRkAVQLTQA Q3UPL0 K791-ub Ubiquitination RLCKAQGkPVsGQES

PTM - dbPTM UniProt ID Position Code Type Resources References Q3UPL0 526 S Phosphorylation Swiss-Prot 1010711 17203969;18630941;19131326 Q3UPL0 526 S Phosphorylation PhosphoELM.10011 17203969 Q3UPL0 803 Y Phosphorylation PhosphoELM.10011 15592455 Q3UPL0 1173 S Phosphorylation Phosphositeplus.1010730 20415495;21183079 Q3UPL0 520 S Phosphorylation Phosphositeplus.1010730 21183079 Q3UPL0 526 S Phosphorylation Phosphositeplus.1010730 17203969;17242355;18846507;19367708;19854140;20415495;20531401;21183079;21659604;21659605 Q3UPL0 531 S Phosphorylation Phosphositeplus.1010730 17203969;19367708;20415495;20531401;21183079;21659604;21659605 Q3UPL0 801 S Phosphorylation Phosphositeplus.1010730 21659604 Q3UPL0 820 S Phosphorylation Phosphositeplus.1010730 21183079 Q3UPL0 1175 T Phosphorylation Phosphositeplus.1010730 20415495 Q3UPL0 803 Y Phosphorylation Phosphositeplus.1010730 15592455

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q3UPL0 526 S 17203969 HTP Phosphorylation Q3UPL0 803 Y 15592455 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q3UPL0 423 Asymmetric dimethylarginine 24129315 Q3UPL0 526 Phosphoserine 17242355;18630941;19131326;21183079 Q3UPL0 531 Phosphoserine 18630941;21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Sec31a IPI00752849 S 526 SDQVAQpSDGEESP phosphorylation Sec31a IPI00752849 S 531 QSDGEEpSPAAEEQ phosphorylation Sec31a IPI00938457 S 1173 LREQTLpSPTIING phosphorylation Sec31a IPI00938457 S 526 SDQVAQpSDGEESP phosphorylation Sec31a IPI00938457 S 531 QSDGEEpSPAAEEQ phosphorylation Sec31a IPI00938457 S 712 KAQDGSpSPLSLQD phosphorylation Sec31a IPI00938457 T 1175 EQTLSPpTIINGLH phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Sec31a Mus musculus (Mouse) 722; 502; 509; 646; 487; 470; 111; 728; 706; 206; 435; 791 "722,LQDLIEKVVILRK; 502,KEDLGQKIALALN; 509,IALALNKVDGPDV; 646,VESCDLKNWREAL; 487,EEDSRGKYLELLG; 470,SQTEFEKNVWSFL; 111,KIIAGDKEVVIAQ; 728,KVVILRKAVQLTQ; 706,LVACWTKAQDGSS; 206,KNEPIIKVSDHSN; 435,SQVVTEKDFLNRS; 791,LCKAQGKPVSGQE" 722:22790023; 502:22790023; 509:22790023; 646:22790023; 487:22790023; 470:22790023; 111:22790023; 728:22790023; 706:22790023; 206:22790023; 435:22790023; 791:22790023