PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Whsc1 Foxp3 22922362 biogrid exp Whsc1 Sall1 19483677 biogrid,dip exp Whsc1 Eed 24457600 biogrid exp Whsc1 Ogt 19483677 biogrid,dip exp Nanog Whsc1 19483677 biogrid,dip exp Whsc1 Hnrnpu 19483677 biogrid,dip exp Whsc1 Brd4 23921552 intact exp Nkx2-5 Whsc1 19483677 dip exp Sf1 Whsc1 19483677 biogrid,dip exp Whsc1 Sall4 19483677 biogrid,dip exp Hira Whsc1 23921552 intact exp Polr2a Whsc1 19483677 biogrid,dip exp Whsc1 Raver1 19483677 biogrid,dip exp Hdac1 Whsc1 19483677 biogrid,dip exp, ortho Smarca4 Whsc1 19483677 biogrid,dip exp, ortho Mdc1 Whsc1 ortho Whsc1 Zc3h3 ortho Golga3 Whsc1 ortho Ccdc88c Whsc1 ortho Ar Whsc1 ortho Kdm1a Whsc1 ortho Tiam1 Whsc1 ortho Whsc1 Wdr77 ortho Esr1 Whsc1 ortho Whsc1 Ddx20 ortho Rpl8 Whsc1 ortho Hdac2 Whsc1 ortho Whsc1 Rpl14 ortho Sin3a Whsc1 ortho Whsc1 Gemin5 ortho Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Whsc1 ortho Mybbp1a Whsc1 ortho Mdm2 Whsc1 ortho Map1b Whsc1 ortho Ctnnb1 Whsc1 ortho Whsc1 Rbm10 ortho Whsc1 Prpsap2 ortho Trim28 Whsc1 ortho Rplp0 Whsc1 ortho Kif11 Whsc1 ortho Thrap3 Whsc1 ortho Gem (Nuclear organelle) associated protein 4, Protein Gemin4 Whsc1 ortho App Whsc1 ortho Prr11 Whsc1 ortho Whsc1 Skiv2l2 ortho Sin3b Whsc1 ortho Braf Whsc1 ortho Mycbp2 Whsc1 ortho Whsc1 Iqgap1 ortho Whsc1 Rbm4b ortho Whsc1 Plec ortho Whsc1 Whsc1 ortho Ptpn13 Whsc1 ortho Whsc1 Lsm1 ortho Sirt7 Whsc1 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8BVE8 anti tag coimmunoprecipitation 19483677 - C 5 Q8BVE8 tandem affinity purification 19483677 - C 8 Q8BVE8 tandem affinity purification 19483677 - C 7 Q8BVE8 anti bait coimmunoprecipitation 19483677 - C 4 Q8CGY8 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q8CGY8 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q8CGY8 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 O09106 Q8BVE8 anti bait coimmunoprecipitation 19483677 physical association X 2 O09106 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q9ER74 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 Q9ER74 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 Q9ER74 Q8BVE8 anti bait coimmunoprecipitation 19483677 physical association X 2 Q9ER74 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q9ER74 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q8BVE8 Q3TKT4 tandem affinity purification 19483677 physical association X 2 Q8BVE8 Q3TKT4 tandem affinity purification 19483677 physical association X 2 Q8BVE8 Q64213 tandem affinity purification 19483677 physical association X 2 Q8BVE8 anti tag coimmunoprecipitation 19483677 - C 3 P42582 Q8BVE8 anti bait coimmunoprecipitation 19483677 physical association X 2 P42582 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 P42582 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 Q8BX22 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q8BX22 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 Q8BX22 Q8BVE8 anti tag coimmunoprecipitation 19483677 physical association X 2 Q9CW46 Q8BVE8 tandem affinity purification 19483677 physical association X 2 Q8BVE8 O88568 tandem affinity purification 19483677 physical association X 2 Q8BVE8 P08775 tandem affinity purification 19483677 physical association X 2 Q8BVE8 A2RS90 anti bait coimmunoprecipitation 19483677 physical association X 2 Q8BVE8 A2RS90 tandem affinity purification 19483677 physical association X 2 Q8BVE8 A2RS90 anti tag coimmunoprecipitation 19483677 physical association X 2 Q8BVE8 A2RS90 anti tag coimmunoprecipitation 19483677 physical association X 2 Q8BVE8 P54198 anti tag coimmunoprecipitation 23921552 physical association X 2 Q8BVE8 anti bait coimmunoprecipitation 23921552 association C 3

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Nanog Whsc1 MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324103 prey bait Whsc1 Sall4 MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324099 bait prey Hdac1 Whsc1 MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324102 prey bait Whsc1 Raver1 MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324095 bait prey Polr2a Whsc1 MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324100 prey bait Whsc1 Foxp3 MI:0004(affinity chromatography technology) 22922362 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324931 prey bait Smarca4 Whsc1 MI:0415(enzymatic study)|MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_324097|BIOGRID_324091 prey|prey bait|bait Whsc1 Hnrnpu MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324093 bait prey Whsc1 Ogt MI:0415(enzymatic study)|MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_324101|BIOGRID_324094 bait|bait prey|prey Whsc1 Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_331957 prey bait Whsc1 Sall1 MI:0415(enzymatic study)|MI:0415(enzymatic study) 19483677 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_324098|BIOGRID_324092 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality HDAC1 WHSC1 19483677,19483677,19483677 0004,0676,0006 LC POLR2A WHSC1 19483677,19483677 0004,0676 LC NKX2-5 WHSC1 19483677,19483677 0006,0007 LC SMARCA4 WHSC1 19483677,19483677 0004,0676 LC HIRA WHSC1 23921552 0006 LC SF1 WHSC1 19483677,19483677 0004,0676 LC NANOG WHSC1 19483677,19483677,19483677,19483677 0004,0676,0006,0007 LC WHSC1 SALL4 19483677,19483677,19483677 0004,0676,0007 LC WHSC1 OGT 19483677,19483677,19483677 0004,0676,0007 LC WHSC1 HNRNPU 19483677,19483677 0004,0676 LC WHSC1 EED 24457600 0004 LC WHSC1 FOXP3 22922362 0004 LC WHSC1 RAVER1 19483677,19483677 0004,0676 LC WHSC1 SALL1 19483677,19483677,19483677,19483677 0004,0676,0006,0007 LC WHSC1 BRD4 23921552 0006 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8BVE8 O09106 WHSC1 HDAC1 0.21 19483677 Q8BVE8 P08775 WHSC1 POLR2A 0.21 19483677 Q8BVE8 Q3TKT4 WHSC1 SMARCA4 0.21 19483677 Q8BVE8 Q61666 WHSC1 HIRA 0.21 23921552 Q8BVE8 Q71DI3 WHSC1 HIST2H3D 0.309 19483677 Q8BVE8 Q80Z64 WHSC1 NANOG 0.21 19483677 Q8BX22 Q8BVE8 SALL4 WHSC1 0.21 19483677 Q8CGY8 Q8BVE8 OGT WHSC1 0.21 19483677 Q8VEK3 Q8BVE8 HNRNPU WHSC1 0.21 19483677 Q9CW46 Q8BVE8 RAVER1 WHSC1 0.21 19483677 Q9ESU6 Q8BVE8 BRD4 WHSC1 0.21 23921552 Q921E6 Q8BVE8 EED WHSC1 0.126 24457600 Q99JB6 Q8BVE8 FOXP3 WHSC1 0.126 22922362 Q8BVE8 P54198 WHSC1 HIRA 0.21 23921552