PTM - CPLM Gene Name UniProt ID Type Position Code Cd2ap; Mets1 Q9JLQ0 Ubiquitination 71 K Cd2ap; Mets1 Q9JLQ0 Ubiquitination 102 K Cd2ap; Mets1 Q9JLQ0 Ubiquitination 221 K Cd2ap; Mets1 Q9JLQ0 Ubiquitination 457 K Cd2ap; Mets1 Q9JLQ0 Ubiquitination 568 K Cd2ap; Mets1 Q9JLQ0 Ubiquitination 629 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Cd2ap; Mets1 Q9JLQ0 188 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 189 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 193 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 198 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 224 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 229 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 231 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 232 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 233 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 234 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 252 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 380 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 399 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 404 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 458 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 469 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 482 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 510 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 512 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 514 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 527 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 541 Y Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 548 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 549 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 551 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 552 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 563 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 580 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 86 S Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 87 T Mus musculus(Mouse) Cd2ap; Mets1 Q9JLQ0 88 Y Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9JLQ0 S86-p Phosphorylation ASLVQRIstyGLPAG Q9JLQ0 T87-p Phosphorylation SLVQRIstyGLPAGG Q9JLQ0 Y88-p Phosphorylation LVQRIstyGLPAGGI Q9JLQ0 S189-p Phosphorylation VPLTGPTsPLPsPGN Q9JLQ0 S193-p Phosphorylation GPTsPLPsPGNGSEP Q9JLQ0 S224-p Phosphorylation GDIFkEGsVKLRtRt Q9JLQ0 T229-p Phosphorylation EGsVKLRtRtsssET Q9JLQ0 T231-p Phosphorylation sVKLRtRtsssETEE Q9JLQ0 S232-p Phosphorylation VKLRtRtsssETEEK Q9JLQ0 S233-p Phosphorylation KLRtRtsssETEEKK Q9JLQ0 S234-p Phosphorylation LRtRtsssETEEKKT Q9JLQ0 T254-p Phosphorylation LQPLGSRtQNVEVTK Q9JLQ0 S380-p Phosphorylation SLLEQKPsKPAAPQV Q9JLQ0 S404-p Phosphorylation KASNLLRsPGAVYPK Q9JLQ0 S458-p Phosphorylation QLPVRPksVDLDAFV Q9JLQ0 S510-p Phosphorylation GRFNGGHsPtQsPEK Q9JLQ0 T512-p Phosphorylation FNGGHsPtQsPEKTL Q9JLQ0 S514-p Phosphorylation GGHsPtQsPEKTLKL Q9JLQ0 S527-p Phosphorylation KLPKEDDsGNLKPLE Q9JLQ0 Y541-p Phosphorylation EFKKDASySSKSSLs Q9JLQ0 S548-p Phosphorylation ySSKSSLstPssASK Q9JLQ0 T549-p Phosphorylation SSKSSLstPssASKV Q9JLQ0 S551-p Phosphorylation KSSLstPssASKVNT Q9JLQ0 S552-p Phosphorylation SSLstPssASKVNTA Q9JLQ0 T563-p Phosphorylation VNTAAFLtPLELkAK Q9JLQ0 S580-p Phosphorylation ADDGKRNsVDELRAQ Q9JLQ0 K71-ub Ubiquitination KDDNLPIkRERQGNV Q9JLQ0 K102-ub Ubiquitination IQPHPQTkAIKKKTK Q9JLQ0 K221-ub Ubiquitination IGFGDIFkEGsVKLR Q9JLQ0 K457-ub Ubiquitination EQLPVRPksVDLDAF Q9JLQ0 K568-ub Ubiquitination FLtPLELkAKAEADD Q9JLQ0 K629-ub Ubiquitination NLEVEIAkLKKAVLL

PTM - dbPTM UniProt ID Position Code Type Resources References Q9JLQ0 458 S Phosphorylation Swiss-Prot 1010711 19144319 Q9JLQ0 458 S Phosphorylation PhosphoELM.10011 19144319 Q9JLQ0 189 S Phosphorylation Phosphositeplus.1010730 21659605 Q9JLQ0 193 S Phosphorylation Phosphositeplus.1010730 21659605;22067460 Q9JLQ0 224 S Phosphorylation Phosphositeplus.1010730 21183079 Q9JLQ0 233 S Phosphorylation Phosphositeplus.1010730 20139300;21659605 Q9JLQ0 380 S Phosphorylation Phosphositeplus.1010730 22067460 Q9JLQ0 404 S Phosphorylation Phosphositeplus.1010730 17242355;18846507;21183079;21659604;21659605;22067460 Q9JLQ0 458 S Phosphorylation Phosphositeplus.1010730 18846507;19144319;19367708;19854140;20139300;20415495;20531401;21183079;21659604;21659605;22067460 Q9JLQ0 510 S Phosphorylation Phosphositeplus.1010730 18846507;19854140;20139300;20531401;21183079;21659604;21659605;22067460 Q9JLQ0 514 S Phosphorylation Phosphositeplus.1010730 20139300;21183079;21659604;21659605 Q9JLQ0 527 S Phosphorylation Phosphositeplus.1010730 22067460 Q9JLQ0 580 S Phosphorylation Phosphositeplus.1010730 18846507;20139300 Q9JLQ0 231 T Phosphorylation Phosphositeplus.1010730 20139300 Q9JLQ0 512 T Phosphorylation Phosphositeplus.1010730 20139300 Q9JLQ0 563 T Phosphorylation Phosphositeplus.1010730 22067460 Q9JLQ0 88 Y Phosphorylation Phosphositeplus.1010730 21183079

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9JLQ0 458 S 19144319 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9JLQ0 224 Phosphoserine 21183079 Q9JLQ0 458 Phosphoserine 19144319;21183079 Q9JLQ0 510 Phosphoserine 21183079 Q9JLQ0 514 Phosphoserine 21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Cd2ap IPI00268688 S 404 ASNLLRpSPGAVYP phosphorylation Cd2ap IPI00268688 S 458 LPVRPKpSVDLDAF phosphorylation Cd2ap IPI00268688 S 469 AFVARNpSKETDDV phosphorylation Cd2ap IPI00268688 S 482 NFDDIApSSENLLH phosphorylation Cd2ap IPI00268688 S 510 RFNGGHpSPTQSPE phosphorylation Cd2ap IPI00268688 S 540 EFKKDApSYSSKPS phosphorylation Cd2ap IPI00268688 S 548 SSKPSLpSTPSSAS phosphorylation Cd2ap IPI00268688 S 580 DDGKKNpSVDELRA phosphorylation Cd2ap IPI00268688 S 86 SLVQRIpSTYGLPA phosphorylation Cd2ap IPI00268688 T 87 LVQRISpTYGLPAG phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Cd2ap Mus musculus (Mouse) 71; 221; 102; 457; 629; 568 "71,DDNLPIKRERQGN; 221,GFGDIFKEGSVKL; 102,QPHPQTKAIKKKT; 457,QLPVRPKSVDLDA; 629,LEVEIAKLKKAVL; 568,LTPLELKAKAEAD" 71:22790023; 221:22790023; 102:22790023; 457:22790023; 629:22790023; 568:22790023