PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ubr4 Eed 24457600 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Ywhae 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Rpgrip1l 21565611 intact exp Ubr4 Sart3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Nck1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Cdkn1a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Kcmf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Pnpla1 ortho Ubr4 Rad23b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Emid1 ortho G G G G G G G G G G G G G G G G G G G Ubr4 Mov10 ortho G G G G G G G G G G G G G G G G G G G G Ubr4 Ctps1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Birc2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Ecm29 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Gh1 ortho G G G G Ubr4 Zeb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Rb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Faf2 ortho P Ubr4 Ubxn7 ortho P Ubr4 Sox2 ortho G G G G G G G G G G G Ubr4 Rap1b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Shfm1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Vim ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Aurkb ortho G G G G G G G G G G G G G Ubr4 Sass6 ortho G G G G G G G G G G G G G Ubr4 Stat2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Acly ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Ppp1cb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Faf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Figf ortho G G G G G G G G G G G G Ubr4 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Psmc6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Birc3 ortho G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Vcp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Rangap1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Cep57 ortho Ubr4 Chia ortho P G G G G G G G Ubr4 Eftud2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Egfr ortho GP G G G G G G G G G G G G G G G G G Ubr4 Lars ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Cep250 ortho Ubr4 Aar2 ortho G G G G G G G G G G G G Ubr4 Psmd13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Eif5b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Cd96 ortho G G G G G G Ubr4 Foxk2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Tubgcp3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Rad23a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Usp9x ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Prmt6 ortho G G G G G G G G G Ubr4 Mob4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Usf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Hspd1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Grb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Itga4 ortho G G G G Ubr4 Serine hydroxymethyltransferase ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Foxk1 ortho P G G G Ubr4 Ddx46 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Ccdc19 protein, Coiled-coil domain containing 19, MCG117653, Protein Cfap45 ortho Ubr4 Psmd14 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Flnb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Tp53 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Xrcc3 ortho Ubr4 Ubxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Mcrs1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Prpf40a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Spata1 ortho Ubr4 Ube2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Ubc ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Sirt7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Psmc5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Srpk2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Vcam1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Sbno1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Poglut1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Snrnp200 ortho P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A2AN08 Q921E6 affinity chromatography technology 24457600 physical association X 2 A2AN08 cosedimentation 16615898 colocalization C 1216 A2AN08 cosedimentation 16615898 colocalization C 1216 P06933 A2AN08 coimmunoprecipitation 16081543 physical association X 2 P06933 A2AN08 affinity chromatography technology 16081543 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality UBR4 YWHAE 16615898 0027 LC UBR4 PGLS 16615898 0027 LC UBR4 RPGRIP1L 21565611 0007 HT UBR4 NPHS2 26792178 0004 LC UBR4 EED 24457600 0004 LC UBR4 IFT27 26885862 0676 LC UBR4 CHAF1A 26365490 0004 LC