PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Aup1 Numbl 18299187 biogrid exp Aup1 Ubc 22871113 biogrid exp, ortho Aup1 Protein Rnf139, RCG60186 ortho G G G G G G G G Aup1 Ntrk1 ortho Aup1 Tctn2 ortho G G G G G G G G Aup1 Itgam ortho G Aup1 RGD1308918_predicted ortho G G G G G G G G Aup1 Tmem17 ortho Aup1 Hsd3b7 ortho G G G G G G G G Aup1 Protein Surf4, Surfeit 4, isoform CRA_a ortho G G G G G G G G Aup1 Battenin ortho Aup1 Vcp ortho G G G G G G G G Aup1 Kcnd3 ortho G G G G Aup1 Rpn2 ortho G G G G G G G G Aup1 Rnf114 ortho G G G G G G G G Aup1 Ube2g2_predicted ortho G G G G G G G G Aup1 Ubl4a ortho G G G G G G G G Aup1 Protein Stt3b, RCG25591, isoform CRA_a, RGD1311563 protein ortho G G G G G G G G Aup1 Oprd1 ortho G Aup1 Ddost ortho G G G G G G G G Aup1 Brf2 ortho G G Aup1 Pcmtd2_predicted ortho G G G G G G G G Aup1 Ilk ortho G G G G G G G G Aup1 Protein Syvn1, Syvn1 protein ortho Aup1 Mdc1 ortho G Aup1 Os9 ortho G G G G G G G G Aup1 Apob ortho G G G G Aup1 Tmem248 ortho G G G G G G G G Aup1 LOC498962 ortho G G G G G G G G Aup1 Tmem216 ortho G G G G G G G Aup1 Slc38a1 ortho G G G G G G Aup1 Ywhae ortho G G G G G G G G Aup1 Protein Ckap5 ortho G G G G G G G G Aup1 Hmgcr ortho G G G G G G G G Aup1 Fbxo6 ortho G G G G G G G G Aup1 Tubg1 ortho G G G G G G G G Aup1 Sptlc1_predicted ortho G G G G G G G G Aup1 Atg12 ortho G G G G G G G G Aup1 Faf2 ortho Aup1 Ndn ortho G G G G G Aup1 Aup1 ortho G G G G G G G G Aup1 Oprk1 ortho G G G Aup1 Itga1 ortho G G G G G Aup1 Ube2e3_predicted ortho G G G G G G G G Aup1 Sel1l ortho G G G G G G G G Aup1 Lpcat1 ortho G G G G G G G Aup1 Oprm1 ortho G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Aup1 Numbl MI:0018(two hybrid) 18299187 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_333697 prey bait Ubc Aup1 MI:0004(affinity chromatography technology) 22871113 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_336229 bait prey

PPI - HINT Gene A Gene B PMID Method Quality AUP1 NUMBL 18299187 0004 LC