PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Trpv1 Faf1 16510717 biogrid exp G Ubc Faf1 22871113 biogrid exp, ortho RelA Faf1 ortho G G G G G G G G Faf1 Ctnnb1 ortho G G G G G G G G Bag6 Faf1 ortho G G G G G G Taf1d Faf1 ortho Ubl4a Faf1 ortho G G G G G G G G fadd Faf1 ortho Faf1 Ikbkb ortho G G G G G G G G Ntrk1 Faf1 ortho Dnaja1 Faf1 ortho G G G G G G G G Hspa8 Faf1 ortho Chm Faf1 ortho Faf1 Nploc4 ortho G G G G G G G G Trove2_predicted Faf1 ortho CD40 molecule, TNF receptor superfamily member 5, Protein Cd40, Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a Faf1 ortho Klhl22 Faf1 ortho G G G G G G G G Ddost Faf1 ortho G G G G G G G G LOC682908 protein, Protein Rcc1, RCG31301, isoform CRA_a Faf1 ortho Protein Rad23a, RAD23 homolog A (S. cerevisiae) Faf1 ortho G G G G G Protein Nlrp3 Faf1 ortho Csnk2b Faf1 ortho G G G G G G G G Phosphoribosylglycinamide formyltransferase, isoform CRA_a, Protein Gart Faf1 ortho G G G G G G G Hsd17b10 Faf1 ortho G G G G G G G G Tk1 Faf1 ortho G G G G G G G G Protein Tln1, RCG55135, isoform CRA_b Faf1 ortho G G G G G G G G Anxa6 Faf1 ortho G G G G G G G G Hif1a Faf1 ortho G G G G G G G G Tnnt1 Faf1 ortho Prpsap2 Faf1 ortho G G G G G G G G Nudt21 Faf1 ortho G G G G G G G G Fas Faf1 ortho Dnajb11 Faf1 ortho G G G G G G G G Igf2 Faf1 ortho G G G G G Hist1h4b, Hist1h4m, Hist4h4 Faf1 ortho G G G G G Plaa Faf1 ortho G G G G G G G G Faf1 Ufd1l ortho G G G G G G G G Cul3 Faf1 ortho G G G G G G G G Protein Ugp2, UDP-glucose pyrophosphorylase 2, UDP-glucose pyrophosphorylase 2, isoform CRA_b Faf1 ortho G G G G G G G G Intestinal-type alkaline phosphatase 2, IAP-2, Intestinal alkaline phosphatase 2 Faf1 ortho Faf1 Vapb ortho G G G G G G G G Ubr4 Faf1 ortho G G G G G G G G Nr4a1 Faf1 ortho G G G G G G G G Cyclin-dependent kinase inhibitor 1A, Cyclin-dependent kinase inhibitor 1A (P21, Cip1), P21, P21 protein, Protein Cdkn1a Faf1 ortho G G G G G G G Ngly1 Faf1 ortho Cul2_predicted Faf1 ortho G G G G G Ppm1g Faf1 ortho G G G G G G G G Carm1 Faf1 ortho G G G G G G G G Swap70_predicted Faf1 ortho Hirip3 Faf1 ortho G G G G G G G Rpl24 Faf1 ortho G G G G G G G G ATPase Asna1 Faf1 ortho G G G G G G G Faf1 Vapa ortho G G G G G G G G Protein Ranbp3, RCG44996, isoform CRA_c Faf1 ortho G G G G G G G G Rpn2 Faf1 ortho G G G G G G G G Faf2 Faf1 ortho Protein G3bp1 Faf1 ortho G G G G G G G G Protein Sirt6, Sirtuin 6 (Silent mating type information regulation 2, homolog) 6 (S. cerevisiae), Sirtuin 6 (Silent mating type information regulation 2, homolog) 6 (S. cerevisiae), isoform CRA_a Faf1 ortho G Faf1 Ilk ortho G G G G G G G G Tceal1 Faf1 ortho Pja2 Faf1 ortho G G G G G G G G Protein Skil Faf1 ortho Protein Nlrp10, RCG39438 Faf1 ortho LOC100360260 Faf1 ortho Set Faf1 ortho G G G G G G G G Eed_predicted Faf1 ortho G G G G G G G G Prmt3 Faf1 ortho Farslb Faf1 ortho G G G G G G G G Hspa4 Faf1 ortho G G G G G G G G Rap1a Faf1 ortho G G G G G G G G Vcp Faf1 ortho G G G G G G G G Ubr1 Faf1 ortho G G G G G G G G Cul1_predicted Faf1 ortho G G G G G G G G Urod Faf1 ortho G G G G G G G G Vcpip1 Faf1 ortho Cdc73 Faf1 ortho Cdc5l Faf1 ortho G G G G G G G G Magix Faf1 ortho Plod2 Faf1 ortho G G G G G G G G Nr1h2 Faf1 ortho G G G G G G G G Sec23a_predicted Faf1 ortho Skp1 Faf1 ortho G G G G G G G G Faf1 Casp8 ortho G Hsph1 Faf1 ortho G G G G G G G G RGD1311660_predicted Faf1 ortho G G G G G G G G Tsc22d1 Faf1 ortho G G G G G G G G Ubr2 Faf1 ortho G G G G G G G G Btrc Faf1 ortho G G G G G G G G Csnk2a1 Faf1 ortho Rae1 Faf1 ortho Anxa1 Faf1 ortho G G G G G G G G Faf1 Faf1 ortho G G G G G G G G Cars_predicted Faf1 ortho G G G G G G G G Itgb1bp1_predicted Faf1 ortho G G G G G G G G Rap1b Faf1 ortho G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q63429 Q924K2 affinity chromatography technology 22871113 physical association X 2 Q924K2 O35433 pull down 16510717 direct interaction X 2 Q924K2 O35433 affinity chromatography technology 16510717 physical association X 2 Q924K2 O35433 affinity chromatography technology 16510717 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q924K2 O35433 FAF1 TRPV1 0.569 16510717 Q924K2 Q63429 FAF1 UBC 0.126 22871113