PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus kel CG2813-PA, Coiled, isoform B, LD16147p 25294943 intact exp G G G kel Cfp1 14605208 biogrid,i2d,mint,intact exp G G G kel Grip71 i2d exp kel LD42058p, Short spindle 2, isoform A, Short spindle 2, isoform C 14605208 biogrid,i2d exp G G G Pen kel 14605208 biogrid,i2d,mint,intact exp kel Grip71 14605208 biogrid,mint,intact exp CG8642 kel 14605208 biogrid,intact exp kel Cullin 3, isoform F, FI19425p1 20065088 biogrid exp, ortho G G G kel kel 14605208 intact exp, ortho G G G Galphai kel ortho G G G Galphao kel ortho G G G kel Roc1a ortho G G G kel FI11917p, KEAP1, Keap1, isoform B ortho G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q04652 Q9W352 two hybrid 14605208 direct interaction X 2 Q04652 Q8IP45 affinity chromatography technology 20065088 physical association X 2 Q04652 two hybrid 14605208 direct interaction X 2 Q04652 two hybrid 14605208 direct interaction X 2 O76521 Q04652 two hybrid 14605208 direct interaction X 2 Q04652 two hybrid 14605208 direct interaction X 2 Q04652 Q9W352 two hybrid 14605208 physical association X 2 A1Z7G6 Q04652 two hybrid 14605208 physical association X 2 Q9VJ57 Q04652 two hybrid 14605208 physical association X 2 O76521 Q04652 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B kel CG8642 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0465(dip)|(biogrid) UniProt_63320|DIP_25410|BIOGRID_47317 bait|-|bait prey|-|prey kel CG17446 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|(intact)|(biogrid)|MI:0471(mint) DIP_17811|UniProt_55764|BIOGRID_42138|MINT_10040 -|bait|prey|bait -|prey|bait|prey kel ssp2 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_47318 bait prey kel Grip71 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|(biogrid) MINT_21901|UniProt_58599|BIOGRID_29878 bait|bait|prey prey|prey|bait kel Grip71 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_6525 - - kel Q8IQK5 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_17064|UniProt_63321 bait|bait prey|prey Kap-alpha1 kel MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0465(dip) UniProt_63319|MINT_17062|BIOGRID_47316|DIP_25409 prey|prey|prey|- bait|bait|bait|- kel Q9V4V7 MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_17063 bait prey kel Cul-3 MI:0004(affinity chromatography technology) 20065088 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_64135 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04652 O76521 KEL KAP-ALPHA1 0.183 14605208 Q86LC4 Q04652 GRIP71 KEL 0.033 14605208 Q9W352 Q04652 CFP1 KEL 0.332 14605208 Q9VJ57 Q04652 GRIP71 KEL 0.183 14605208 Q9VPR7 Q04652 COLD KEL 0.126 25294943 Q04652 A1Z7G6 KEL A1Z7G6 0.183 14605208