PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Chi-RB CG4570, CG4570 protein, CG4570-PA, LD02192p 14605208 biogrid,i2d,mint,intact exp G Chi-RB CG10418-PA 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G pnr Chi-RB unassigned4 intact exp G bcd Chi-RB unassigned4 intact exp G su(Hw) Chi-RB unassigned4 intact exp G G G G G G G G G G Chi-RB CG5618, isoform A, LP10922p 14605208 biogrid,i2d,mint,intact exp G G G G G G G G AT10229p, CG11165 Chi-RB 14605208 biogrid,intact exp G G Chi-RB AT17667p, CG15177, isoform A 14605208 biogrid,i2d,mint,intact exp G Chi-RB CG32105, isoform B, RE70810p 14605208 biogrid,i2d,mint,intact exp G G Chi-RB CG15578, IP03615p 14605208 biogrid,i2d,mint,intact exp G Chi-RB CG32819-RB 14605208 biogrid,i2d,mint,intact exp Chi-RB RE70568p i2d exp ftz Chi-RB unassigned4 intact exp oc Chi-RB unassigned4 intact exp G G G Chi-RB lola 14605208 biogrid,i2d,mint,intact exp G G Chi-RB CG4328-RA 14605208 biogrid,i2d,mint,intact exp G G Chi-RB CG11275, FI01029p 14605208 biogrid,i2d,mint,intact exp G G G G G G G Lcp2 Chi-RB 14605208 biogrid,i2d,mint,intact exp GH01724p, p47 Chi-RB 14605208 biogrid,intact exp G G G G G G G G G G lola Chi-RB i2d exp Chi-RB AT25102p, Tektin C, isoform A, Tektin C, isoform C, Tektin C, isoform D 14605208 biogrid,i2d,mint,intact exp G Chi-RB Mitochondrial ribosomal protein L38, RE63629p 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G CG4836, isoform E Chi-RB 14605208 biogrid,i2d,mint,intact exp G Lim3, isoform G Chi-RB 14605208 biogrid,i2d,mint,intact exp G G G G SCP2 Chi-RB 14605208 biogrid,i2d,mint,intact exp G G G G Chi-RB CG10619-PA, isoform A, Tailup, isoform C 14605208 biogrid,i2d,mint,intact exp, ortho G G G Chi-RB CG5708, isoform B, CG5708, isoform C, CG5708-PA, isoform A, LD11652p 14605208 biogrid,i2d,mint,intact exp, ortho G G G G G G G G G G Beadex, isoform D Chi-RB 22036573 biogrid exp, ortho G G G G G G G Ssdp Chi-RB 14605208,22036573 biogrid,i2d,mint,intact exp, ortho G G G G G G G G G ap Chi-RB unassigned4,14605208 biogrid,i2d,mint,intact exp, ortho G G G G G Chi-RB DLim1, GH04929p, Lim1, isoform A 14605208 biogrid,i2d,mint,intact exp, ortho G G G Chi-RB Su(dx) ortho G G G G G G G G G Chi-RB Trax-RB ortho G G G G G G G G G G Fak56D Chi-RB ortho G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VTW6 Q7KVG9 - 14605208 - X 2 Q9VI39 Q7KVG9 - 14605208 - X 2 Q7KVG9 P42284-1 - 14605208 - X 2 Q7KVG9 Q9VY48 - 14605208 - X 2 Q7KVG9 Q7K3Z3 - 14605208 - X 2 Q7KVG9 - 14605208 - X 2 Q9V472 Q7KVG9 - 14605208 - X 2 Q7KVG9 Q8MRL0 - 14605208 - X 2 Q7KVG9 P07187 - 14605208 - X 2 Q9VEB9 Q7KVG9 - 14605208 - X 2 Q9W4L6 Q7KVG9 - 14605208 - X 2 Q9W279 Q7KVG9 - 14605208 - X 2 Q7KVG9 - 14605208 - X 2 Q9VJ37 Q7KVG9 - 14605208 - X 2 Q7KVG9 Q7K049 - 14605208 - X 2 Q7KVG9 Q9VJ00 - 14605208 - X 2 Q7KVG9 Q9VTW5 - 14605208 - X 2 Q7KVG9 Q8T3Z0 - 14605208 - X 2 Q7KVG9 O16158 - 14605208 - X 2 Q7KVG9 P29673 - 14605208 - X 2 Q7KVG9 Q9VPH6 - 14605208 - X 2 Q9VGV7 Q7KVG9 - 14605208 - X 2 Q9VL21 Q7KVG9 - 14605208 - X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Scp2 Chi MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_40592 bait prey CG11165 Chi MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_36072 bait prey Chi CG17450 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_48518 prey bait Lcp2 Chi MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_45364 prey bait Chi tup MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_30024 prey bait Chi Lim1 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_30413 prey bait Chi Tektin-C MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_34987 prey bait p47 Chi MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_30258 bait prey Chi CG4836 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_45361 bait prey ap Chi MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_33147 prey bait Chi mRpL38 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_41459 prey bait Chi CG32105 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_44541 prey bait Chi CG4328-RA MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_33144 bait prey Chi CG15578 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_31961 prey bait Chi CG4570 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_33145 bait prey Chi Ssdp MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 14605208,22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_45363|BIOGRID_67144 bait|prey prey|bait Chi CG5618 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_45362 bait prey Chi CG5708 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_33146 bait prey lola Chi MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_30703 bait prey Chi CG32819 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_48519 prey bait