PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Elongin-B AT25465p, CG6380, isoform B, CG6380-PA 14605208 biogrid,i2d,mint,intact exp G Elongin-B Homer, isoform E 14605208 biogrid,i2d,mint,intact exp G G G G G Spinophilin, isoform J Elongin-B 25294943 intact exp G G G G G G Elongin-B PPP5 25294943 intact exp G G G G G G G G G G Elongin-B Arginine methyltransferase 8, RE49877p 22036573 biogrid exp G G G G G G Elongin-B Neu3 25294943 intact exp Elongin-B CG12081, isoform A, CG12081, isoform B, LD20420p 22036573 biogrid exp G G G G G G G G G G Elongin-B Elongin C, isoform A, Elongin C, isoform B, RE05591p, RH71704p 19079254,14605208,22036573 biogrid,intact exp, ortho G G G G G G G G G G Elongin-B 14-3-3epsilon ortho G G G G G G G G G G Elongin-B Nuclear receptor-binding protein homolog ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O44226 Q7JWD6 - 14605208 - X 2 Q9VM94 O44226 - 14605208 - X 2 O44226 Q9VJE7 - 14605208 - X 2 Q9W3D5 O44226 affinity chromatography technology 22036573 physical association X 2 O44226 Q7JWD6 two hybrid 14605208 direct interaction X 2 O44226 Q7JWD6 affinity chromatography technology 22036573 physical association X 2 O44226 M9PB54 two hybrid 14605208 direct interaction X 2 O44226 Q9VJE7 two hybrid 14605208 direct interaction X 2 Q8SX32 O44226 affinity chromatography technology 22036573 physical association X 2 O44226 Q7JWD6 two hybrid 14605208 physical association X 2 Q9VM94 O44226 two hybrid 14605208 physical association X 2 O44226 Q9VJE7 two hybrid 14605208 physical association X 2 O44226 Q7JWD6 two hybrid 14605208 physical association X 2 O44226 Q7JWD6 two hybrid 14605208 physical association X 2 O44226 Q7JWD6 two hybrid array 19079254 physical association X 2 O96607 O44226 two hybrid 14605208 physical association X 2 O44226 Q9VJE7 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Elongin-B Elongin-C MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 14605208,19079254,22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|(intact)|(intact)|(biogrid) UniProt_50355|DIP_23164|BIOGRID_33218|UniProt_43460|UniProt_50354|BIOGRID_65585 prey|-|bait|prey|bait|prey bait|-|prey|bait|prey|bait Elongin-B homer MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_55069|MINT_24223 bait|bait prey|prey Elongin-B CG12081 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_70193 bait prey Elongin-B CG6380 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_45649|MINT_14938|UniProt_50353 bait|prey|prey prey|bait|bait Elongin-B Q9V8V2 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_14939|MINT_14940 prey|bait bait|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VM94 O44226 HOMER ELOB 0.033 14605208 Q6QU65 O44226 MELTRIN {ECO:0000313|FLYBASE:FBGN0265140} ELOB 0.126 25294943 O96607 O44226 HOMER ELOB 0.183 14605208 Q7JWD6 O44226 ELOC ELOB 0.507 19079254,14605208 Q9VH81 O44226 Q9VH81 ELOB 0.126 25294943 Q9VJE7 O44226 Q9VJE7 ELOB 0.21 14605208 O44226 M9NFI9 ELOB M9NFI9 0.126 25294943