PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5 14605208 biogrid,intact exp G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p CG10032 14605208 biogrid,intact exp CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p Arpc2 ortho G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p Arpc4 ortho G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p CG12099, isoform A, CG12099, isoform B, LD09551p ortho G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p CG5203-PA, Carboxy terminus of Hsp70-interacting protein, RE01069p ortho G G G G G G G G G Act5C CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p ortho G G G G G G G G G IP10364p, Rrp42 CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p ortho G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p GH24511p, Ubiquitin activating enzyme 1, isoform A ortho G G G G G G G G G Iap2 CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p ortho G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p ortho G G G G G G G G G Myo61F CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p ortho G G G G G cpb CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p ortho G G G G G G G G G CG2924, isoform A, CG2924, isoform B, CG2924, isoform D, CG2924, isoform E, LD28546p csul ortho G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q29R09 Q9VYY3 - 14605208 - X 2 Q9VI89 Q29R09 - 14605208 - X 2 Q29R09 Q9VYY3 two hybrid 14605208 direct interaction X 2 Q9VI89 Q29R09 two hybrid 14605208 direct interaction X 2 Q29R09 Q9VYY3 two hybrid 14605208 physical association X 2 Q9VI89 Q29R09 two hybrid 14605208 physical association X 2 Q29R09 Q9VYY3 two hybrid 14605208 physical association X 2 Q9VI89 Q29R09 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG2924 CG10032 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_57571|BIOGRID_33982 prey|prey bait|bait CG2924 CG1749 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|(biogrid) DIP_17900|UniProt_55831|BIOGRID_32278 -|bait|prey -|prey|bait