PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG5846, LP07441p CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp G G G HLHm7 CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp Arr1 CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp G G Hsp60B CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp CG8924, LD19131p CG13708, isoform A, CG13708, isoform B 14605208 biogrid,i2d,mint,intact exp CG8924, LD19131p CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp G G G CG8924, LD19131p Cfp1 14605208 biogrid,i2d,mint,intact exp G G G CG11327-RA CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp CG8924, LD19131p tamo 14605208 biogrid,i2d,mint,intact exp G G G CG8924, LD19131p CG18292-RA 14605208 biogrid,i2d,mint,intact exp G G G RE32936p, SET and MYND domain protein 4 CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp Elongin C, isoform A, Elongin C, isoform B, RE05591p, RH71704p CG8924, LD19131p 14605208 biogrid,intact exp G G G CG8924, LD19131p CG3726, isoform B 14605208 biogrid,i2d,mint,intact exp G G G PAB-dependent poly(A)-specific ribonuclease subunit PAN3 CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp G G G CG15218-PA, isoform A, Cyclin K, isoform B, Cyclin K, isoform C, LD21709p CG8924, LD19131p 14605208 biogrid,i2d,mint,intact exp G G G AT09434p CG8924, LD19131p i2d exp Dorsal interacting protein 3, RE40480p CG8924, LD19131p 14605208 biogrid,intact exp G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VXL5 Q9VXL5 - 14605208 - X 2 Q9VL58 Q9VXL5 - 14605208 - X 2 Q961D1 Q9VXL5 - 14605208 - X 2 Q8SWW7 Q9VXL5 - 14605208 - X 2 Q7JWD6 Q9VXL5 - 14605208 - X 2 Q9VZ81 Q9VXL5 - 14605208 - X 2 Q7JZD5 Q9VXL5 - 14605208 - X 2 B7YZS3 Q9VXL5 - 14605208 - X 2 Q9I7T8 Q9VXL5 - 14605208 - X 2 Q9VXL5 Q9W352 - 14605208 - X 2 Q9VM98 Q9VXL5 - 14605208 - X 2 M9NES0 Q9VXL5 - 14605208 - X 2 Q9VZ27 Q9VXL5 - 14605208 - X 2 Q9VPS5 Q9VXL5 - 14605208 - X 2 P13097 Q9VXL5 - 14605208 - X 2 Q9VTX2 Q9VXL5 - 14605208 - X 2 Q9VXL5 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VXL5 A8JNJ2 two hybrid 14605208 direct interaction X 2 Q9VL58 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q961D1 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q8SWW7 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q7JWD6 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VZ81 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q7JZD5 Q9VXL5 two hybrid 14605208 direct interaction X 2 B7YZS3 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VXL5 Q9W352 two hybrid 14605208 direct interaction X 2 Q9VM98 Q9VXL5 two hybrid 14605208 direct interaction X 2 M9NES0 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VZ27 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VPS5 Q9VXL5 two hybrid 14605208 direct interaction X 2 P13097 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VTX2 Q9VXL5 two hybrid 14605208 direct interaction X 2 Q9VL58 Q9VXL5 two hybrid 14605208 physical association X 2 Q961D1 Q9VXL5 two hybrid 14605208 physical association X 2 Q8SWW7 Q9VXL5 two hybrid 14605208 physical association X 2 Q7JWD6 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VZ81 Q9VXL5 two hybrid 14605208 physical association X 2 Q7JZD5 Q9VXL5 two hybrid 14605208 physical association X 2 B7YZS3 Q9VXL5 two hybrid 14605208 physical association X 2 Q95RR8 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VXL5 Q9W352 two hybrid 14605208 physical association X 2 Q9VXL5 Q9VXL5 two hybrid 14605208 physical association Y 1 Q9VM98 Q9VXL5 two hybrid 14605208 physical association X 2 M9NES0 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VZ27 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VPS5 Q9VXL5 two hybrid 14605208 physical association X 2 P13097 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VTX2 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VXL5 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VL58 Q9VXL5 two hybrid 14605208 physical association X 2 Q961D1 Q9VXL5 two hybrid 14605208 physical association X 2 Q8SWW7 Q9VXL5 two hybrid 14605208 physical association X 2 Q7JWD6 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VZ81 Q9VXL5 two hybrid 14605208 physical association X 2 Q7JZD5 Q9VXL5 two hybrid 14605208 physical association X 2 B7YZS3 Q9VXL5 two hybrid 14605208 physical association X 2 Q95RR8 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VXL5 Q9W352 two hybrid 14605208 physical association X 2 Q9VM98 Q9VXL5 two hybrid 14605208 physical association X 2 M9NES0 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VZ27 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VPS5 Q9VXL5 two hybrid 14605208 physical association X 2 P13097 Q9VXL5 two hybrid 14605208 physical association X 2 Q9VTX2 Q9VXL5 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Hsp60B CG8924 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0465(dip)|(intact) MINT_11978|BIOGRID_43564|DIP_19991|UniProt_25705 bait|bait|-|bait prey|prey|-|prey CG5846 CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|(intact)|(biogrid)|MI:0471(mint) DIP_24685|UniProt_62576|BIOGRID_46769|MINT_16377 -|bait|bait|bait -|prey|prey|prey CG11327-RA CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|MI:0471(mint)|(intact) BIOGRID_36527|DIP_9094|MINT_24329|UniProt_55177 bait|-|bait|bait prey|-|prey|prey CG3726 CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact)|MI:0471(mint) BIOGRID_45222|DIP_22589|UniProt_49791|MINT_14388 bait|-|bait|bait prey|-|prey|prey CG17446 CG8924 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) UniProt_55766|MINT_10042|DIP_17813|BIOGRID_42140 bait|bait|-|bait prey|prey|-|prey Q9V8V2 CG8924 MI:0398(two hybrid pooling approach) 14605208 taxid:0() taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0471(mint) MINT_17685 bait prey tamo CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip)|MI:0471(mint) BIOGRID_45535|UniProt_50196|DIP_23010|MINT_14784 bait|bait|-|bait prey|prey|-|prey Smyd4 CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact)|MI:0471(mint) BIOGRID_39711|DIP_14096|UniProt_47413|MINT_29037 bait|-|bait|bait prey|-|prey|prey CycK CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0465(dip)|MI:0471(mint)|(biogrid) UniProt_59885|DIP_15915|MINT_8245|BIOGRID_40900 bait|-|bait|bait prey|-|prey|prey CG11486 CG8924 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_30463 bait prey HLHm7 CG8924 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0465(dip)|(biogrid)|(intact) MINT_17545|DIP_25893|BIOGRID_47668|UniProt_53147 bait|-|bait|bait prey|-|prey|prey CG8924 CG13708 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|MI:0471(mint)|(intact)|(biogrid) DIP_13483|MINT_28450|UniProt_52799|BIOGRID_31331 -|prey|prey|prey -|bait|bait|bait CG8924 CG18292-RA MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_56628|DIP_18701|BIOGRID_42716|MINT_10852 prey|-|prey|prey bait|-|bait|bait CG11486 CG8924 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|MI:0465(dip) MINT_24680|UniProt_63537|DIP_9475 bait|bait|- prey|prey|- Arr1 CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_62493|DIP_24604|BIOGRID_46722|MINT_16295 bait|-|bait|bait prey|-|prey|prey Elongin-C CG8924 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|(biogrid) DIP_26038|UniProt_53298|BIOGRID_47783 -|bait|prey -|prey|bait Dip3 CG8924 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_51126|BIOGRID_38166 bait|bait prey|prey Q9V8C0 CG8924 MI:0398(two hybrid pooling approach) 14605208 taxid:0() taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0471(mint) MINT_26830 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VXL5 Q95RR8 Q9VXL5 Q95RR8 0.21 14605208 Q9VXL5 P13097 Q9VXL5 HLHM7 0.21 14605208 Q9VXL5 Q9VPS5 Q9VXL5 HSP60B 0.21 14605208 Q9VXL5 P15372 Q9VXL5 ARR1 0.21 14605208 Q9VXL5 Q7JWD6 Q9VXL5 ELOC 0.183 14605208 Q9VXL5 Q7JZD5 Q9VXL5 DIP3 0.183 14605208 Q9VXL5 Q8SWW7 Q9VXL5 Q8SWW7 0.183 14605208 Q9VXL5 Q961D1 Q9VXL5 CYCK 0.183 14605208 Q9VXL5 Q9VL58 Q9VXL5 Q9VL58 0.183 14605208 Q9VXL5 Q9VM98 Q9VXL5 CG11327-RA 0.183 14605208 Q9VXL5 Q9VTX2 Q9VXL5 SMYD4 0.183 14605208 Q9VXL5 Q9VXL5 Q9VXL5 Q9VXL5 0.21 14605208 Q9VZ27 Q9VXL5 CG18292-RA Q9VXL5 0.183 14605208 Q9VZ81 Q9VXL5 Q9VZ81 Q9VXL5 0.183 14605208 Q9W1A4 Q9VXL5 TAMO Q9VXL5 0.183 14605208 Q9W352 Q9VXL5 CFP1 Q9VXL5 0.183 14605208