PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG7849, IP08469p CG9934, isoform A, CG9934, isoform B, LD24832p 14605208 biogrid exp G G G G G G G G G Spinophilin, isoform J CG9934, isoform A, CG9934, isoform B, LD24832p 25294943 intact exp G G G G G G D CG9934, isoform A, CG9934, isoform B, LD24832p 14605208 intact exp G G G G G Mer CG9934, isoform A, CG9934, isoform B, LD24832p 15710747 biogrid,i2d exp G G G G G G G G G Glycogenin CG9934, isoform A, CG9934, isoform B, LD24832p 14605208 biogrid,i2d,mint,intact exp G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Uch CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G Hsc70Cb, isoform G, Hsc70Cb, isoform H CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G LD07294p, Two A-associated protein of 42kDa CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G Prosbeta6 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG1227, isoform A, CG1227, isoform B, LD17053p CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G eff CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG15602, isoform A, CG15602, isoform B, IP09819p, IP09919p CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Vps36 ortho G G G G G G G G G G Dodeca-satellite-binding protein 1, isoform A, Dodeca-satellite-binding protein 1, isoform B, Dodeca-satellite-binding protein 1, isoform D, Dodeca-satellite-binding protein 1, isoform E, Dodeca-satellite-binding protein 1, isoform F, Dodeca-satellite-binding protein 1, isoform G, Dodeca-satellite-binding protein 1, isoform H CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G Vha14-1 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G Npl4 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G EG:171D11.2 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G Ahcy13 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p SrpR-beta ortho G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Vacuolar protein sorting-associated protein 29 ortho G G G G G G G G G G Hrs CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG5625-RB ortho G G G G G G G G G G rad23 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG5203-PA, Carboxy terminus of Hsp70-interacting protein, RE01069p ortho G G G G G G G G G G dtpr2 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G GH01724p, p47 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G Itp-r83A CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG10640-PA, isoform A, LD28904p, Uev1A, isoform C ortho G G G G G G G G G G faf CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p vih ortho G G G G G G G G G G CG31251, RE67940p CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G TER94 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Spt6 ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G Ubiquitin-fold modifier 1 CG9934, isoform A, CG9934, isoform B, LD24832p ortho slmb CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Ufd1-like ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p ND-B8 ortho G CG9934, isoform A, CG9934, isoform B, LD24832p LD38919p, Ubiquilin, isoform A, Ubiquilin, isoform B ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG8209, GM09977p ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Ubiquitin thioesterase OTU1 ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG8549, isoform B, CG8549-PA ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p CG3000-PA, isoform A, GH07620p, RE20929p, Retina aberrant in pattern, isoform B ortho G G G G G G G G G G Dpit47-RA CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Mad2, RE72064p ortho G G CG9934, isoform A, CG9934, isoform B, LD24832p PCID2 ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p LD37736p, Zpr1 ortho G G G G G G G G G G Hsc70-5 CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G CG15261-PA, GM01181p, UK114, isoform B CG9934, isoform A, CG9934, isoform B, LD24832p ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VK44 Q9W2J6 - 14605208 - X 2 Q9VK44 Q24564 - 15710747 - X 2 Q9VK44 A1Z6K0 - 14605208 - X 2 Q9VK44 two hybrid 14605208 direct interaction X 2 Q9VK44 Q24564 two hybrid 15710747 direct interaction X 2 Q9VK44 two hybrid 14605208 direct interaction X 2 Q9VK44 two hybrid 14605208 physical association X 2 Q9VK44 Q24564 two hybrid 15710747 physical association X 2 Q9VK44 Q9W2J5 two hybrid 14605208 physical association X 2 Q9VK44 Q9W2J6 two hybrid 14605208 physical association X 2 Q9VK44 A1Z6K0 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Mer CG9934 MI:0018(two hybrid)|MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(biogrid) DIP_26359|BIOGRID_63137 -|bait -|prey CG9934 CG7849 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact) DIP_25693|UniProt_52938 -|prey -|bait CG9934 Glycogenin MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_47855|MINT_17776|UniProt_53396 prey|prey|prey bait|bait|bait CG9934 Glycogenin MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_26128 - - CG7849 CG9934 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_47526 bait prey Q9V9K5 CG9934 MI:0398(two hybrid pooling approach) 14605208 taxid:0() taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0471(mint) MINT_17345 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VK44 Q24564 Q9VK44 MER 0.033 15710747 Q9W2J6 Q9VK44 GLYCOGENIN Q9VK44 0.183 14605208 Q9VK44 M9NFI9 Q9VK44 M9NFI9 0.126 25294943