PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus D4, isoform A, Dd4 protein, LD29238p CG6506, LD38742p 14605208 intact exp G D4, isoform A, Dd4 protein, LD29238p BcDNA.LD34343 14605208 intact,dip exp G G G G G G G G G Bap170-RA D4, isoform A, Dd4 protein, LD29238p 18259215 intact exp G G G G G G G G D4, isoform A, Dd4 protein, LD29238p NimC1 14605208 intact exp G Dorsal interacting protein 3, RE40480p D4, isoform A, Dd4 protein, LD29238p 14605208 intact exp G G G G CG10654, isoform B D4, isoform A, Dd4 protein, LD29238p 14605208 intact exp G G SP555-RB D4, isoform A, Dd4 protein, LD29238p 16603075 intact exp Helix loop helix protein 4C, isoform B D4, isoform A, Dd4 protein, LD29238p 14605208 intact exp G CG8854-RB D4, isoform A, Dd4 protein, LD29238p 14605208 intact exp D4, isoform A, Dd4 protein, LD29238p CG34168-RA 14605208 intact exp G D4, isoform A, Dd4 protein, LD29238p CG11906, RE39769p 14605208 intact,dip exp G G G G G G G G D4, isoform A, Dd4 protein, LD29238p L(3)mbt interacting protein 1, isoform A, L(3)mbt interacting protein 1, isoform E, RE35228p 14605208 intact exp G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9W4I4 Q7K3G5 two hybrid 14605208 physical association X 2 Q7K3G5 Q7JZD5 two hybrid 14605208 physical association X 2 Q7K3G5 two hybrid 14605208 physical association X 2 Q9VJU5 Q7K3G5 two hybrid 14605208 physical association X 2 Q8SXZ6 Q7K3G5 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VTY7 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VZ22 two hybrid 14605208 physical association X 2 Q7K3G5 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VB23 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VX12 two hybrid 14605208 physical association X 2 Q9W4I4 Q7K3G5 two hybrid 14605208 physical association X 2 H1UUE3 Q7K3G5 two hybrid 14605208 physical association X 2 Q7K3G5 Q7JZD5 two hybrid 14605208 physical association X 2 Q0E8T4 Q7K3G5 two hybrid array 16603075 physical association X 2 Q9VJU5 Q7K3G5 two hybrid 14605208 physical association X 2 Q8SXZ6 Q7K3G5 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VTY7 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VZ22 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VJM1 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VB23 two hybrid 14605208 physical association X 2 Q7K3G5 Q9VX12 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B d4 CG1908 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_57122 bait prey d4 CG10654 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip) UniProt_59349|DIP_7278 bait|- prey|- d4 CG6506 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip) UniProt_25599|DIP_19887 bait|- prey|- d4 HLH4C MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_25596 bait prey d4 CG11906 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact) DIP_10399|UniProt_64413 -|bait -|prey d4 wdb MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact) DIP_19886|UniProt_25598 -|bait -|prey d4 CG8854-RB MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_25600 bait prey d4 CG34168-RA MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip) UniProt_25597|DIP_19885 bait|- prey|- d4 nimC1 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_25601 bait prey d4 CG8854 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_19888 - - d4 Dip3 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_51116 bait prey CG14042 d4 MI:0018(two hybrid) 16603075 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_44523 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q7K3G5 Q7JZD5 D4 DIP3 0.21 14605208 Q7K3G5 A1Z8V2 D4 A1Z8V2 0.033 14605208 Q7K3G5 Q0E8T4 D4 SP555-RB 0.126 16603075 Q9VB23 Q7K3G5 WDB D4 0.21 14605208 Q9VX12 Q7K3G5 Q9VX12 D4 0.21 14605208 Q9VZ22 Q7K3G5 LINT-1 D4 0.21 14605208 Q8SXZ6 Q7K3G5 Q8SXZ6 D4 0.21 14605208 Q9VJM1 Q7K3G5 CG34168-RA D4 0.183 14605208 Q9VJU5 Q7K3G5 NIMC1 D4 0.21 14605208 Q9VTY7 Q7K3G5 Q9VTY7 D4 0.21 14605208 Q9W4I4 Q7K3G5 HLH4C D4 0.21 14605208 Q7K3G5 A1Z6M0 D4 BAP170 0.21 18259215 Q7K3G5 H1UUE3 D4 CG8854-RB 0.183 14605208