PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Activity-regulated cytoskeleton associated protein 1, LD41905p Rae1 22036573 biogrid exp G G G G G G G G G G CG7049-PA Rae1 22036573 biogrid exp G G G G G G G G G G CG18789 Rae1 22036573 biogrid exp CG1532, isoform B, CG1532-PA Rae1 22036573 biogrid exp G G G G G G G G G G Hsf Rae1 22036573 biogrid exp G G G G G G G G G G sgg Rae1 25294943 intact exp G G G Alpha-Esterase-2, isoform A, Alpha-Esterase-2, isoform B, GH15053p Rae1 22036573 biogrid exp G G G Rae1 Treh 22036573 biogrid exp G G G G G G G G G G sob Rae1 22036573 biogrid exp G G CG18787 Rae1 22036573 biogrid exp Mannose-1-phosphate guanyltransferase beta Rae1 22036573 biogrid exp G G G G G G G G G G mtg Rae1 22036573 biogrid exp G anon1A4 Rae1 22036573 biogrid exp G G G G G G G G G G Arginine methyltransferase 8, RE49877p Rae1 22036573 biogrid exp G G G G G G Tal Rae1 22036573 biogrid exp G G G G G G G G G G CG14543, RE68515p Rae1 22036573 biogrid exp G G G G G G G G G G Dorsocross2, RE40937p Rae1 22036573 biogrid exp Ubc7 Rae1 22036573 biogrid exp G G G G G G G G G G Rae1 CG3726, isoform B 22036573 biogrid exp G G G G G G G G Farnesyl pyrophosphate synthase, GM06581p, RE52884p Rae1 22036573 biogrid exp G G G G G G G G G G zip Rae1 22036573 biogrid exp G G G G G G G G G G Transgelin Rae1 22036573 biogrid exp G G G G G G G G G G alphaTry Rae1 22036573 biogrid exp G G G CG31142, RE39515p Rae1 22036573 biogrid exp G G G G G G G G G G RpS21 Rae1 22036573 biogrid exp G G G G G G G G G G Arr1 Rae1 22036573 biogrid exp G G G G G Taf5 Rae1 22036573 biogrid exp, ortho G G G G G G G G Ebony activating protein, GH12334p Rae1 22036573 biogrid exp, ortho G G G G G G G G G Trx-2 Rae1 22036573 biogrid exp, ortho G G G G G G G G G G WD repeat-containing protein 82 Rae1 22036573 biogrid exp, ortho G G G G G G G G G G Swip-1 Rae1 22036573 biogrid exp, ortho G G G G G G G G G G Glutamate oxaloacetate transaminase 1, isoform B Rae1 22036573 biogrid exp, ortho G G G G G G G G G G CSN8 Rae1 ortho G G G G G G G G G G CG2862, isoform C, CG2862-PA, isoform A, RH02823p, RH49748p Rae1 ortho G G G G G G G G G G WD repeat-containing protein 59 homolog Rae1 ortho G G G G G G G G G CSN6 Rae1 ortho G G G G G G G G G G Dead box protein 80, isoform E Rae1 ortho G G G G G G G G G G Cdc37 Rae1 ortho G G G G G G G G G G MED4 Rae1 ortho G G G Fs(2)Ket Rae1 ortho G G G G G G G G G G BcDNA.LD18761, Nucleoporin 107kD Rae1 ortho G G G G G G G G G G Ufd1-like Rae1 ortho G G G G G G G G G G sbr Rae1 ortho G G G G G G G G G G LD23072p, Partner of drosha, isoform A, Partner of drosha, isoform C Rae1 ortho G G G G G mbo Rae1 ortho G G hpo Rae1 ortho G G G G G G G G G G nup44A Rae1 ortho G G G G G G G G G G Pen Rae1 ortho G G FI07923p, Karyopherin beta 3, isoform A, Karyopherin beta 3, isoform B Rae1 ortho G G G G G G G G G G Bx42 Rae1 ortho G G G G G G G G G G CG5705, LD18447p Rae1 ortho G G G G G GH01087p, Nucleoporin 93kD-2 Rae1 ortho G G G tsu Rae1 ortho G G G G G G G G G G Nup98-RA Rae1 ortho G G G G G G G G Glycoprotein 93, LD23641p Rae1 ortho G G G G G G G G G G Cullin 3, isoform F, FI19425p1 Rae1 ortho G G G G G G G G G G CycB Rae1 ortho G G G noi Rae1 ortho G G G G G G G G G G RpII215 Rae1 ortho G G G G G G G G G G lin19 Rae1 ortho G G G G G G G G G G Rae1 kdn ortho G G G G G G G G G G Caspar, isoform A, Caspar, isoform B, LD03368p Rae1 ortho G G G G G G G G G G CG16941, GH03554p Rae1 ortho G G Sod Rae1 ortho G G G G G G G G G G Ubi-p63E Rae1 ortho G G G G G G G G G G PKD Rae1 ortho G G G G G G G G 14-3-3epsilon Rae1 ortho G G G G G G G G G G CG12050-RB Rae1 ortho G G G G G G G G G Dihydropteridine reductase, Dihydropteridine reductase, isoform A, Dihydropteridine reductase, isoform B, RE58329p Rae1 ortho G G G G G G G G G hiw Rae1 ortho G G G G G Succinyl-CoA:3-ketoacid-coenzyme A transferase Rae1 ortho G G G G G G G G G RpIII128 Rae1 ortho G G G G G G G G G DNApol-alpha180 Rae1 ortho G Taf6 Rae1 ortho G G G G G G G G G G CG7339, isoform A, CG7339, isoform B, GM16372p Rae1 ortho G G CG9143, LD11580p Rae1 ortho G G G G G Hel25E Rae1 ortho G G G G G G G G G G mio Rae1 ortho G G G G G G G G G G pAbp Rae1 ortho G G G G G G G G G G dod Rae1 ortho G G G G Usp7 Rae1 ortho G G G G G G G G G G EG:152A3.1 Rae1 ortho G G G G G G G G G Bub3-RA Rae1 ortho G G G G G G G G G G DNApol-alpha50 Rae1 ortho G LD41216p, SMU1 ortholog, isoform A, SMU1 ortholog, isoform B, SMU1 ortholog, isoform C Rae1 ortho G G G G G G G Ate1 Rae1 ortho G G G G G G G G G G SMC3 Rae1 ortho G G RFeSP-RB Rae1 ortho G G G G G G G G G G GH11602p, Gcn5 ortholog Rae1 ortho G G G G G G G G G DNApol-alpha73 Rae1 ortho G CG4390, isoform B Rae1 ortho G G G G G G G G G G Sin-RA Rae1 ortho G G G G G G G G G G DNApol-alpha60 Rae1 ortho G WD repeat-containing protein 26 homolog Rae1 ortho G G G G G G G G G G Rae1 CG7609, isoform B ortho G G G G G G G G Nup54 Rae1 ortho G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9W2E7 Q9I7N2 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9W0U6 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VJ26 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q7K1U0 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 O76927-2 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VYR1 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 A1ZAA5 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VST2 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 O16043 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9I7N3 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q8SWW7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VZI1 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 P22813 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 P49846 affinity chromatography technology 22036573 physical association X 2 Q9VBI0 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q99323-2 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VLN1 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 A4UZR3 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q7KN61 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 E2QCZ9 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 D3DMZ9 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VXE8 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q9VQS7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 Q8SX32 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 P04814 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 M9NES0 Q9W2E7 affinity chromatography technology 22036573 physical association X 2 Q9W2E7 affinity chromatography technology 22036573 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Hsf Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73455 bait prey CG18789 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72013 prey bait CG1129 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_68381 prey bait Arc1 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_66415 bait prey CG7049 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_64408 prey bait CG3726 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72164 bait prey RpS21 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_66973 bait prey Got1 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_69412 bait prey Taf5 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73613 bait prey eap Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_68342 prey bait Fpps Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_68062 bait prey CG14543 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_74652 prey bait Wdr82 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65406 bait prey CG10641 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65539 bait prey CG31142 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72873 prey bait Rae1 crl MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71929 prey bait Rae1 regucalcin MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_67346 prey bait Rae1 sob MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72131 prey bait Rae1 Treh MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_67723 prey bait Rae1 CG1532 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_64626 prey bait Rae1 Doc2 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_69939 bait prey Arr1 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73227 bait prey mtg Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_67870 prey bait Trx-2 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71712 prey bait CG18787 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_64407 prey bait alphaTry Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73949 bait prey Df31 Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_70117 bait prey zip Rae1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_64639 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9W2E7 P18431 Q9W2E7 SGG 0.126 25294943