PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Nucleoporin 43kD Toys are us 14605208 biogrid,i2d,mint,intact exp G G G G G N Nucleoporin 43kD 25294943 intact exp G G G Nrg Nucleoporin 43kD 25294943 intact exp G G G G G G G G Nucleoporin 43kD Putative SERF-like protein 25294943 intact exp Spinophilin, isoform J Nucleoporin 43kD 25294943 intact exp G G G G G Nucleoporin 43kD Thrombospondin, isoform A, Thrombospondin, isoform F 25294943 intact exp Kdm4B Nucleoporin 43kD 25294943 intact exp G G Nucleoporin 43kD 4E-binding protein THOR, CG8846-PA, HL08053p, Thor, isoform B 25294943 intact exp G G G G G G G G Nucleoporin 43kD CG16812, LD36945p 25294943 intact exp G G G G G G G G Ten-m Nucleoporin 43kD 25294943 intact exp G G G G G G Fmr1 Nucleoporin 43kD 14605208 biogrid,i2d,mint,intact exp G G G G G G Tab2-RA Nucleoporin 43kD 23749869 biogrid exp G G G G G G 14-3-3epsilon Nucleoporin 43kD 20818332 intact exp, ortho G G G G G G G G LP09464p, Nucleoporin 133kD Nucleoporin 43kD ortho G G G G G G Dmn Nucleoporin 43kD ortho G G G G G G G G Nup98-RA Nucleoporin 43kD ortho G G G G G G G G CG8258, LD24495p Nucleoporin 43kD ortho G G G G G G G G Nucleoporin 43kD IP07706p, p53-related protein kinase ortholog ortho G G G G G G G nup44A Nucleoporin 43kD ortho G G G G G G G G Nucleoporin 75kD, Nup75 Nucleoporin 43kD ortho G G G G G G G G Khc Nucleoporin 43kD ortho G G G G G G G G Nucleoporin 43kD rab3-GAP ortho G G G G G G G G Nucleoporin 43kD Probable tRNA N6-adenosine threonylcarbamoyltransferase ortho G G G G G G G Nucleoporin 43kD pic ortho G G G G G G G G Nucleoporin 43kD Nup160 ortho sec13 Nucleoporin 43kD ortho G G G G G G G G Nucleoporin 37kD, isoform A, Nucleoporin 37kD, isoform B, SD22926p Nucleoporin 43kD ortho G G G G Nucleoporin 43kD tectonic ortho Ubi-p63E Nucleoporin 43kD ortho G G G G G G G G Fs(2)Ket Nucleoporin 43kD ortho G G G G G G G G T-cp1 Nucleoporin 43kD ortho G G G G G G G G BcDNA.LD18761, Nucleoporin 107kD Nucleoporin 43kD ortho G G G G G G G G Nucleoporin 43kD LD47396p, Tcp-1eta ortho G G G G G G G G Xpac Nucleoporin 43kD ortho G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VE85 Q9VG62 - 14605208 - X 2 Q9VE85 Q9NFU0-4 - 14605208 - X 2 Q9VE85 Q6NQZ7 affinity chromatography technology 23749869 physical association X 2 Q9VE85 Q9VG62 two hybrid 14605208 direct interaction X 2 Q9VE85 Q9NFU0-3 two hybrid 14605208 direct interaction X 2 Q9VE85 Q9VG62 two hybrid 14605208 physical association X 2 Q9VE85 Q9NFU0 two hybrid 14605208 physical association X 2 Q9VE85 anti tag coimmunoprecipitation 25294943 association C 14 Q9VE85 anti tag coimmunoprecipitation 25294943 association C 43 Q9VE85 Q9VG62 two hybrid 14605208 physical association X 2 Q9VE85 Q9NFU0 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Nup43 trus MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip)|MI:0471(mint) BIOGRID_46470|UniProt_62142|DIP_24255|MINT_15976 prey|prey|-|prey bait|bait|-|bait Fmr1 Nup43 MI:0029(cosedimentation through density gradient)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208,20818332 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(intact)|(biogrid) UniProt_45094|MINT_16520|DIP_24854|UniProt_62753|BIOGRID_33625 neutral component|bait|-|bait|bait neutral component|prey|-|prey|prey Tab2 Nup43 MI:0004(affinity chromatography technology) 23749869 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_76329 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VE85 O61307 NUP43 TEN-M 0.126 25294943 Q9XZ56 Q9VE85 THOR NUP43 0.126 25294943 Q9VM97 Q9VE85 TSP NUP43 0.236 25294943 Q9VE85 P07207 NUP43 N 0.236 25294943 Q9VE85 P20241 NUP43 NRG 0.236 25294943 Q9VE85 Q9NFU0 NUP43 FMR1 0.183 14605208 Q9VG62 Q9VE85 TRUS NUP43 0.183 14605208 Q9VEW2 Q9VE85 Q9VEW2 NUP43 0.126 25294943 Q9VK18 Q9VE85 Q9VK18 NUP43 0.126 25294943 Q9VE85 P92177 NUP43 14-3-3EPSILON 0.081 20818332 Q9VE85 M9NFI9 NUP43 M9NFI9 0.126 25294943 Q9VE85 A1Z995 NUP43 A1Z995 0.126 25294943