PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG4813, LD46938p, RE63826p sec10 15710747 biogrid,i2d,intact exp G G G G CG14932, isoform B CG4813, LD46938p, RE63826p 14605208 biogrid,i2d,mint,intact exp CG1635, LD44914p CG4813, LD46938p, RE63826p 22036573 biogrid exp G G G G AT29209p CG4813, LD46938p, RE63826p i2d exp CkIIalpha CG4813, LD46938p, RE63826p 22036573 biogrid exp G G G G Synd CG4813, LD46938p, RE63826p 22036573 biogrid exp G G G G Adaptor protein complex 2, mu subunit, isoform A, Adaptor protein complex 2, mu subunit, isoform B, Adaptor protein complex 2, mu subunit, isoform C, Clathrin-associated adaptor complex AP-2 medium chain, Clathrin-associated protein, SD05403p CG4813, LD46938p, RE63826p 14605208 biogrid,i2d,mint,intact exp G G G G CG4813, LD46938p, RE63826p CG14297, IP09476p 14605208 biogrid,i2d,mint,intact exp CkIIbeta CG4813, LD46938p, RE63826p 22036573 biogrid exp G G G G HIP-R CG4813, LD46938p, RE63826p 22036573 biogrid exp CTP:phosphocholine cytidylyltransferase 1, isoform A, CTP:phosphocholine cytidylyltransferase 1, isoform B, CTP:phosphocholine cytidylyltransferase 1, isoform C, CTP:phosphocholine cytidylyltransferase 1, isoform D, CTP:phosphocholine cytidylyltransferase 1, isoform E, CTP:phosphocholine cytidylyltransferase 1, isoform F, LD46058p CG4813, LD46938p, RE63826p 22036573 biogrid exp G G G G CG4813, LD46938p, RE63826p CG6089 14605208 biogrid,i2d,mint,intact exp G G G G CG4813, LD46938p, RE63826p CG3927 14605208 biogrid,i2d,mint,intact exp CG5044-RB CG4813, LD46938p, RE63826p 22036573 biogrid exp G G G G CG4813, LD46938p, RE63826p CG5568, LD47944p 22036573 biogrid exp G UbcD2 CG4813, LD46938p, RE63826p 14605208 biogrid,i2d,mint,intact exp, ortho G G G G CG4813, LD46938p, RE63826p CG13001-PA, RE69682p 14605208,22036573 biogrid,i2d,mint,intact exp, ortho G G G arm CG4813, LD46938p, RE63826p ortho G G G G CG7220-RB CG4813, LD46938p, RE63826p ortho G G G G CG4813, LD46938p, RE63826p Usp7 ortho G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VCV3 Q9VX94 - 14605208 - X 2 Q9VCV3 - 14605208 - X 2 Q9VCV3 Q9VKM8 - 14605208 - X 2 Q9VCV3 P52485 - 14605208 - X 2 Q9VCV3 O62530 - 14605208 - X 2 Q9VCV3 Q9W240 - 14605208 - X 2 Q9VCV3 Q9XTM1 - 15710747 - X 2 Q9VCV3 Q9VE30 - 14605208 - X 2 Q9VCV3 Q9VX94 two hybrid 14605208 direct interaction X 2 Q9VCV3 P52485 two hybrid 14605208 direct interaction X 2 Q9VCV3 O62530 two hybrid 14605208 direct interaction X 2 Q9VCV3 Q960K8 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q9VX94 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q9VDI1 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q9VRQ4 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q9VKM7 two hybrid 14605208 direct interaction X 2 Q9VCV3 Q9W240 two hybrid 14605208 direct interaction X 2 Q9VCV3 Q9VE30 two hybrid 14605208 direct interaction X 2 Q9VCV3 E1JHF9 two hybrid 14605208 direct interaction X 2 Q9VCV3 Q9XTM1 two hybrid 15710747 direct interaction X 2 Q9VCV3 C4NYP8 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q95TK5 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q7K4C7 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 P08182 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 A4V2B8 affinity chromatography technology 22036573 physical association X 2 Q9VCV3 Q9VX94 two hybrid 14605208 physical association X 2 Q9VCV3 two hybrid 14605208 physical association X 2 Q9VCV3 P52485 two hybrid 14605208 physical association X 2 Q9VCV3 O62530 two hybrid 14605208 physical association X 2 Q9VCV3 Q9VE30 two hybrid 14605208 physical association X 2 Q9VCV3 Q9VKM7 two hybrid 14605208 physical association X 2 Q9VCV3 Q9W240 two hybrid 14605208 physical association X 2 Q9VCV3 Q9XTM1 two hybrid 15710747 physical association X 2 Q9VCV3 Q9VX94 two hybrid 14605208 physical association X 2 Q9VCV3 P52485 two hybrid 14605208 physical association X 2 Q9VCV3 O62530 two hybrid 14605208 physical association X 2 Q9VCV3 Q9VE30 two hybrid 14605208 physical association X 2 Q9VCV3 Q9VKF4 two hybrid 14605208 physical association X 2 Q9VCV3 Q9W240 two hybrid 14605208 physical association X 2 Q9VCV3 Q9VKM7 two hybrid 14605208 physical association X 2 Q9VCV3 Q9XTM1 two hybrid fragment pooling approach 15710747 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG5044 CG4813 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65112 bait prey CkIIalpha CG4813 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_74355 bait prey CkIIbeta CG4813 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73782 bait prey CG4813 CG6089 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_13956|UniProt_49319 bait|bait prey|prey CG4813 CG14932 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_15516|MINT_7858|BIOGRID_31783|UniProt_48814 -|prey|prey|prey -|bait|bait|bait CG1635 CG4813 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_66813 prey bait Cct1 CG4813 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_68808 prey bait CG4813 CG14297 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0471(mint)|MI:0465(dip) BIOGRID_31532|UniProt_47714|MINT_29308|DIP_14400 prey|bait|bait|- bait|prey|prey|- CG4813 Synd MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_68771 bait prey CG4813 CG3927 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0465(dip) BIOGRID_45366|MINT_14572|UniProt_49987|DIP_22780 prey|bait|bait|- bait|prey|prey|- CG4813 CG13001 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 14605208,22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|(biogrid)|(biogrid) MINT_27127|UniProt_51427|BIOGRID_67711|BIOGRID_38360 prey|prey|prey|prey bait|bait|bait|bait CG4813 HIP MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65768 prey bait CG4813 sec10 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact) DIP_27555|BIOGRID_62974|UniProt_42531 -|prey|prey -|bait|bait UbcD2 CG4813 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_61590|DIP_23716|BIOGRID_33335|MINT_15472 prey|-|prey|prey bait|-|bait|bait AP-50 CG4813 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|(intact)|(biogrid)|MI:0471(mint) DIP_23717|UniProt_61591|BIOGRID_33336|MINT_15473 -|prey|prey|prey -|bait|bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VCV3 O62530 Q9VCV3 AP-2MU 0.183 14605208 Q9XTM1 Q9VCV3 SEC10 Q9VCV3 0.155 15710747 Q9VCV3 P52485 Q9VCV3 UBCD2 0.21 14605208 Q9VKF4 Q9VCV3 Q9VKF4 Q9VCV3 0.183 14605208 Q9VX94 Q9VCV3 Q9VX94 Q9VCV3 0.183 14605208 Q9VE30 Q9VCV3 Q9VE30 Q9VCV3 0.183 14605208 Q9VKM7 Q9VCV3 CG6089 Q9VCV3 0.183 14605208 Q9W240 Q9VCV3 Q9W240 Q9VCV3 0.183 14605208