PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Roc2-RA Cullin 5, FI20194p1 15331761,18698375 biogrid exp, ortho G G G G G G G G G G gus Cullin 5, FI20194p1 20123973 intact exp, ortho G G G G G G G G G G Cullin 5, FI20194p1 DCN1-like protein 14605208 biogrid,i2d,mint,intact exp, ortho G G G G G G G G G G RpL19 Cullin 5, FI20194p1 ortho G G G G G G G G G G Trap1-RA Cullin 5, FI20194p1 ortho G G G G G G G G G G ILK Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 CSN6 ortho G G G G G G G G G G Cullin 5, FI20194p1 Ddx1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Ubc12 ortho G G G G G G G G G G Cullin 5, FI20194p1 60S ribosomal protein L27 ortho G G G G G G G G G G RpS19b Cullin 5, FI20194p1 ortho G RE62581p, RH06526p, Ribosomal protein L21, isoform A, Ribosomal protein L21, isoform B, Ribosomal protein L21, isoform C Cullin 5, FI20194p1 ortho G G G G G G G G G G Receptor protein serine/threonine kinase Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RpL5 ortho G G G G G G G G G G Ef1alpha100E Cullin 5, FI20194p1 ortho G G G G G G Cullin 5, FI20194p1 CTPsyn ortho G G G G G G G G G RpS25 Cullin 5, FI20194p1 ortho Cullin 5, FI20194p1 CG9485, isoform B ortho G G G G G G G G G LP09631p, Waterproof Cullin 5, FI20194p1 ortho G G G G G G U2af50 Cullin 5, FI20194p1 ortho G G G G G G G G G G Hsp83 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Aats-gly-RB ortho G G G G G G G G G G EG:BACR7A4.17 Cullin 5, FI20194p1 ortho G G G G G G G G G Cbp80 Cullin 5, FI20194p1 ortho G G G G G G G G G Cullin 5, FI20194p1 Nap1-RA ortho G G G G G G G G G G Cullin 5, FI20194p1 CG6287-PA, GH03305p ortho G G G G G G G G G G Cullin 5, FI20194p1 Rpb4 ortho ImpL3 Cullin 5, FI20194p1 ortho G G G G G G RpLP0 Cullin 5, FI20194p1 ortho G G G G G G G G G G Eno Cullin 5, FI20194p1 ortho G G G G G G G G G G sbr Cullin 5, FI20194p1 ortho G G G G G G G G G G SmD3 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 pic ortho G G G G G G G G G G CG10077, isoform D, CG10077-PA, isoform A, GH10652p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RpS10a ortho G RpS6 Cullin 5, FI20194p1 ortho G SdhA Cullin 5, FI20194p1 ortho G G G G G G G G G G Ubi-p63E Cullin 5, FI20194p1 ortho G G G G G G G G G G Rho-related BTB domain containing, isoform B Cullin 5, FI20194p1 ortho G G G G G G G G G G mts Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS5a Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 CSN1b ortho G G G G G G G G G G Cullin 2, isoform A, Cullin 2, isoform B, LD36177p Cullin 5, FI20194p1 ortho G G G G G G G G G G SkpA Cullin 5, FI20194p1 ortho G G G G G G G G G G Fem-1 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS4 Cullin 5, FI20194p1 ortho G G G G G G G G G G AnxB9 Cullin 5, FI20194p1 ortho G G G G G G G G G G Hsc70Cb, isoform G, Hsc70Cb, isoform H Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS20 Cullin 5, FI20194p1 ortho G G G G G G G G G G ade3 Cullin 5, FI20194p1 ortho G G G G G G Cullin 5, FI20194p1 RpL38 ortho G G G G G G G G G G TER94 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpL27A Cullin 5, FI20194p1 ortho G G G G G G G G G G AGO1-RC Cullin 5, FI20194p1 ortho G G G G G G G G G CG1416, isoform A, CG1416, isoform B, CG1416, isoform C, LD43819p Cullin 5, FI20194p1 ortho G G G G G G G G G G Skp2, isoform A, Skp2, isoform E Cullin 5, FI20194p1 ortho G G G G Cullin 5, FI20194p1 Roc1a ortho G G G G G G G G G Hsc70-3 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 bel ortho G G G G G G G G G G Bgb Cullin 5, FI20194p1 ortho G G G G G Cullin 5, FI20194p1 Art4 ortho G G G G G G Top2 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 40S ribosomal protein S24 ortho RPB3 Cullin 5, FI20194p1 ortho G G G G G G G G G G Aos1, CG12276 protein, CG12276-PA, LD33652p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Cullin 5, FI20194p1 ortho G G G G G G G G G G CG2937-PA, RE59650p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 mahj ortho G G G G G G G G G mle Cullin 5, FI20194p1 ortho G G G G G G G Cullin 5, FI20194p1 hlc ortho G G G G G G G G G Elongation factor Tu Cullin 5, FI20194p1 ortho G G G G G G G G G G Slh Cullin 5, FI20194p1 ortho G G G G G G G G G G Apoptosis-linked gene-2 Cullin 5, FI20194p1 ortho pAbp Cullin 5, FI20194p1 ortho G G G G G G G G G G Drep4 Cullin 5, FI20194p1 ortho G G G G G G G G G Chc Cullin 5, FI20194p1 ortho G G G G G G G G G G PCNA Cullin 5, FI20194p1 ortho G G G snf Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 l(2)35Bd ortho G G G G G G G G G Cullin 5, FI20194p1 GH06740p, Leucine-rich repeat 47, isoform A, Leucine-rich repeat 47, isoform B ortho G G Dhx15 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS13 Cullin 5, FI20194p1 ortho G G G G G G G G G G CG31759, isoform C, CG31759, isoform D Cullin 5, FI20194p1 ortho G G G Cullin 5, FI20194p1 RpL18 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Glycoprotein 93, LD23641p ortho G G G G G G G G G G CG34314-RA Cullin 5, FI20194p1 ortho Cullin 5, FI20194p1 Interleukin enhancer-binding factor 2 homolog ortho G G G G G G G G G G RpL8 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Upf1 ortho G G G G G G G G G G RpL4 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpII140 Cullin 5, FI20194p1 ortho G G G G G G G G G G Hsc70-5 Cullin 5, FI20194p1 ortho G G G G G G G G G G mtSSB Cullin 5, FI20194p1 ortho G G G G G G G G G RpL7 Cullin 5, FI20194p1 ortho G G G G G G G G G G ari-2 Cullin 5, FI20194p1 ortho G G G G G G G G G G Calcium-binding protein 1, isoform A, Calcium-binding protein 1, isoform B, LD28038p Cullin 5, FI20194p1 ortho G G G G G G G G G G Pcd Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RpL10Ab ortho G G G G G G G G G G CSN8 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RpS16 ortho G G G G G G G G G G AnxB10 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 CG12081, isoform A, CG12081, isoform B, LD20420p ortho G G G G G G G G G G Cullin 5, FI20194p1 AT20211p, CG10516 ortho G G G G G G G G G G IGF-II mRNA-binding protein, isoform L, IGF-II mRNA-binding protein, isoform M Cullin 5, FI20194p1 ortho G G G G G G G G G PyK Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RE28824p, Ribosomal protein L12, isoform A, Ribosomal protein L12, isoform B, Ribosomal protein L12, isoform C ortho G G G G G G G G G G Cullin 5, FI20194p1 RpL13A ortho G G G G G G G G G G CG6459 protein, CG6459-PA, LD29590p, P32 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpL15 Cullin 5, FI20194p1 ortho G G G G G G G G G G betaTub60D Cullin 5, FI20194p1 ortho G G G G G G G RpII215 Cullin 5, FI20194p1 ortho G G G G G G G G G G CG10924, isoform A, RE12569p Cullin 5, FI20194p1 ortho G G G CathD, Cathepsin D, SD07085p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 tRNA-splicing ligase RtcB homolog ortho G G G G G G G G G G Cullin 5, FI20194p1 CSN5 ortho G G G G G G G G G G CSN7 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Mcm7 ortho G RE54550p, Rab40, isoform B Cullin 5, FI20194p1 ortho G G G G G G G G G Cullin 5, FI20194p1 RpS28b ortho G G G G G G G G G G RpL11 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RpL35-RB ortho G G G G G G G G G G isoQC Cullin 5, FI20194p1 ortho G G G G G G G G G lin19 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS7 Cullin 5, FI20194p1 ortho G G G G G G G G G G betaTub56D Cullin 5, FI20194p1 ortho G G G G G G G G G G RpL22 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 AnxB11 ortho G G G G G G G G G G Cullin 5, FI20194p1 l(3)72Ab ortho G G G G G G G G G G Ef1beta Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 CG10343-PA, GM16226p ortho G G G G G G G G G G Cullin 5, FI20194p1 SmG ortho G G G G G G G G G G Cullin 5, FI20194p1 Nedd8 ortho G G G G G G G G G G CSN4 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS2 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 KLHL18, isoform A, KLHL18, isoform C, LD42169p ortho G G G G G G G G G G GM12291p, RE71510p, Translocon-associated protein delta, isoform A, Translocon-associated protein delta, isoform B Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Dis3, isoform A, Dis3, isoform B ortho Cullin 5, FI20194p1 CG2656, LD11854p ortho G G G G G G G G G G Elongin C, isoform A, Elongin C, isoform B, RE05591p, RH71704p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 RpL24 ortho G G G G G G G G G G Cullin 3, isoform F, FI19425p1 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 CG5913 ortho G G G G G G G G G G heph Cullin 5, FI20194p1 ortho G G G G G G G Cullin 5, FI20194p1 Nuclear receptor-binding protein homolog ortho G G G G G G G G G G Irbp Cullin 5, FI20194p1 ortho G G G EF2 Cullin 5, FI20194p1 ortho G G G G G G G G G G CSN3 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpII15 Cullin 5, FI20194p1 ortho G G G G G G G G G G alpha-Man-I Cullin 5, FI20194p1 ortho G scu Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Sce ortho G G G G G G G Uba3 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 AIF ortho G G G G G G G G G G RpS8 Cullin 5, FI20194p1 ortho G G G G G G G G G G l(2)tid Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 SmD2 ortho G G G G G G G G G G blw Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Peroxiredoxin 3, SD08737p, Thioredoxin peroxidase 3 ortho G G G G G G G G G G Cullin 5, FI20194p1 GDP dissociation inhibitor, isoform A, GDP dissociation inhibitor, isoform B, GDP dissociation inhibitor, isoform C, LD46767p, LP03430p ortho G G G G G G G G G G Cullin 5, FI20194p1 Cand1 ortho G G G G G G G G G G RpL3 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 SmD1 ortho G G G G G G G G G G Cullin 5, FI20194p1 AT07979p2, Lemming B, isoform A, Lemming B, isoform B, Lemming B, isoform C, Lemming B, isoform D ortho Cullin 5, FI20194p1 T-complex protein 1 subunit delta ortho G G G G G G G G G G RpS3 Cullin 5, FI20194p1 ortho Cullin 5, FI20194p1 CG14614-RA ortho G G G G G G G G G Defective in cullin neddylation protein Cullin 5, FI20194p1 ortho G G G G G G G G G G AT18160p, CG9945, isoform A, CG9945, isoform B Cullin 5, FI20194p1 ortho G G G G G Rox8-RD Cullin 5, FI20194p1 ortho G G G G G G G G G G Pabp2 Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 Nsun2 ortho G G G nemy Cullin 5, FI20194p1 ortho G G G G G G G G Cullin 5, FI20194p1 Vps36 ortho G G G G G G G G G G Aspartyl-tRNA synthetase, isoform A, Aspartyl-tRNA synthetase, isoform B, Aspartyl-tRNA synthetase, isoform C, GM14334p Cullin 5, FI20194p1 ortho G G G G G G G G G G Pre-mRNA-processing factor 39 Cullin 5, FI20194p1 ortho G G G G G G G G G G RpS9 Cullin 5, FI20194p1 ortho G G G G G G G G G G RE08669p, Ribosomal protein L6, isoform B Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 5, FI20194p1 CG7477 ortho G G G G G G G G Cullin 5, FI20194p1 eEF1delta ortho G G G G G G G G G G Cullin 5, FI20194p1 CG4849, LD28793p ortho G G G G G G G G G G His4, His4r, His4:CG31611, His4:CG33869, His4:CG33871, His4:CG33873, His4:CG33875, His4:CG33877, His4:CG33879, His4:CG33881, His4:CG33883, His4:CG33885, His4:CG33887, His4:CG33889, His4:CG33891, His4:CG33893, His4:CG33895, His4:CG33897, His4:CG33899, His4:CG33901, His4:CG33903, His4:CG33905, His4:CG33907, His4:CG33909 Cullin 5, FI20194p1 ortho Hsc70-1 Cullin 5, FI20194p1 ortho G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Cul-5 gus MI:0006(anti bait coimmunoprecipitation) 20123973 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_44732 prey bait Roc2 Cul-5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15331761,18698375 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_77116|BIOGRID_61817 bait|bait prey|prey Cul-5 CG7427 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0465(dip) UniProt_47226|MINT_28856|BIOGRID_31413|DIP_13909 prey|prey|bait|- bait|bait|prey|-

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VUQ8 Q9VAQ0 Q9VUQ8 CUL5 0.21 14605208 Q9VAQ0 A1Z6E0 CUL5 GUS 0.21 20123973