PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus LD13864p, MIP07457p, Not3, isoform A, Not3, isoform B gw 21981923 intact exp G G G G G G G G G G AGO1-RC gw 23172285,16815998,19797087,22117217,21646546 biogrid,intact,dip exp G G G G G G G G G LD39302p, Twin, isoform C gw 21981923 intact exp G G G G G G G G G G gw Pop2, isoform E 21981923 intact exp G G G G G G G G G G gw Rga 23172285,21981923 biogrid,intact exp G G G G G G G G G G PAB-dependent poly(A)-specific ribonuclease subunit PAN2 gw 21981923 biogrid,intact exp G G G G G G G G G G gw PAB-dependent poly(A)-specific ribonuclease subunit PAN3 23172285,21981923 biogrid exp G G G G G G G G G G pAbp gw 23172285,21063388,19797087,22117217 biogrid,mint,intact exp G G G G G G G G G G CG11486-RC gw 21981923 intact exp P-element somatic inhibitor, isoform C gw 22036573 biogrid exp G G G G G G G G ZAP3, isoform E gw 22036573 biogrid exp G G G G G G G G G G Not1 gw 23172285,21981923 biogrid,intact exp G G G G G G G G G Tao gw 14605208 biogrid,i2d,intact exp G G G G G G G G G 14-3-3epsilon gw 20818332 intact exp G G G G G G G G G G gw LD18634p, Nervous fingers 1, Zinc-finger transcription factor nerfin-1 19797087 biogrid exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8IQW6 Q8SY33 - 14605208 - X 2 Q0KHQ5 Q8SY33 two hybrid 14605208 physical association X 2 Q32KD4 Q8SY33 anti tag coimmunoprecipitation 21646546 physical association X 2 Q8SY33 anti tag coimmunoprecipitation 21981923 association C 3 Q0KHQ5 Q8SY33 two hybrid 14605208 physical association X 2 Q94547 Q8SY33 anti tag coimmunoprecipitation 21981923 physical association X 2 E1JHY7 Q8SY33 anti tag coimmunoprecipitation 21981923 physical association X 2 Q8SY33 A8DY81 anti bait coimmunoprecipitation 21981923 physical association X 2 Q8SY33 A8DY81 anti tag coimmunoprecipitation 21981923 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 anti tag coimmunoprecipitation 21063388 physical association X 2 P21187 Q8SY33 pull down 21063388 direct interaction X 2 D3DMN9 Q8SY33 anti tag coimmunoprecipitation 21981923 physical association X 2 Q8SY33 anti tag coimmunoprecipitation 22117217 association C 3 Q7K126 Q8SY33 anti tag coimmunoprecipitation 21981923 physical association X 2 Q32KD4 Q8SY33 anti tag coimmunoprecipitation 16815998 physical association X 2 Q32KD4 Q8SY33 pull down 16815998 physical association X 2 Q32KD4 Q8SY33 confocal microscopy 16815998 colocalization X 2 Q8IMX1 Q8SY33 anti tag coimmunoprecipitation 21981923 physical association X 2 A1Z7K9 Q8SY33 anti tag coimmunoprecipitation 21981923 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B gw ZAP3 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65268 bait prey gw Q9VWG8 MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_29183 prey bait gw CG8232 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0914(association)|MI:0915(physical association) (intact)|(intact) UniProt_45206|UniProt_45208 bait|bait prey|prey gw Psi MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72688 prey bait pAbp gw MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19797087,21063388,22117217 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid) UniProt_46708|UniProt_45169|UniProt_45170|UniProt_45172|UniProt_45163|BIOGRID_61837|UniProt_45171|UniProt_45162|UniProt_111537|UniProt_45174|UniProt_45173|UniProt_45176|UniProt_45175|UniProt_111531|UniProt_111532|UniProt_111530|UniProt_111535|UniProt_111536|UniProt_111533|UniProt_111534|UniProt_111523|UniProt_111524|BIOGRID_75337|BIOGRID_75338 prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|bait bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|prey Tao gw MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_47582|BIOGRID_31498 bait|bait prey|prey twin gw MI:0029(cosedimentation through density gradient)|MI:0007(anti tag coimmunoprecipitation) 20818332,21981923 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact) UniProt_45094|UniProt_45211 neutral component|prey neutral component|bait AGO1 gw MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 16815998 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact) UniProt_43272|UniProt_43273|UniProt_43274 prey|prey|neutral component bait|bait|neutral component gw CG11486-RC MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0914(association)|MI:0915(physical association) (intact)|(intact) UniProt_45206|UniProt_45209 bait|bait prey|prey l(2)NC136 gw MI:0007(anti tag coimmunoprecipitation)|MI:0029(cosedimentation through density gradient) 20818332,21981923 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact) UniProt_45207|UniProt_45094 prey|neutral component bait|neutral component gw nerfin-1 MI:0004(affinity chromatography technology) 19797087 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_61835 bait prey Rga gw MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45213 prey bait gw Pop2 MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45212 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8SY33 Q0KHQ5 GW TAO 0.332 14605208 Q8SY33 A5YKK6 GW CNOT1 0.21 21984184 Q8SY33 Q32KD4 GW AGO1 0.454 16815998 Q8SY33 Q7KY08 GW AGO1 0.21 22117217 Q9UFF9 Q8SY33 CNOT8 GW 0.21 21984184 Q94547 Q8SY33 RGA GW 0.376 21981923,23172285 Q95RR8 Q8SY33 Q95RR8 GW 0.376 21981923,23172285 Q8SY33 P21187 GW PABP 0.867 23172285,19797087,22117217,21063388 Q8SY33 P92177 GW 14-3-3EPSILON 0.081 20818332