PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus mts Lst8 22036573 biogrid exp G G G G G G G G G unk Lst8 22068330 intact exp G G G G G G G G GH28857p, Spatzle-Processing enzyme Lst8 22036573 biogrid exp G G G G Cyp6a13 Lst8 22036573 biogrid exp G G G G G G G G AT22779p Lst8 i2d exp Syp Lst8 22036573 biogrid exp G G G G G G G G rictor-RA Lst8 22068330 intact exp G G G G G G G G G Fer1HCH-RD Lst8 22036573 biogrid exp G G G G G G G G G CG2720-PA, LD03220p Lst8 22068330 intact exp G G G G G G G G G igloo-L Lst8 22036573 biogrid exp G G G ND75 Lst8 22036573 biogrid exp G G G G G G G G G Sec23 Lst8 22068330 intact exp G G G G G G G G G CG7206-RB Lst8 22036573 biogrid exp G G G G G G G G G Lst8 Nervous wreck, isoform I 22036573 biogrid exp G G G G l(1)G0022 Lst8 22068330 intact exp G G G G G G G G G LD07294p, Two A-associated protein of 42kDa Lst8 22036573 biogrid exp G G G G G G G G G Lst8 4E-binding protein THOR, CG8846-PA, HL08053p, Thor, isoform B 22068330 intact exp G G G G G G G G G Lst8 MRG15 22036573 biogrid exp G G G G G G G G G CG4407-PA, isoform A, LD26737p Lst8 22036573 biogrid exp G G G G G G G G G CG9173 Lst8 14605208 biogrid,mint,intact exp Atg4a Lst8 22036573 biogrid exp G G G G G G G G G PSR Lst8 22036573 biogrid exp G G G G G G G G G CG8654-RA Lst8 22036573 biogrid exp G G G G G CG11504-RA Lst8 22036573 biogrid exp G G G G G G CTP:phosphocholine cytidylyltransferase 2, GH25855p Lst8 22036573 biogrid exp G G G L Lst8 22068330 intact exp G G G G G G G G G CG10566, isoform A, CG10566, isoform B, GH23156p Lst8 22036573 biogrid exp G G G sec24 Lst8 22068330 intact exp G G G G G G G G G RpL10 Lst8 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G HMG coenzyme A synthase, isoform A, HMG coenzyme A synthase, isoform B, HMG coenzyme A synthase, isoform C, HMG coenzyme A synthase, isoform D, HMG coenzyme A synthase, isoform E, HMG coenzyme A synthase, isoform F, HMG coenzyme asynthase, LD26976p Lst8 22036573 biogrid exp G G G G G G G G G CG8888, GH26015p Lst8 22036573 biogrid exp G G G RpS3A Lst8 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G Probable ribosome production factor 1 Lst8 22036573 biogrid exp G G G G G G G G G CG3344, GH21114p Lst8 22036573 biogrid exp G l(3)01239 Lst8 22068330 intact exp G G G G G G G G G LD47396p, Tcp-1eta Lst8 22068330 intact exp, ortho G G G G G G G G G Vha55 Lst8 22036573 biogrid exp, ortho G G G G G G G G G Sin1 Lst8 22068330 intact exp, ortho G G G G G Lst8 Lst8 14605208 intact exp, ortho G G G G G G G G G Tor Lst8 22068330 intact exp, ortho G G G G G G G G G Lst8 Raptor, isoform B, Raptor, isoform C 22068330 intact exp, ortho Spt5 Lst8 ortho G G G G G G G G G Nuclear migration protein NudC, NudC, isoform A, NudC, isoform B, RE55422p Lst8 ortho G G G G G G G G G CG5482, isoform A, CG5482, isoform B, CG5482, isoform C, CG5482, isoform D, LD36412p Lst8 ortho G G G G G G G G G CG9149 Lst8 ortho G G G G G G G G G Pgk Lst8 ortho G G G G G G G G G Pglym87 Lst8 ortho Su(z)12 Lst8 ortho G G G G G G G G G Cyp1 Lst8 ortho G G G G G G G G G Hsp60 Lst8 ortho G G G G G G G G G RpS9 Lst8 ortho G G G G G G G G G sbr Lst8 ortho G G G G G G G G G CG18815-RA Lst8 ortho G G G G G G G G G Arginine methyltransferase 1, CG6554 protein, CG6554-PA, LD28808p Lst8 ortho G G G G G G G G G Probable prefoldin subunit 5 Lst8 ortho G G G G G G G G G FK506-bp2 Lst8 ortho G G G G G G G G G Klp61F Lst8 ortho G Gigas, isoform A Lst8 ortho G G G G G G G G G sec13 Lst8 ortho G G G G G G G G G emb Lst8 ortho G G G G G G G G G FI11917p, KEAP1, Keap1, isoform B Lst8 ortho G G G G G G G G Lst8 CG7033, SD02216p ortho G G G G G G G G G Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55 Lst8 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9W328 - 14605208 - X 2 M9PIM0 Q9W328 - 14605208 - X 2 Q9W328 - 14605208 - X 2 Q9VYI5 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q7K3N4 Q9W328 affinity chromatography technology 22036573 physical association X 2 M9NFB4 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9VKB4 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9VP78 Q9W328 affinity chromatography technology 22036573 physical association X 2 E1JIJ5 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q7K4Q9 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q7K4R2 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9Y0I1 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q8I0T0 Q9W328 affinity chromatography technology 22036573 physical association X 2 A4V449 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9W0D9 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9VJZ5 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9V4U9 Q9W328 affinity chromatography technology 22036573 physical association X 2 P23696 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q95T29 Q9W328 affinity chromatography technology 22036573 physical association X 2 P55830-2 Q9W328 two hybrid 14605208 direct interaction X 2 M9PIM0 Q9W328 two hybrid 14605208 direct interaction X 2 Q9VPW2 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9W0F5 Q9W328 two hybrid 14605208 direct interaction X 2 Q9VSU9 Q9W328 affinity chromatography technology 22036573 physical association X 2 Q9VD28 Q9W328 affinity chromatography technology 22036573 physical association X 2 P55830 Q9W328 two hybrid 14605208 physical association X 2 M9PIM0 Q9W328 two hybrid 14605208 physical association X 2 Q9W0F5 Q9W328 two hybrid 14605208 physical association X 2 Q9W328 two hybrid 14605208 physical association X 2 Q9W328 anti tag coimmunoprecipitation 22068330 association C 9 Q9W328 anti tag coimmunoprecipitation 22068330 association C 10 Q9W328 anti tag coimmunoprecipitation 22068330 association C 13 Q9W328 anti tag coimmunoprecipitation 22068330 association C 9 Q9W328 anti tag coimmunoprecipitation 22068330 association C 6 Q9W328 anti tag coimmunoprecipitation 22068330 association C 8 Q9W328 anti tag coimmunoprecipitation 22068330 association C 5 Q9W328 anti tag coimmunoprecipitation 22068330 association C 5 Q9W328 anti tag coimmunoprecipitation 22068330 association C 5 Q9W328 anti tag coimmunoprecipitation 22068330 association C 4 Q9W328 anti tag coimmunoprecipitation 22068330 association C 11 Q9W328 anti tag coimmunoprecipitation 22068330 association C 9 Q9W328 anti tag coimmunoprecipitation 22068330 association C 14 P55830 Q9W328 two hybrid 14605208 physical association X 2 M9PIM0 Q9W328 two hybrid 14605208 physical association X 2 Q9W0F5 Q9W328 two hybrid 14605208 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9W328 P23696 LST8 MTS 0.126 22036573 Q9XZ56 Q9W328 THOR LST8 0.126 22068330 Q9Y0I1 Q9W328 MRG15 LST8 0.126 22036573 Q9W328 Q86B79 LST8 UNK 0.126 22068330 Q9W328 P55830 LST8 RPS3A 0.332 14605208 Q9W328 Q94511 LST8 ND75 0.126 22036573 Q9W328 P31409 LST8 VHA55 0.126 22036573 Q9W328 Q9V719 LST8 SIN1 0.126 22068330 Q9W328 Q9VK45 LST8 TOR 0.236 22068330 Q9W328 Q9VWJ6 LST8 RICTOR 0.126 22068330 Q9W328 A1Z813 LST8 SEC24AB 0.126 22068330 Q9W328 O61231 LST8 RPL10 0.332 14605208 Q9W328 Q7JXA2 LST8 L 0.126 22068330 Q9W328 Q9V4U9 LST8 CYP6A13 0.126 22036573 Q9W328 Q9VD28 LST8 PSR 0.126 22036573 Q9W328 Q9VHL2 LST8 TCP-1ETA 0.126 22068330 Q9W328 Q9VKB4 LST8 Q9VKB4 0.126 22036573 Q9W328 Q9VNF8 LST8 SEC23 0.126 22068330 Q9W328 Q9VPN5 LST8 HOP 0.126 22068330 Q9W328 Q9VTE5 LST8 L(3)01239 0.126 22068330 Q9W328 Q9VXQ5 LST8 TCP-1ZETA 0.126 22068330 Q9W328 Q9W0F5 LST8 Q9W0F5 0.183 14605208 Q9W437 Q9W328 RAPTOR LST8 0.236 22068330