PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus C52A11.4d cat-4 21110867 intact exp G F19C7.8a cat-4 23549480 intact exp G cat-4 UPF0046 protein T07D4.2 14704431 biogrid,i2d,mint,intact,dip exp C26C6.8 cat-4 23549480 intact exp cat-4 F48E3.4 19123269 intact exp cat-4 Y20F4.3a 23549480 intact exp F40F8.8b cat-4 14704431 biogrid,i2d,mint,intact,dip exp G cat-4 T22D1.12a 14704431 biogrid,i2d,mint,intact,dip exp G F45E4.3e cat-4 21110867 intact exp G fut8 cat-4 23549480 intact exp cat-4 F54D10.7 19123269 intact exp cat-4 cat-4 11731503 intact exp, ortho G rbf-1 cat-4 ortho G C24A11.9 cat-4 ortho G cat-2 cat-4 ortho F25D1.1a cat-4 ortho G cat-4 F28B3.8 ortho G kin-10 cat-4 ortho G Y38C1AA.13 cat-4 ortho Putative folylpolyglutamate synthase cat-4 ortho G cat-4 C47E12.5a ortho G cat-4 C53D5.6 ortho G Uncharacterized F-box/LRR-repeat protein C02F5.7 cat-4 ortho G kin-1 cat-4 ortho G cat-4 4D561 ortho G cat-4 homt-1 ortho G cat-4 T10B5.5a ortho G Oxysterol-binding protein cat-4 ortho G hsp-1 cat-4 ortho G Uncharacterized protein C30C11.4 cat-4 ortho G cdc-37 cat-4 ortho G kin-3 cat-4 ortho G cat-4 Y105E8B.3 ortho G cat-4 C01G10.8 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q19980 Q9GZG8 - 14704431 - X 2 Q20232 Q19980 - 14704431 - X 2 Q19980 - 14704431 - X 2 Q19980 Q22306 two hybrid 14704431 direct interaction X 2 Q19980 Q9GZG8 two hybrid 14704431 direct interaction X 2 Q20232 Q19980 two hybrid 14704431 direct interaction X 2 Q19980 Q22306 affinity chromatography technology 14704431 physical association X 2 Q19980 Q22306 two hybrid 14704431 physical association X 2 Q19980 Q9GZG8 two hybrid 14704431 physical association X 2 Q20232 Q19980 two hybrid 14704431 physical association X 2 Q19980 Q22306 anti tag coimmunoprecipitation 14704431 physical association X 2 Q19980 Q22306 two hybrid pooling approach 14704431 physical association X 2 Q19980 Q9GZG8 two hybrid pooling approach 14704431 physical association X 2 Q19980 Q9TZ84 two hybrid pooling approach 19123269 physical association X 2 Q19980 Q9TZ84 two hybrid array 19123269 physical association X 2 Q20232 Q19980 two hybrid pooling approach 14704431 physical association X 2 G5ECZ8 Q19980 two hybrid pooling approach 21110867 physical association X 2 Q19980 Q19980 two hybrid 11731503 physical association X 2 Q19980 H2KYL0 anti tag coimmunoprecipitation 21110867 physical association X 2 Q19980 H2KYL0 two hybrid pooling approach 21110867 physical association X 2 Q19980 G5EFE7 two hybrid 23549480 physical association X 2 Q19980 Q18204 two hybrid 23549480 physical association X 2 Q19980 Q8MQ71 two hybrid 23549480 physical association X 2 Q19980 Q95XA9 two hybrid 23549480 physical association X 2 Q9GPA1 Q19980 two hybrid pooling approach 19123269 physical association X 2 Q9GPA1 Q19980 two hybrid array 19123269 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B cat-4 arrd-6 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact)|MI:0471(mint) BIOGRID_22678|DIP_2301|UniProt_30685|MINT_628 prey|-|prey|prey bait|-|bait|bait cat-4 F48E3.4 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20762|UniProt_18852 prey|prey bait|bait cat-4 F45E4.3 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 21110867 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_22439|UniProt_21957 prey|prey bait|bait cat-4 F54D10.7 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20763|UniProt_18851 prey|prey bait|bait cat-4 fut-8 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24090 prey bait cat-4 gap-3 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24336 prey bait cat-4 mpz-1 MI:0398(two hybrid pooling approach) 21110867 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_21899 prey bait cat-4 npr-12 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint)|MI:0465(dip) UniProt_28147|BIOGRID_24249|MINT_2243|DIP_3757 prey|prey|prey|- bait|bait|bait|- cat-4 T07D4.2 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0465(dip) BIOGRID_23990|UniProt_27883|MINT_1977|MINT_6430|UniProt_993|DIP_3496 prey|prey|prey|prey|prey|- bait|bait|bait|bait|bait|- cat-4 CELE_F19C7.8 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24133 prey bait C26C6.8 cat-4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24104 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q19980 Q19980 CAT-4 CAT-4 0.332 11731503 Q19980 Q18204 CAT-4 Q18204 0.183 23549480 Q19980 G5ECZ8 CAT-4 MPZ-1 0.126 21110867 Q8MQ71 Q19980 Q8MQ71 CAT-4 0.183 23549480 Q9GPA1 Q19980 Q9GPA1 CAT-4 0.236 19123269 Q19980 H2KYL0 CAT-4 TAG-80 0.236 21110867 Q20232 Q19980 ARRD-6 CAT-4 0.155 14704431 Q9GZG8 Q19980 NPR-12 CAT-4 0.155 14704431 Q9TZ84 Q19980 Q9TZ84 CAT-4 0.236 19123269 Q95XA9 Q19980 GAP-3 CAT-4 0.183 23549480 Q19980 G5EFE7 CAT-4 FUT-8 0.183 23549480 Q22306 Q19980 Q22306 CAT-4 0.416 14704431