PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Inhibitor of apoptosis homolog, T27F2.3 sel-11 14704431 biogrid,intact exp G mett-10 sel-11 14704431 biogrid,i2d,mint,intact exp G cks-1 sel-11 14704431 biogrid,i2d,mint,intact,dip exp G sel-11 Y119C1B.8a 14704431 biogrid,i2d,mint,intact,dip exp G Non-specific protein-tyrosine kinase sel-11 23549480 intact exp G sel-11 K08D10.7 14704431 biogrid,i2d,mint,intact,dip exp rpn-11 sel-11 11559592,14704431 biogrid,i2d,mint,intact exp G pas-6 sel-11 ortho G pas-7 sel-11 ortho G sel-11 tom-1 ortho G sel-11 pas-5 ortho G pas-1 sel-11 ortho G F45D3.5, SEL-1 sel-11 ortho G sel-11 H06H21.6 ortho G sel-11 T22D1.9 ortho G sel-11 Y105E8A.2 ortho G sel-11 Y56A3A.2 ortho G sel-11 der-2 ortho G NADPH--cytochrome P450 reductase sel-11 ortho G sel-11 cup-2 ortho hrdl-1 sel-11 ortho G C42C1.15 sel-11 ortho sel-11 Ubiquitin carboxyl-terminal hydrolase ortho G sel-11 usp-7 ortho G pbs-4 sel-11 ortho G ire-1 sel-11 ortho G C34F6.7 sel-11 ortho 3-hydroxy-3-methylglutaryl coenzyme A reductase, HMG-CoA reductase sel-11 ortho G let-70 sel-11 ortho G sel-11 sgk-1 ortho sel-11 aph-2 ortho G sel-11 pbs-3 ortho G atx-3 sel-11 ortho pbs-6 sel-11 ortho G apl-1 sel-11 ortho G sel-11 pas-4 ortho G R12E2.3 sel-11 ortho G sel-11 pas-2 ortho G sel-11 sel-11 ortho G Ancient ubiquitous protein 1 homolog sel-11 ortho G D1022.1a sel-11 ortho G rer-1 sel-11 ortho G sel-11 Y55D5A.3 ortho sel-11 T06D8.9 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q20798 - 14704431 - X 2 Q17868 Q20798 - 14704431 - X 2 Q20798 O76577 - 11559592 - X 2 Q20798 O76577 - 12679813 - X 2 Q20798 G5EFA2 - 14704431 - X 2 Q20798 Q21319 - 14704431 - X 2 Q20798 Q09357 - 14704431 - X 2 Q20798 Q95Y80 two hybrid 14704431 direct interaction X 2 Q17868 Q20798 two hybrid 14704431 direct interaction X 2 Q20798 O76577 two hybrid 14704431 direct interaction X 2 Q20798 Q21319 two hybrid 14704431 direct interaction X 2 Q20798 G5EFA2 two hybrid 14704431 direct interaction X 2 Q20798 Q09357 two hybrid 14704431 direct interaction X 2 Q20798 Q95Y80 two hybrid 14704431 physical association X 2 Q17868 Q20798 two hybrid 14704431 physical association X 2 Q20798 Q21319 two hybrid 14704431 physical association X 2 Q20798 G5EFA2 two hybrid 14704431 physical association X 2 Q20798 Q09357 two hybrid 14704431 physical association X 2 Q20798 Q95Y80 two hybrid pooling approach 14704431 physical association X 2 G5EE56 Q20798 two hybrid 23549480 physical association X 2 Q17868 Q20798 two hybrid pooling approach 14704431 physical association X 2 Q20798 O76577 two hybrid pooling approach 11559592 physical association X 2 Q20798 Q21319 two hybrid pooling approach 14704431 physical association X 2 Q20798 G5EFA2 two hybrid pooling approach 14704431 physical association X 2 Q20798 Q09357 two hybrid pooling approach 14704431 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B sel-11 src-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23920 prey bait sel-11 scrm-8 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_31186|MINT_1234|DIP_2798 prey|prey|- bait|bait|- sel-11 bet-1 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip)|MI:0471(mint) UniProt_28700|DIP_4309|MINT_2822 prey|-|prey bait|-|bait sel-11 Q22837 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint) DIP_3843|MINT_2339 -|prey -|bait rpn-11 sel-11 MI:0398(two hybrid pooling approach)|MI:0397(two hybrid array)|MI:0018(two hybrid) 11559592,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|(biogrid) MINT_1200|UniProt_642|BIOGRID_23239 bait|bait|bait prey|prey|prey cks-1 sel-11 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0465(dip)|(intact)|(biogrid) MINT_6847|DIP_1303|UniProt_29685|BIOGRID_21524 bait|-|bait|bait prey|-|prey|prey mett-10 sel-11 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_29260|DIP_4867|BIOGRID_25396|MINT_3431 bait|-|bait|bait prey|-|prey|prey sel-11 bir-1 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_24351|UniProt_28232 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q20798 Q09357 SEL-11 METT-10 0.309 14704431 Q21319 Q20798 SCRM-8 SEL-11 0.155 14704431 Q20798 G5EFA2 SEL-11 BIR-1 0.126 14704431 Q22837 Q20798 Q22837 SEL-11 0.033 14704431 Q20798 G5EE56 SEL-11 SRC-1 0.183 23549480 Q20798 O76577 SEL-11 RPN-11 0.286 14704431,11559592 Q20798 Q17868 SEL-11 CKS-1 0.309 14704431 Q95Y80 Q20798 BET-1 SEL-11 0.309 14704431