PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Y45F10D.13a M02A10.3a, Sli-1 protein 10615043,23549480,19447967 biogrid,mint,intact exp G M02A10.3a, Sli-1 protein F07D10.1 14704431 biogrid,i2d,mint,intact,dip exp G M02A10.3a, Sli-1 protein T23F6.4a 14704431 biogrid,i2d,mint,intact,dip exp M02A10.3a, Sli-1 protein Y105E8B.5 14704431 biogrid,i2d,mint,intact,dip exp G pal-1 M02A10.3a, Sli-1 protein 14704431 biogrid,i2d,mint,intact exp lec-1 M02A10.3a, Sli-1 protein 14704431 biogrid,i2d,mint,intact,dip exp G M02A10.3a, Sli-1 protein F23C8.4 14704431 biogrid,i2d,mint,intact,dip exp G M02A10.3a, Sli-1 protein ftt-2 14704431 biogrid,mint,intact,dip exp G vit-6 M02A10.3a, Sli-1 protein 14704431 i2d,mint,intact exp C31C9.2 M02A10.3a, Sli-1 protein 14704431 biogrid,i2d,mint,intact,dip exp G atg-7 M02A10.3a, Sli-1 protein 14704431 biogrid,intact exp G M02A10.3a, Sli-1 protein Y65B4BR.4a 19123269 intact exp G rpl-7 M02A10.3a, Sli-1 protein 14704431 biogrid,i2d,mint,intact,dip exp G Non-specific protein-tyrosine kinase M02A10.3a, Sli-1 protein 23549480 intact exp G sem-5 M02A10.3a, Sli-1 protein 10615043,14704431 biogrid,i2d,mint,intact exp, ortho G let-23 M02A10.3a, Sli-1 protein 7652556 dip exp, ortho G M02A10.3a, Sli-1 protein Y116A8C.36a ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P18948-2 Q19019 - 14704431 - X 2 Q19019 P29355 - 10615043 - X 2 Q19019 P29355 - 12679813 - X 2 Q19019 G5EBK4 - 14704431 - X 2 Q19019 O01802 - 14704431 - X 2 Q19019 P34766 - 14704431 - X 2 Q19019 Q9TXH9 - 14704431 - X 2 Q19019 Q9XU67 - 14704431 - X 2 Q19019 Q9NF11 - 12679813 - X 2 Q19019 Q9NF11 - 14704431 - X 2 Q19019 - 10615043 - X 2 Q19019 - 12679813 - X 2 Q19019 O17626 - 14704431 - X 2 Q19019 Q19162 - 14704431 - X 2 Q19019 - 14704431 - X 2 Q19019 P36573 - 14704431 - X 2 Q19019 - 14704431 - X 2 P18948-2 Q19019 two hybrid 14704431 physical association X 2 Q19019 P24348 biochemical 7652556 physical association X 2 Q19019 P34766 two hybrid 14704431 physical association X 2 Q19019 Q9TXH9 two hybrid 14704431 physical association X 2 Q19019 Q20655 two hybrid 14704431 physical association X 2 Q19019 O01802 two hybrid 14704431 physical association X 2 Q19019 G5EBK4 two hybrid 14704431 physical association X 2 Q19019 Q9XU67 two hybrid 14704431 physical association X 2 Q19019 O17626 two hybrid 14704431 physical association X 2 Q19019 Q19162 two hybrid 14704431 physical association X 2 Q19019 two hybrid 14704431 physical association X 2 Q19019 P36573 two hybrid 14704431 physical association X 2 Q19019 Q9NF11 two hybrid 14704431 physical association X 2 Q19019 P29355 two hybrid pooling approach 10615043 physical association X 2 Q19019 O62482 two hybrid pooling approach 10615043 physical association X 2 Q19019 P34766 two hybrid pooling approach 14704431 physical association X 2 Q19019 Q9TXH9 two hybrid pooling approach 14704431 physical association X 2 Q19019 O01802 two hybrid pooling approach 14704431 physical association X 2 Q19019 P18948 two hybrid pooling approach 14704431 physical association X 2 Q19019 G5EBK4 two hybrid pooling approach 14704431 physical association X 2 Q19019 Q9XU67 two hybrid pooling approach 14704431 physical association X 2 Q19019 Q9N2Z7 two hybrid pooling approach 19123269 physical association X 2 Q19019 Q9N2Z7 two hybrid array 19123269 physical association X 2 Q19019 O62482 two hybrid pooling approach 19447967 physical association X 2 Q19019 O62482 two hybrid pooling approach 19447967 physical association X 2 Q19019 O62482 two hybrid 19447967 physical association X 2 Q19019 O62482 two hybrid pooling approach 19447967 physical association X 2 Q19019 O45539 two hybrid 23549480 physical association X 2 Q19019 O17626 two hybrid pooling approach 14704431 physical association X 2 Q19019 Q19162 two hybrid pooling approach 14704431 physical association X 2 Q19019 Q95ZT1 two hybrid pooling approach 14704431 physical association X 2 Q19019 O45904 two hybrid pooling approach 14704431 physical association X 2 Q19019 Q9NF11 two hybrid pooling approach 14704431 physical association X 2 Q19019 G5EC32 two hybrid 23549480 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B sli-1 Q21591 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0465(dip) MINT_1403|DIP_2958 bait|- prey|- rpl-7 sli-1 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0471(mint)|MI:0465(dip) BIOGRID_23431|UniProt_31341|MINT_1400|DIP_2955 prey|prey|prey|- bait|bait|bait|- sli-1 atg-7 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_23433|UniProt_31344 bait|bait prey|prey sli-1 sorb-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24401 prey bait sli-1 Q9U3E3 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_31343|MINT_1401 bait|bait prey|prey sli-1 Y105E8B.5 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_2961|MINT_1406|BIOGRID_23436|UniProt_31347 -|bait|bait|bait -|prey|prey|prey lec-1 sli-1 MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|MI:0465(dip) BIOGRID_23435|DIP_2960 prey|- bait|- sli-1 CG3634 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_23426 bait prey sli-1 rbd-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_31346|MINT_1404|DIP_2959 bait|bait|- prey|prey|- sli-1 ftt-2 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0465(dip) DIP_2954 - - sli-1 ubxn-1 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|MI:0465(dip) MINT_1398|UniProt_31340|BIOGRID_23429|DIP_2953 bait|bait|bait|- prey|prey|prey|- sli-1 wwp-1 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_19292|UniProt_21202 bait|bait prey|prey vit-6 sli-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_31345|MINT_1402|DIP_2957 prey|prey|- bait|bait|- src-2 sli-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24196 bait prey C31C9.2 sli-1 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(intact) DIP_2950|MINT_1395|UniProt_31337 -|prey|prey -|bait|bait pal-1 sli-1 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0465(dip)|(biogrid)|(intact) MINT_1396|DIP_2951|BIOGRID_23427|UniProt_31339 prey|-|prey|prey bait|-|bait|bait sli-1 beta4GalNAcTB MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_23432 bait prey sli-1 RpS10a MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_23434 bait prey let-23 sli-1 MI:0401(biochemical) 7652556 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0465(dip) DIP_986 - - sli-1 ftt-2 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_1399|UniProt_31342 bait|bait prey|prey lec-1 sli-1 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_1405|UniProt_31348 prey|prey bait|bait sli-1 rpl-11.2 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0465(dip)|(intact) MINT_1397|BIOGRID_23428|DIP_2952|UniProt_31338 bait|bait|-|bait prey|prey|-|prey sorb-1 sli-1 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 10615043,19447967 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|MI:0471(mint) UniProt_1158|UniProt_23049|3354|UniProt_22658|BIOGRID_29503|UniProt_22862|UniProt_22936|MINT_1407 prey|bait|prey|bait|bait|bait|bait|prey bait|prey|bait|prey|prey|prey|prey|bait sem-5 sli-1 MI:0398(two hybrid pooling approach)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 10615043,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|MI:0471(mint)|(intact) MINT_6397|UniProt_1064|BIOGRID_21577|MINT_6902|3072 prey|bait|bait|bait|bait bait|prey|prey|prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q21591 Q19019 Q21591 SLI-1 0.033 14704431 Q19019 P29355 SLI-1 SEM-5 0.126 10615043 Q19019 G5EC32 SLI-1 SORB-1 0.183 23549480 Q19019 P24348 SLI-1 LET-23 0.033 7652556 Q19019 O45539 SLI-1 SRC-2 0.183 23549480 Q9NF11 Q19019 Q9NF11 SLI-1 0.155 14704431 Q20655 Q19019 FTT-2 SLI-1 0.033 14704431 Q19019 O45904 SLI-1 LEC-1 0.126 14704431 Q9N2Z7 Q19019 WWP-1 SLI-1 0.236 19123269 Q9TXH9 Q19019 UBXN-1 SLI-1 0.155 14704431 Q9XU67 Q19019 RBD-1 SLI-1 0.155 14704431 Q19019 O62482 SLI-1 SORB-1 0.554 19447967,10615043 Q19162 Q19019 RPL-11.2 SLI-1 0.155 14704431 Q19019 O17626 SLI-1 O17626 0.155 14704431 Q95ZT1 Q19019 FTT-2 SLI-1 0.126 14704431 Q19019 P36573 SLI-1 LEC-1 0.033 14704431 Q9U3E3 Q19019 Q9U3E3 SLI-1 0.033 14704431 Q19019 P34766 SLI-1 PAL-1 0.126 14704431 Q19019 P18948 SLI-1 VIT-6 0.126 14704431 Q19019 G5EBK4 SLI-1 ATG-7 0.126 14704431 Q19019 O01802 SLI-1 RPL-7 0.155 14704431