PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus mel-26 ubc-9 23918937 intact exp G ubc-9 ubc-9 11731503,14711411,14704431 biogrid,i2d,intact exp G W04D2.1a ubc-9 14704431 biogrid,i2d,mint,intact,dip exp G tbx-2 ubc-9 23595631 biogrid exp G ubc-9 Y57A10A.8 19123269 intact exp G ubc-9 Y59A8B.6 i2d exp G snpc-1.4 ubc-9 19123269 intact exp arl-13 ubc-9 23128241 biogrid exp G ubc-9 sop-2 15107848 biogrid exp G gei-17 ubc-9 19123269 intact exp G smo-1 ubc-9 11731503,14711411,14704431,19123269 biogrid,i2d,intact exp G ran-2 ubc-9 18692475,unassigned701 biogrid,mint,intact exp G brd-1 ubc-9 14711411,14704431 biogrid,i2d,intact exp C45G3.5 ubc-9 19123269 intact exp G ubc-9 Y43C5A.6a 11731503,14711411,11778048 mint,intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P55853 Q95017 - 14711411 - X 2 P55853 Q95017 - 11731503 - X 2 Q95017 - 11731503 - X 2 Q23158 Q95017 - 14704431 - X 2 Q95017 Q95017 - 14711411 - X 2 Q95017 G5EGG8 - 11731503 - X 2 Q95017 G5EGG8 - 11778048 - X 2 Q95017 G5EGG8 - 12679813 - X 2 Q95017 G5EGG8 - 14711411 - X 2 Q95017 - 14711411 - X 2 P55853 Q95017 two hybrid 14704431 direct interaction X 2 P34342 Q95017 two hybrid 18692475 direct interaction X 2 Q965H3 Q95017 two hybrid 15107848 direct interaction X 2 Q965H3 Q95017 enzymatic study 15107848 direct interaction X 2 Q95017 Q19691 two hybrid 23595631 direct interaction X 2 Q95017 Q95017 two hybrid 14704431 direct interaction X 2 Q95017 Q9XVU8 two hybrid 14704431 direct interaction X 2 Q95017 Q21209 two hybrid 14704431 direct interaction X 2 Q23158 Q95017 two hybrid 14704431 physical association X 2 Q94420 Q95017 two hybrid fragment pooling approach 23918937 physical association X 2 P55853 Q95017 two hybrid 11731503 physical association X 2 P55853 Q95017 two hybrid 14711411 physical association X 2 P55853 Q95017 two hybrid 14711411 physical association X 2 P55853 Q95017 two hybrid pooling approach 19123269 physical association X 2 P55853 Q95017 two hybrid array 19123269 physical association X 2 P34342 Q95017 two hybrid - physical association X 2 G5EF84 Q95017 two hybrid pooling approach 19123269 physical association X 2 G5EF84 Q95017 two hybrid array 19123269 physical association X 2 Q23158 Q95017 two hybrid pooling approach 14704431 physical association X 2 Q95Q25 Q95017 two hybrid 11731503 physical association X 2 Q95Q25 Q95017 two hybrid pooling approach 11778048 physical association X 2 Q95Q25 Q95017 two hybrid 14711411 physical association X 2 Q95Q25 Q95017 two hybrid 14711411 physical association X 2 Q95017 Q95017 two hybrid 11731503 physical association X 2 Q95017 Q95017 two hybrid 14711411 physical association X 2 Q95017 Q9NA84 two hybrid pooling approach 19123269 physical association X 2 Q95017 Q9NA84 two hybrid array 19123269 physical association X 2 Q95017 Q21209 two hybrid 14711411 physical association X 2 Q95017 Q21209 anti tag coimmunoprecipitation 14711411 physical association X 2 Q95017 Q21209 two hybrid 14711411 physical association X 2 Q95017 Q21209 two hybrid 14711411 physical association X 2 Q95017 Q21747 two hybrid pooling approach 19123269 physical association X 2 Q95017 Q94361 two hybrid pooling approach 19123269 physical association X 2 Q95017 Q21747 two hybrid array 19123269 physical association X 2 Q95017 Q94361 two hybrid array 19123269 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ran-2 ubc-9 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(biogrid)|(intact) MINT_4247|BIOGRID_28990|UniProt_25240 null|bait|null prey|prey|prey atn-1 ubc-9 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_28329|MINT_2449|DIP_3940 bait|bait|- prey|prey|- brd-1 ubc-9 MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down) 14704431,14711411 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_308|UniProt_324|UniProt_311|BIOGRID_26366|UniProt_320 bait|prey|prey|prey|bait prey|bait|bait|bait|prey ubc-9 gip-2 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18433|UniProt_20346 prey|prey bait|bait ubc-9 rad-51 MI:0096(pull down)|MI:0398(two hybrid pooling approach)|MI:0096(pull down)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 11731503,11778048,14711411 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|MI:0471(mint)|(intact) UniProt_317|113937|UniProt_318|UniProt_1441|MINT_3029|UniProt_840 bait|prey|prey|prey|prey|prey prey|bait|bait|bait|bait|bait btbd-10 ubc-9 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20729|UniProt_18817 bait|bait prey|prey mel-26 ubc-9 MI:0018(two hybrid) 23918937 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23275 bait prey smo-1 ubc-9 MI:0398(two hybrid pooling approach)|MI:0096(pull down)|MI:0398(two hybrid pooling approach)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 11731503,14704431,14711411,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_18816|UniProt_310|UniProt_20728|UniProt_312|UniProt_842|BIOGRID_26365 prey|prey|prey|bait|bait|prey bait|bait|bait|prey|prey|bait ubc-9 sop-2 MI:0018(two hybrid)|MI:0018(two hybrid) 15107848 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_28580|BIOGRID_28576 bait|prey prey|bait ubc-9 Y57A10A.8 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20731|UniProt_18819 prey|prey bait|bait gei-17 ubc-9 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18818|UniProt_20732 bait|bait prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q95017 Q19691 UBC-9 TBX-2 0.309 23595631 Q9NA84 Q95017 Q9NA84 UBC-9 0.236 19123269 Q95017 Q94361 UBC-9 GEI-17 0.236 19123269 Q95017 G5EF84 UBC-9 GIP-2 0.236 19123269 Q95017 H2L0N8 UBC-9 ARL-13 0.523 23128241 Q95017 Q21747 UBC-9 BTBD-10 0.236 19123269 Q95017 Q95017 UBC-9 UBC-9 0.648 11731503,14711411,14704431 Q95017 Q94420 UBC-9 MEL-26 0.21 23918937 Q95017 P34342 UBC-9 RAN-2 0.454 unassigned701,18692475 Q95017 Q23158 UBC-9 ATN-1 0.155 14704431 Q965H3 Q95017 SOP-2 UBC-9 0.523 15107848 Q95Q25 Q95017 RAD-51 UBC-9 0.712 11778048,11731503,14711411 Q95017 Q21209 UBC-9 BRD-1 0.692 14704431,14711411 Q95017 P55853 UBC-9 SMO-1 0.794 19123269,14704431,11731503,14711411