PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus wts-1 yap-1 23396260 biogrid exp wts-1 F45E1.7b 23549480 intact exp wts-1 C47D12.2 14704431 biogrid,i2d,mint,intact,dip exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q18668 O45797 - 14704431 - X 2 O45797 affinity chromatography technology 23396260 physical association X 2 Q18668 O45797 two hybrid 14704431 direct interaction X 2 Q18668 O45797 two hybrid 14704431 physical association X 2 Q18668 O45797 two hybrid pooling approach 14704431 physical association X 2 Q09989 O45797 two hybrid 23549480 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B wts-1 sdpn-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23629 prey bait wts-1 C47D12.2 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip)|MI:0471(mint) BIOGRID_21903|UniProt_29997|DIP_1614|MINT_7217 prey|prey|-|prey bait|bait|-|bait