PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus C01G6.4 nhr-41 14704431 i2d,mint,intact,dip exp T17H7.4d C01G6.4 14704431 biogrid,intact,dip exp G C01G6.4 Y104H12A.1a 14704431 biogrid exp ers-1 C01G6.4 ortho G C01G6.4 Y65B4BR.4a ortho G Ancient ubiquitous protein 1 homolog C01G6.4 ortho G R12E2.3 C01G6.4 ortho G F39B2.2 C01G6.4 ortho G F40G9.17 C01G6.4 ortho ubq-2 C01G6.4 ortho G C01G6.4 rpn-7 ortho G C01G6.4 C07A12.7a ortho G rpn-3 C01G6.4 ortho G C01G6.4 Y54G2A.31 ortho G kin-10 C01G6.4 ortho G apl-1 C01G6.4 ortho G C01G6.4 F10G7.8 ortho G Y92H12A.2a C01G6.4 ortho G B0205.3 C01G6.4 ortho G usp-14 C01G6.4 ortho G rpn-11 C01G6.4 ortho G C01G6.4 C18F10.7a ortho G C01G6.4 C07G1.5 ortho G C01G6.4 T06D8.8 ortho G C01G6.4 rpn-12 ortho G F15C11.2a C01G6.4 ortho G R02D3.3a C01G6.4 ortho G C01G6.4 rpn-6.1 ortho G dpy-23 C01G6.4 ortho G C01G6.4 T22D1.9 ortho G C01G6.4 F02E8.3 ortho G alx-1 C01G6.4 ortho G C01G6.4 C01G6.4 ortho G C01G6.4 usp-7 ortho G C01G6.4 Y39A1A.5 ortho G kin-3 C01G6.4 ortho G let-70 C01G6.4 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q17573 H2KYY3 - 14704431 - X 2 Q17573 - 14704431 - X 2 Q17573 H2KYY9 two hybrid 14704431 direct interaction X 2 Q17573 two hybrid 14704431 direct interaction X 2 Q17573 Q9N4B8 two hybrid 14704431 physical association X 2 Q17573 Q95QA6 two hybrid 14704431 physical association X 2 Q17573 H2KYY5 two hybrid pooling approach 14704431 physical association X 2 Q17573 Q9N4B8 two hybrid pooling approach 14704431 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B C01G6.4 pat-12 MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_28016 prey bait C01G6.4 Q22534 MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_2112 prey bait C01G6.4 pat-12 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_24122 prey bait C01G6.4 nhr-41 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip)|MI:0471(mint) UniProt_29518|DIP_1133|MINT_6660 bait|-|bait prey|-|prey C01G6.4 pat-12 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0465(dip) DIP_3629 - -