PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus csn-4 Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp Y54G11A.10a Y62E10A.16 unassigned1274 intact exp F15C11.2a Y62E10A.16 14704431 biogrid exp Pyruvate kinase Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp unc-62 Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp C27B7.4 Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp his-4, his-8, his-20, his-22, his-52, his-54 Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp F02E9.1 Y62E10A.16 19123269 intact exp F15C11.2 Y62E10A.16 14704431 mint,intact,dip exp F01G10.2 Y62E10A.16 19123269 intact exp F41C6.6 Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp F07A11.2a Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp F22H10.3 Y62E10A.16 14704431 biogrid,i2d,mint,intact,dip exp Y62E10A.16 Y62E10A.16 19123269,14704431 biogrid,i2d,mint,intact,dip exp, ortho ZK829.7 Y62E10A.16 ortho unc-6 Y62E10A.16 ortho Y62E10A.16 Y54G11A.2 ortho Protein SHQ1 homolog Y62E10A.16 ortho mre-11 Y62E10A.16 ortho tag-172 Y62E10A.16 ortho tag-165 Y62E10A.16 ortho D2063.3a Y62E10A.16 ortho Metallophosphoesterase 1 homolog Y62E10A.16 ortho cul-3 Y62E10A.16 ortho mys-1 Y62E10A.16 ortho haly-1 Y62E10A.16 ortho Y37D8A.9b Y62E10A.16 ortho byn-1 Y62E10A.16 ortho C09G12.9 Y62E10A.16 ortho smo-1 Y62E10A.16 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9U1W5 Q9U1W5 - 14704431 - X 2 Q9U1W5 Q18241 - 14704431 - X 2 Q9U1W5 - 14704431 - X 2 Q9U1W5 Q20271 - 14704431 - X 2 Q9U1W5 O17836 - 14704431 - X 2 Q9U1W5 Q95QM8 - 14704431 - X 2 Q9U1W5 G5EFF7 - 14704431 - X 2 Q9U1W5 Q9N5D6 - 14704431 - X 2 Q9U1W5 Q9N359 - 14704431 - X 2 Q9U1W5 Q94188 - 14704431 - X 2 Q9U1W5 Q18241 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q95QM8 two hybrid 14704431 direct interaction X 2 Q9U1W5 G5EFF7 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q20271 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q27894 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q9U1W5 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q9N359 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q94188 two hybrid 14704431 direct interaction X 2 Q9U1W5 B7WNA0 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q9N5D6-3 two hybrid 14704431 direct interaction X 2 Q9U1W5 Q18241 two hybrid 14704431 physical association X 2 Q9U1W5 Q19130 two hybrid 14704431 physical association X 2 Q9U1W5 G5EFF7 two hybrid 14704431 physical association X 2 Q9U1W5 O17836 two hybrid 14704431 physical association X 2 Q9U1W5 Q20271 two hybrid 14704431 physical association X 2 Q9U1W5 Q27894 two hybrid 14704431 physical association X 2 Q9U1W5 Q9N5D6 two hybrid 14704431 physical association X 2 Q9U1W5 Q9N359 two hybrid 14704431 physical association X 2 Q9U1W5 Q94188 two hybrid 14704431 physical association X 2 Q9U1W5 Q9U1W5 two hybrid 14704431 physical association Y 1 Q9U1W5 Q18241 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q19130 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 O17835 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q20271 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q27894 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q9N5D6 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q9U1W5 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q9U1W5 two hybrid pooling approach 19123269 physical association X 2 Q9U1W5 Q9U1W5 two hybrid array 19123269 physical association X 2 Q9U1W5 Q9N359 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 O18672 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 Q94188 two hybrid pooling approach 14704431 physical association X 2 Q9U1W5 O17761 two hybrid pooling approach 19123269 physical association X 2 Q9U1W5 O01314 two hybrid pooling approach 19123269 physical association X 2 Q9U1W5 O17761 two hybrid array 19123269 physical association X 2 Q9U1W5 O01314 two hybrid array 19123269 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9U1W5 O17836 GCL-1 PYK-1 0.033 14704431 Q9U1W5 O17835 GCL-1 PYK-1 0.126 14704431 Q9U1W5 O17761 GCL-1 ECH-8 0.236 19123269 Q9U1W5 O01314 GCL-1 O01314 0.236 19123269 Q9U1W5 Q94188 GCL-1 Q94188 0.155 14704431 Q9U1W5 Q18241 GCL-1 RAD-26 0.155 14704431 Q9U1W5 Q19130 GCL-1 Q19130 0.155 14704431 Q9U1W5 Q9U1W5 GCL-1 GCL-1 0.436 19123269,14704431 Q9U1W5 A5PEX5 GCL-1 A5PEX5 0.183 26780296 Q9U1W5 O18672 GCL-1 O18672 0.155 14704431 Q9U1W5 Q20271 GCL-1 Q20271 0.155 14704431 Q9U1W5 Q9N359 GCL-1 CSN-4 0.155 14704431 Q9U1W5 Q9N5D6 GCL-1 UNC-62 0.155 14704431 Q9U373 Q9U1W5 HIS-54 GCL-1 0.033 14704431 Q9U1W5 Q27894 GCL-1 HIS-54 0.126 14704431