PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Uncharacterized protein B0303.7 hipr-1 23549480 intact exp G Uncharacterized protein B0303.7 Uncharacterized protein C09G1.4 23549480 intact exp G ced-6 Uncharacterized protein B0303.7 23549480 intact exp G Uncharacterized protein B0303.7 dyn-1 23549480,19123269 intact exp G SCRM-2 Uncharacterized protein B0303.7 23549480 intact exp G Uncharacterized protein B0303.7 ttm-4 23549480 intact exp G Uncharacterized protein B0303.7 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial 23549480 intact exp G W02C12.3c Uncharacterized protein B0303.7 23549480 intact exp G Uncharacterized protein B0303.7 mig-15 23549480 intact exp G Uncharacterized protein B0303.7 B0336.6 23549480 intact exp G C04A11.4 Uncharacterized protein B0303.7 23549480 intact exp G Uncharacterized protein B0303.7 alx-1 23549480 intact exp G Uncharacterized protein B0303.7 Y62E10A.14 23549480 intact exp Uncharacterized protein B0303.7 Probable multifunctional protein ADE2, AIRC 23549480 intact exp G Uncharacterized protein B0303.7 F29G6.3b 23549480 intact exp G figl-1 Uncharacterized protein B0303.7 23549480 intact exp G Uncharacterized protein B0303.7 R02F2.5 23549480 intact exp Uncharacterized protein B0303.7 Y73F8A.8 23549480 intact exp Uncharacterized protein B0303.7 F09E10.3 23549480 intact exp G Uncharacterized protein B0303.7 unc-84 23549480 intact exp G Uncharacterized protein B0303.7 dyb-1 14704431 biogrid,i2d,mint,intact exp G F56C3.9 Uncharacterized protein B0303.7 23549480 intact exp Uncharacterized protein B0303.7 T11B7.1 23549480 intact exp Uncharacterized protein B0303.7 ZK470.5a 23549480 intact exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9Y048 P34258 two hybrid 14704431 direct interaction X 2 Q9Y048 P34258 two hybrid 14704431 physical association X 2 E3W743 P34258 two hybrid 23549480 physical association X 2 Q10457 P34258 two hybrid 23549480 physical association X 2 G5EDW5 P34258 two hybrid 23549480 physical association X 2 Q23356 P34258 two hybrid 23549480 physical association X 2 Q21648 P34258 two hybrid 23549480 physical association X 2 Q21648 P34258 two hybrid 23549480 physical association X 2 Q17865 P34258 two hybrid 23549480 physical association X 2 Q22387 P34258 two hybrid 23549480 physical association X 2 Q9Y048 P34258 two hybrid pooling approach 14704431 physical association X 2 G5EEQ3 P34258 two hybrid 23549480 physical association X 2 P34258 P34552 two hybrid 23549480 physical association X 2 P34258 Q19749 two hybrid 23549480 physical association X 2 Q10929 P34258 two hybrid 23549480 physical association X 2 O61761 P34258 two hybrid 23549480 physical association X 2 Q5TYL0 P34258 two hybrid 23549480 physical association X 2 O45603 P34258 two hybrid 23549480 physical association X 2 O45603 P34258 two hybrid 23549480 physical association X 2 Q20745 P34258 two hybrid 23549480 physical association X 2 Q95PW9 P34258 two hybrid 23549480 physical association X 2 Q95PW9 P34258 two hybrid 23549480 physical association X 2 Q20330 P34258 two hybrid 23549480 physical association X 2 O16299 P34258 two hybrid 23549480 physical association X 2 O16299 P34258 two hybrid 23549480 physical association X 2 Q9NA61 P34258 two hybrid 23549480 physical association X 2 O76337 P34258 two hybrid 23549480 physical association X 2 Q19246 P34258 two hybrid 23549480 physical association X 2 P34258 P39055 two hybrid pooling approach 19123269 physical association X 2 P34258 P39055 two hybrid array 19123269 physical association X 2 P34258 P39055 two hybrid 23549480 physical association X 2 P34258 P39055 two hybrid 23549480 physical association X 2 P34258 Q02328 two hybrid 23549480 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B B0303.7 ttm-4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23486 bait prey CELE_H02I12.5 B0303.7 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_23484|UniProt_24068 prey|prey bait|bait ced-6 B0303.7 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24066 prey bait B0303.7 R02F2.5 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_23490|UniProt_23487 bait|bait prey|prey B0303.7 C09G1.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24067 bait prey B0303.7 dhs-25 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23489 bait prey B0303.7 hpo-34 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23483 bait prey B0303.7 B0286.3 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24069 bait prey figl-1 B0303.7 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_23482|UniProt_24064 prey|prey bait|bait B0303.7 unc-84 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23485 bait prey B0303.7 F23B12.5 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23491 bait prey CELE_F56C3.9 B0303.7 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24065 prey bait B0303.7 abi-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23495 prey bait B0303.7 hipr-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23492 bait prey B0303.7 alx-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23481 bait prey B0303.7 pqn-90 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24071 bait prey B0303.7 hlh-30 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24070 bait prey B0303.7 dyb-1 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|MI:0471(mint)|(biogrid) DIP_2483|UniProt_30870|MINT_875|BIOGRID_22924 -|prey|prey|prey -|bait|bait|bait B0303.7 nck-1 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_23966|UniProt_24458 prey|prey bait|bait B0303.7 dyn-1 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 19123269,23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact) UniProt_17892|UniProt_24073|UniProt_23480|UniProt_19809 bait|bait|bait|bait prey|prey|prey|prey B0303.7 scrm-2 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24072 bait prey B0303.7 T11B7.1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24074 bait prey B0303.7 mig-15 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23488 bait prey B0303.7 adm-2 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23479 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q19246 P34258 DHS-25 P34258 0.183 23549480 Q5TYL0 P34258 HLH-30 P34258 0.183 23549480 Q10457 P34258 Q10457 P34258 0.183 23549480 Q10929 P34258 ABI-1 P34258 0.183 23549480 P34258 O45603 P34258 O45603 0.183 23549480 Q9Y048 P34258 DYB-1 P34258 0.309 14704431 P39055 P34258 DYN-1 P34258 0.376 19123269,23549480 P34258 E3W743 P34258 HPO-34 0.183 23549480 P34258 G5EDW5 P34258 ADM-2 0.183 23549480 P34258 G5EEQ3 P34258 SCRM-2 0.183 23549480 P34258 O16299 P34258 FIGL-1 0.332 23549480 P34258 O61761 P34258 O61761 0.183 23549480 P34258 O76337 P34258 CED-6 0.183 23549480 P34552 P34258 ALX-1 P34258 0.183 23549480 Q02328 P34258 HIPR-1 P34258 0.183 23549480 Q19749 P34258 Q19749 P34258 0.183 23549480 Q20330 P34258 IFO-1 P34258 0.183 23549480 Q20745 P34258 UNC-84 P34258 0.183 23549480 Q21648 P34258 Q21648 P34258 0.183 23549480 Q22387 P34258 Q22387 P34258 0.183 23549480 Q23356 P34258 MIG-15 P34258 0.183 23549480 Q95PW9 P34258 NCK-1 P34258 0.183 23549480 Q9NA61 P34258 PQN-90 P34258 0.183 23549480 Q17865 P34258 Q17865 P34258 0.183 23549480