PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus T20F5.6 K07D4.7a 23549480 intact exp T20F5.6 tag-170 18692475,unassigned701 biogrid,mint,intact exp G sem-5 T20F5.6 10615043,14704431 biogrid,i2d,mint,intact exp G T20F5.6 F29D10.4 23549480 intact exp G Y37A1B.17a T20F5.6 23549480 intact exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P91482 P29355 - 10615043 - X 2 P91482 P29355 - 12679813 - X 2 P91482 P29355 two hybrid 14704431 direct interaction X 2 Q11183 P91482 two hybrid 18692475 direct interaction X 2 P91482 P29355 two hybrid pooling approach 10615043 physical association X 2 P91482 O76572 two hybrid 23549480 physical association X 2 Q19901 P91482 two hybrid 23549480 physical association X 2 G5ECK4 P91482 two hybrid 23549480 physical association X 2 Q11183 P91482 two hybrid - physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ephx-1 T20F5.6 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23689 bait prey T20F5.6 CELE_Y37A1B.17 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23840 prey bait T20F5.6 tag-170 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint) MINT_3979|UniProt_24711|MINT_3982|MINT_3981|MINT_3984|BIOGRID_28911|MINT_3983|MINT_3980 prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait sem-5 T20F5.6 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0397(two hybrid array) 10615043,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0471(mint)|(intact) BIOGRID_21579|3081|MINT_6904|UniProt_1067 bait|bait|bait|bait prey|prey|prey|prey T20F5.6 hum-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23588 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q19901 P91482 HUM-1 P91482 0.183 23549480 P91482 O76572 P91482 EPHX-1 0.183 23549480 P91482 P29355 P91482 SEM-5 0.126 10615043 Q11183 P91482 TAG-170 P91482 0.332 unassigned701,18692475 P91482 G5ECK4 P91482 G5ECK4 0.183 23549480