iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	UniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UBA	UBA	18347073; 24157867

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UBA	0.0013	18.9	557	590

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGF.dreealqaLraa.nnnleaAve 36
             +  +++MGF ++ ++l+ L+++  +n+ aA++
   Q: 557  KSIHAMMAMGFsNEGAWLTQLLESvQGNISAALD 590
           56889******5555*****************98 PP

Organism

Drosophila melanogaster

Functional Description
(View)

Implicated in sigma rhabdovirus multiplication and necessary for male fertility. Involved in activating transcription of Drs.

Protein Sequence
(Fasta)

MPEKLLKITY QGAGPQKKIN AYLRMPSQNY TILRREIELY LFQERQLPKC DVRTFWIDAD 60
KDEIEIVNQN DYEIFLAKCE SNMHVQVAPL APVEEPKATK QEGSSANAEA PSVDDPSNFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAATCTTTG CCAAAGACCA GCTTTGGCAT TACAATACAA TTTTGGGGAT AGATTAACTA 60
GTGCAGCCCA GCAGGCAGCA CCGTGATTTG CAACAATTTG AGCCTCACTC ATTCAAGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0007005--P:mitochondrion organization
GO:0016239--P:positive regulation of macroautophagy
GO:0030382--P:sperm mitochondrion organization
GO:0006351--P:transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG10360

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001137	Aegilops tauschii	54.29	2.00e-08	53.50
IUUC-Aml-001367	Ailuropoda melanoleuca	48.15	6.00e-10	57.40
IUUC-Atr-003106	Amborella trichopoda	44.44	4.00e-11	62.80
IUUC-Aca-004699	Anolis carolinensis	45.76	4.00e-10	58.50
IUUC-Afu-008992	Aspergillus fumigatus	34.92	2.00e-04	40.40
IUUC-Ani-009220	Aspergillus nidulans	40.91	4.00e-05	42.70
IUUC-Ang-009700	Aspergillus niger	45.45	3.00e-05	43.50
IUUC-Ate-010391	Aspergillus terreus	36.00	3.00e-06	47.40
IUUC-Bgr-012289	Blumeria graminis	34.62	1.00e-08	54.70
IUUC-Bci-013659	Botrytis cinerea	34.29	1.00e-09	58.50
IUUC-Bdi-014362	Brachypodium distachyon	49.02	2.00e-08	54.30
IUUC-Bol-015840	Brassica oleracea	32.00	1.00e-05	44.70
IUUC-Bra-017383	Brassica rapa	42.86	5.00e-06	45.40
IUUC-Cel-018540	Caenorhabditis elegans	45.83	4.00e-11	62.40
IUUC-Cme-027152	Cyanidioschyzon merolae	53.33	9.00e-07	47.80
IUUC-Dno-029060	Dasypus novemcinctus	48.15	5.00e-10	58.20
IUUC-Dor-030547	Dipodomys ordii	42.86	2.00e-09	55.80
IUUC-Eca-033456	Equus caballus	47.17	1.00e-09	56.60
IUUC-Eeu-035157	Erinaceus europaeus	48.98	2.00e-09	55.80
IUUC-Fca-035403	Felis catus	50.00	2.00e-10	59.30
IUUC-Fal-036798	Ficedula albicollis	30.50	1.00e-11	63.20
IUUC-Fox-037985	Fusarium oxysporum	35.71	2.00e-09	57.40
IUUC-Fso-038342	Fusarium solani	34.62	3.00e-09	57.00
IUUC-Ggr-039979	Gaeumannomyces graminis	34.62	8.00e-09	55.50
IUUC-Gga-040137	Gallus gallus	27.81	3.00e-11	62.40
IUUC-Gma-044280	Glycine max	50.00	2.00e-06	47.00
IUUC-Hvu-047302	Hordeum vulgare	54.29	4.00e-08	52.40
IUUC-Itr-048536	Ictidomys tridecemlineatus	42.19	2.00e-09	56.20
IUUC-Lch-049658	Latimeria chalumnae	49.06	3.00e-10	58.90
IUUC-Lpe-051565	Leersia perrieri	42.86	2.00e-07	50.80
IUUC-Loc-052589	Lepisosteus oculatus	47.83	8.00e-09	54.30
IUUC-Mcc-055635	Macaca mulatta	45.28	2.00e-08	53.10
IUUC-Mor-057023	Magnaporthe oryzae	34.62	1.00e-08	55.10
IUUC-Mpo-057400	Magnaporthe poae	34.62	9.00e-09	55.50
IUUC-Mtr-058592	Medicago truncatula	47.50	1.00e-06	48.10
IUUC-Mga-059458	Meleagris gallopavo	39.19	6.00e-10	57.80
IUUC-Mdo-063083	Monodelphis domestica	30.56	2.00e-10	59.70
IUUC-Mac-064456	Musa acuminata	33.33	1.00e-06	48.10
IUUC-Mpu-065727	Mustela putorius furo	48.15	2.00e-10	58.90
IUUC-Mlu-067026	Myotis lucifugus	48.00	1.00e-09	56.20
IUUC-Nfi-068336	Neosartorya fischeri	34.92	2.00e-04	40.80
IUUC-Opr-071091	Ochotona princeps	48.00	5.00e-09	54.70
IUUC-Ont-071864	Oreochromis niloticus	50.00	2.00e-10	59.70
IUUC-Oan-073308	Ornithorhynchus anatinus	28.70	7.00e-10	57.80
IUUC-Oba-075551	Oryza barthii	48.57	2.00e-07	50.40
IUUC-Obr-076023	Oryza brachyantha	48.57	2.00e-06	47.40
IUUC-Ogl-076946	Oryza glaberrima	48.57	2.00e-07	50.40
IUUC-Ogu-078367	Oryza glumaepatula	48.57	2.00e-07	50.40
IUUC-Oin-079583	Oryza indica	48.57	2.00e-07	50.80
IUUC-Olo-080331	Oryza longistaminata	48.57	2.00e-07	50.80
IUUC-Ome-081656	Oryza meridionalis	48.57	2.00e-07	50.80
IUUC-Oni-082599	Oryza nivara	48.57	2.00e-07	50.40
IUUC-Opu-083123	Oryza punctata	48.57	2.00e-07	50.80
IUUC-Oru-085241	Oryza rufipogon	48.57	2.00e-07	50.80
IUUC-Osa-085500	Oryza sativa	48.57	2.00e-07	50.80
IUUC-Olu-087872	Ostreococcus lucimarinus	46.15	2.00e-07	50.10
IUUC-Psi-093925	Pelodiscus sinensis	29.20	2.00e-09	56.20
IUUC-Ppa-095561	Physcomitrella patens	43.86	1.00e-08	53.10
IUUC-Pab-098725	Pongo abelii	45.28	2.00e-08	52.80
IUUC-Pop-099441	Populus trichocarpa	40.32	3.00e-08	53.50
IUUC-Pca-101106	Procavia capensis	49.06	5.00e-10	58.20
IUUC-Ppe-101351	Prunus persica	52.94	5.00e-07	48.90
IUUC-Pva-102710	Pteropus vampyrus	42.86	2.00e-09	56.60
IUUC-Pgr-103390	Puccinia graminis	41.38	1.00e-06	48.90
IUUC-Ptt-103754	Puccinia triticina	39.13	5.00e-07	48.90
IUUC-Sha-107469	Sarcophilus harrisii	33.61	2.00e-10	59.30
IUUC-Ssl-108622	Sclerotinia sclerotiorum	35.71	8.00e-10	58.90
IUUC-Sit-110140	Setaria italica	42.86	2.00e-06	47.80
IUUC-Sly-111749	Solanum lycopersicum	42.50	5.00e-06	45.80
IUUC-Stu-112506	Solanum tuberosum	34.85	3.00e-06	45.80
IUUC-Sbi-114024	Sorghum bicolor	37.78	5.00e-07	49.30
IUUC-Sre-115088	Sporisorium reilianum	34.21	2.70e-02	33.90
IUUC-Tgu-116607	Taeniopygia guttata	30.50	2.00e-11	62.80
IUUC-Tca-120994	Theobroma cacao	41.46	2.00e-06	47.40
IUUC-Tre-122251	Trichoderma reesei	35.71	4.00e-09	56.20
IUUC-Tvi-122314	Trichoderma virens	35.71	3.00e-09	56.60
IUUC-Tae-125905	Triticum aestivum	57.14	1.00e-08	54.70
IUUC-Tur-126096	Triticum urartu	54.29	4.00e-08	52.80
IUUC-Ttr-128676	Tursiops truncatus	47.17	2.00e-09	56.20
IUUC-Vvi-131325	Vitis vinifera	41.86	3.00e-06	46.60
IUUC-Xtr-132907	Xenopus tropicalis	47.06	3.00e-10	58.90
IUUC-Yli-134387	Yarrowia lipolytica	40.00	2.00e-10	59.70

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence