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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105543
Ensembl Protein ID ENSRNOP00000028149.6
UniProt Accession Q501R9; Q9JHG4; NBR1_RAT
Genbank Protein ID AAH95903.1; AAF74120.1; AAF74121.1
Protein Name Next to BRCA1 gene 1 protein; Neighbor of BRCA1 gene 1 protein
Genbank Nucleotide ID BC095903; AF227190; AF227191
Gene Name Nbr1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000020730.7 ENSRNOT00000028149.7 ENSRNOP00000028149.6
ENSRNOG00000020730.7 ENSRNOT00000077942.1 ENSRNOP00000071486.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 23649778; 25412696
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UBA 0.00029 21.3 938 972
ULD/UDP/UFD/PB1 3.50e-18 65.9 4 85
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA
   S: 7    leqlveMGF.dreealqaLraa.nnnleaAveyLl 39
           ++ l eMGF dr+++l+ Lr + +n l++++e+L 
   Q: 938  MAHLFEMGFcDRQLNLRLLRKHnHNILQVVTELLQ 972
           67899*****************9*********996 PP
   

   ULD/UDP/UFD/PB1
   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla.skksllrlliqk 83
           +v+++v++k+e++sf ++ +++++++d++++v+   +++ +++++kY De+++ ++++s+ ++++a+++++ ++ ++l++++++
   Q: 4    QVTLNVTFKNETQSFLVSDPENTTWADVEAMVKV--SFDLNTIQIKYLDEENEEISINSQGEYEEALKMANiKQGNQLQMQVHE 85
           6899******************************..**********************************************97 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
 Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
Protein Sequence
(Fasta)
MEPQVTLNVT FKNETQSFLV SDPENTTWAD VEAMVKVSFD LNTIQIKYLD EENEEISINS 60
QGEYEEALKM ANIKQGNQLQ MQVHEGCHVV DEVLPQTVVE KQATARTGKK PLAHYSSLVR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105543|UBD,UBA;ULD,PB1|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGCTCCAGC CCGACAGCAT GGAACCACAG GTTACTCTAA ATGTGACTTT TAAAAATGAA 60
ACTCAAAGCT TTCTGGTTTC GGATCCAGAA AATACAACTT GGGCTGATGT TGAAGCTATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105543|UBD,UBA;ULD,PB1|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0458--Lysosome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR032350--N_BRCA1_central
IPR033513--NBR1
IPR000270--PB1_dom
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ
PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
Pfam

PF16158--N_BRCA1_IG
PF00564--PB1
PF00569--ZZ
SMART

SM00666--PB1
SM00291--ZnF_ZZ
Gene Ontology

GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005770--C:late endosome
GO:0005764--C:lysosome
GO:0031430--C:M band
GO:0000407--C:pre-autophagosomal structure
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0016236--P:macroautophagy
GO:0051259--P:protein oligomerization
KEGG rno:303554
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002028 Ailuropoda melanoleuca 78.42 0.00e+00 1410.00
IUUC-Atr-003106 Amborella trichopoda 38.46 3.00e-14 73.90
IUUC-Apl-003851 Anas platyrhynchos 55.62 0.00e+00 926.00
IUUC-Aca-005281 Anolis carolinensis 52.48 0.00e+00 844.00
IUUC-Acl-008033 Aspergillus clavatus 25.98 5.00e-16 79.70
IUUC-Afl-008503 Aspergillus flavus 23.15 6.00e-14 72.80
IUUC-Afu-008992 Aspergillus fumigatus 26.91 1.00e-15 79.00
IUUC-Ani-009220 Aspergillus nidulans 23.19 2.00e-14 74.70
IUUC-Aor-010141 Aspergillus oryzae 23.15 6.00e-14 73.20
IUUC-Ate-010391 Aspergillus terreus 26.88 7.00e-15 77.00
IUUC-Ame-010904 Astyanax mexicanus 43.08 1.00e-133 471.00
IUUC-Bgr-011970 Blumeria graminis 30.56 8.00e-10 59.30
IUUC-Bta-013030 Bos taurus 80.99 0.00e+00 1546.00
IUUC-Bol-015840 Brassica oleracea 37.39 5.00e-14 73.20
IUUC-Bra-017383 Brassica rapa 38.26 7.00e-15 75.90
IUUC-Cja-019576 Callithrix jacchus 78.20 0.00e+00 1507.00
IUUC-Cfa-021030 Canis familiaris 78.18 0.00e+00 1463.00
IUUC-Cpo-021386 Cavia porcellus 61.85 0.00e+00 1031.00
IUUC-Csa-023265 Chlorocebus sabaeus 82.29 0.00e+00 1533.00
IUUC-Cho-024901 Choloepus hoffmanni 67.30 6.00e-94 337.00
IUUC-Cne-027045 Cryptococcus neoformans 36.96 1.00e-10 62.40
IUUC-Dre-028204 Danio rerio 43.44 1.00e-135 477.00
IUUC-Dno-028885 Dasypus novemcinctus 79.90 0.00e+00 1498.00
IUUC-Dse-031315 Dothistroma septosporum 28.24 2.00e-11 64.70
IUUC-Eca-033409 Equus caballus 81.68 0.00e+00 1567.00
IUUC-Fca-035407 Felis catus 77.54 0.00e+00 1483.00
IUUC-Fal-037400 Ficedula albicollis 55.46 0.00e+00 946.00
IUUC-Gmo-039454 Gadus morhua 38.07 4.00e-99 355.00
IUUC-Gga-040430 Gallus gallus 61.16 0.00e+00 789.00
IUUC-Gac-042114 Gasterosteus aculeatus 41.73 1.00e-177 617.00
IUUC-Gma-044280 Glycine max 38.33 3.00e-16 80.90
IUUC-Ggo-045643 Gorilla gorilla 85.33 0.00e+00 1187.00
IUUC-Hsa-045869 Homo sapiens 81.39 0.00e+00 1531.00
IUUC-Itr-048172 Ictidomys tridecemlineatus 84.65 0.00e+00 1586.00
IUUC-Lch-050238 Latimeria chalumnae 51.86 0.00e+00 918.00
IUUC-Loc-052860 Lepisosteus oculatus 47.54 5.00e-118 419.00
IUUC-Lma-053158 Leptosphaeria maculans 29.55 1.00e-12 68.60
IUUC-Laf-054460 Loxodonta africana 80.53 0.00e+00 1546.00
IUUC-Mcc-055768 Macaca mulatta 82.26 0.00e+00 1528.00
IUUC-Meu-056136 Macropus eugenii 65.85 0.00e+00 751.00
IUUC-Mor-057101 Magnaporthe oryzae 24.83 8.00e-16 79.30
IUUC-Mtr-058592 Medicago truncatula 38.98 1.00e-14 75.50
IUUC-Mga-059507 Meleagris gallopavo 61.78 0.00e+00 800.00
IUUC-Mvi-060452 Microbotryum violaceum 37.93 2.00e-14 75.10
IUUC-Mmr-060796 Microcebus murinus 82.12 0.00e+00 1410.00
IUUC-Mdo-062214 Monodelphis domestica 71.20 0.00e+00 1370.00
IUUC-Mmu-063788 Mus musculus 91.20 0.00e+00 1760.00
IUUC-Mpu-066809 Mustela putorius furo 78.85 0.00e+00 1460.00
IUUC-Mlu-067887 Myotis lucifugus 81.73 0.00e+00 1531.00
IUUC-Nfi-068336 Neosartorya fischeri 26.91 6.00e-17 83.20
IUUC-Nle-069230 Nomascus leucogenys 81.49 0.00e+00 1526.00
IUUC-Opr-070848 Ochotona princeps 82.84 0.00e+00 708.00
IUUC-Ont-071913 Oreochromis niloticus 43.54 0.00e+00 669.00
IUUC-Oan-073479 Ornithorhynchus anatinus 46.66 1.00e-172 600.00
IUUC-Ocu-074112 Oryctolagus cuniculus 82.34 0.00e+00 1582.00
IUUC-Ola-087486 Oryzias latipes 39.28 2.00e-149 523.00
IUUC-Oga-088832 Otolemur garnettii 81.66 0.00e+00 1497.00
IUUC-Oar-090088 Ovis aries 80.91 0.00e+00 1526.00
IUUC-Ptr-090790 Pan troglodytes 81.55 0.00e+00 1531.00
IUUC-Pan-092523 Papio anubis 82.19 0.00e+00 1529.00
IUUC-Psi-093398 Pelodiscus sinensis 57.35 0.00e+00 1009.00
IUUC-Pno-095009 Phaeosphaeria nodorum 25.42 9.00e-16 79.30
IUUC-Pfo-097491 Poecilia formosa 39.70 9.00e-144 504.00
IUUC-Pab-098775 Pongo abelii 80.77 0.00e+00 1489.00
IUUC-Pca-100690 Procavia capensis 80.83 0.00e+00 763.00
IUUC-Ppe-101351 Prunus persica 40.00 1.00e-16 82.00
IUUC-Pva-102582 Pteropus vampyrus 82.71 0.00e+00 811.00
IUUC-Pgr-103390 Puccinia graminis 38.18 1.00e-10 62.80
IUUC-Ptt-103754 Puccinia triticina 39.62 2.00e-14 74.70
IUUC-Pte-104190 Pyrenophora teres 25.71 1.00e-15 79.30
IUUC-Pyt-104763 Pyrenophora triticirepentis 25.71 8.00e-17 82.80
IUUC-Sha-106861 Sarcophilus harrisii 71.08 0.00e+00 1368.00
IUUC-Ssl-108620 Sclerotinia sclerotiorum 25.64 6.00e-14 73.20
IUUC-Sly-111749 Solanum lycopersicum 38.21 1.00e-16 82.00
IUUC-Stu-111924 Solanum tuberosum 40.16 6.00e-18 86.30
IUUC-Sar-113740 Sorex araneus 73.76 0.00e+00 1274.00
IUUC-Ssc-116108 Sus scrofa 82.89 0.00e+00 1575.00
IUUC-Tgu-117185 Taeniopygia guttata 54.23 0.00e+00 936.00
IUUC-Tru-117624 Takifugu rubripes 43.65 0.00e+00 657.00
IUUC-Tsy-119265 Tarsius syrichta 85.62 0.00e+00 811.00
IUUC-Tni-120728 Tetraodon nigroviridis 44.13 2.00e-138 486.00
IUUC-Tca-120994 Theobroma cacao 36.44 9.00e-15 75.90
IUUC-Tre-122001 Trichoderma reesei 24.07 6.00e-15 76.30
IUUC-Tme-127010 Tuber melanosporum 27.68 2.00e-10 61.20
IUUC-Tbe-127236 Tupaia belangeri 83.38 0.00e+00 1551.00
IUUC-Ttr-128229 Tursiops truncatus 87.29 0.00e+00 828.00
IUUC-Vpa-130650 Vicugna pacos 79.51 2.00e-121 429.00
IUUC-Vvi-131325 Vitis vinifera 38.94 4.00e-18 87.00
IUUC-Xtr-132375 Xenopus tropicalis 47.38 0.00e+00 802.00
IUUC-Xma-134007 Xiphophorus maculatus 40.00 5.00e-143 501.00
IUUC-Zma-134921 Zea mays 38.40 4.00e-17 83.20
Created Date 25-Jun-2017

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