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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046985
Ensembl Protein ID ENSP00000263461.5
UniProt Accession Q9BZH6; Q5VWA1; Q9P2J6; WDR11_HUMAN
Genbank Protein ID AAK08064.1; BAA92589.2; CAH72488.1; CAH72488.1; AAH40469.1; AAH71564.1
Protein Name WD repeat-containing protein 11; Bromodomain and WD repeat-containing protein 2; WD repeat-containing protein 15
Genbank Nucleotide ID AF320223; AB037772; AL391425; AC010998; BC040469; BC071564
Gene Name WDR11; BRWD2; KIAA1351; WDR15
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000120008.15 ENST00000263461.10 ENSP00000263461.5
ENSG00000120008.15 ENST00000605543.5 ENSP00000475076.1
ENSG00000120008.15 ENST00000497136.6 ENSP00000474595.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtBioGRID
mUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-14 54.6 710 737
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf.sdtllvsGsdDgtikvWDl 30
            +s+tc+a+   ++lv G  Dg++  WDl
   Q: 710  MGSITCIAWkG-DTLVLGDMDGNLNFWDL 737
           689******53.679*************8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MLPYTVNFKV SARTLTGALN AHNKAAVDWG WQGLIAYGCH SLVVVIDSIT AQTLQVLEKH 60
KADVVKVKWA RENYHHNIGS PYCLRLASAD VNGKIIVWDV AAGVAQCEIQ EHAKPIQDVQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046985|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCACAACCG CCTAAGCGGC GGAACTCTGG AGAGTGCGGA ACCTAGGATC CTAGGAAACT 60
GAAGGCAACG GAACCTGGGG GCGATGGAAT CCGGGAGCGG TGGAACCCGG AGCCTGTAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046985|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0160--Chromosomal rearrangement
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0225--Disease mutation
KW-1016--Hypogonadotropic hypogonadism
KW-0956--Kallmann syndrome
KW-0472--Membrane
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005765--C:lysosomal membrane
GO:0016020--C:membrane
GO:0015630--C:microtubule cytoskeleton
GO:0005634--C:nucleus
KEGG hsa:55717
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001973 Ailuropoda melanoleuca 95.44 0.00e+00 2252.00
IUUC-Apl-003487 Anas platyrhynchos 87.55 0.00e+00 2013.00
IUUC-Aca-005128 Anolis carolinensis 86.48 0.00e+00 2098.00
IUUC-Ame-010938 Astyanax mexicanus 72.57 0.00e+00 1706.00
IUUC-Bta-013239 Bos taurus 96.56 0.00e+00 2264.00
IUUC-Cja-019424 Callithrix jacchus 98.12 0.00e+00 2298.00
IUUC-Cfa-020723 Canis familiaris 96.16 0.00e+00 2294.00
IUUC-Cpo-021768 Cavia porcellus 95.83 0.00e+00 2233.00
IUUC-Csa-023563 Chlorocebus sabaeus 99.26 0.00e+00 2319.00
IUUC-Cho-024395 Choloepus hoffmanni 85.59 0.00e+00 1718.00
IUUC-Dre-027774 Danio rerio 76.72 0.00e+00 1869.00
IUUC-Dno-029488 Dasypus novemcinctus 94.63 0.00e+00 2275.00
IUUC-Dor-030502 Dipodomys ordii 94.07 0.00e+00 1526.00
IUUC-Ete-032425 Echinops telfairi 83.92 0.00e+00 1943.00
IUUC-Eca-034402 Equus caballus 95.76 0.00e+00 2284.00
IUUC-Eeu-034955 Erinaceus europaeus 89.78 0.00e+00 1979.00
IUUC-Fca-036394 Felis catus 94.63 0.00e+00 2247.00
IUUC-Fal-037371 Ficedula albicollis 88.40 0.00e+00 1816.00
IUUC-Gmo-039210 Gadus morhua 76.01 0.00e+00 1459.00
IUUC-Gga-040395 Gallus gallus 86.20 0.00e+00 2077.00
IUUC-Gac-042195 Gasterosteus aculeatus 70.20 0.00e+00 1707.00
IUUC-Ggo-045386 Gorilla gorilla 94.23 0.00e+00 1242.00
IUUC-Itr-048364 Ictidomys tridecemlineatus 95.48 0.00e+00 1244.00
IUUC-Lch-050581 Latimeria chalumnae 80.71 0.00e+00 2000.00
IUUC-Loc-052155 Lepisosteus oculatus 76.59 0.00e+00 1874.00
IUUC-Laf-053831 Loxodonta africana 94.51 0.00e+00 2313.00
IUUC-Mcc-055060 Macaca mulatta 99.26 0.00e+00 2323.00
IUUC-Meu-056066 Macropus eugenii 76.56 0.00e+00 1145.00
IUUC-Mga-059918 Meleagris gallopavo 86.69 0.00e+00 2040.00
IUUC-Mmr-061315 Microcebus murinus 96.70 0.00e+00 2244.00
IUUC-Mdo-062584 Monodelphis domestica 91.76 0.00e+00 2212.00
IUUC-Mmu-063106 Mus musculus 94.28 0.00e+00 2316.00
IUUC-Mpu-065981 Mustela putorius furo 96.34 0.00e+00 2173.00
IUUC-Mlu-066992 Myotis lucifugus 89.98 0.00e+00 2207.00
IUUC-Nle-069873 Nomascus leucogenys 99.01 0.00e+00 2300.00
IUUC-Opr-071105 Ochotona princeps 92.84 0.00e+00 1786.00
IUUC-Ont-071707 Oreochromis niloticus 77.04 0.00e+00 1920.00
IUUC-Oan-073195 Ornithorhynchus anatinus 89.79 0.00e+00 1980.00
IUUC-Ocu-074314 Oryctolagus cuniculus 95.02 0.00e+00 2202.00
IUUC-Ola-087220 Oryzias latipes 75.10 0.00e+00 1868.00
IUUC-Oga-088522 Otolemur garnettii 95.97 0.00e+00 2281.00
IUUC-Oar-090343 Ovis aries 96.31 0.00e+00 2255.00
IUUC-Ptr-090747 Pan troglodytes 100.00 0.00e+00 2318.00
IUUC-Pan-091747 Papio anubis 99.01 0.00e+00 2318.00
IUUC-Psi-093610 Pelodiscus sinensis 85.20 0.00e+00 2076.00
IUUC-Pfo-096429 Poecilia formosa 76.40 0.00e+00 1869.00
IUUC-Pab-097534 Pongo abelii 99.06 0.00e+00 1261.00
IUUC-Pca-100937 Procavia capensis 89.62 0.00e+00 2126.00
IUUC-Pva-102688 Pteropus vampyrus 89.52 0.00e+00 1928.00
IUUC-Rno-106056 Rattus norvegicus 94.11 0.00e+00 2345.00
IUUC-Sha-107611 Sarcophilus harrisii 91.82 0.00e+00 1946.00
IUUC-Smo-108681 Selaginella moellendorffii 22.97 1.00e-60 228.00
IUUC-Ssc-116007 Sus scrofa 95.35 0.00e+00 2279.00
IUUC-Tgu-116906 Taeniopygia guttata 87.11 0.00e+00 1982.00
IUUC-Tru-117693 Takifugu rubripes 76.02 0.00e+00 1892.00
IUUC-Tsy-119556 Tarsius syrichta 83.54 0.00e+00 1910.00
IUUC-Tni-120586 Tetraodon nigroviridis 76.21 0.00e+00 1887.00
IUUC-Tbe-127341 Tupaia belangeri 91.22 0.00e+00 2160.00
IUUC-Ttr-128750 Tursiops truncatus 93.46 0.00e+00 2172.00
IUUC-Vpa-130642 Vicugna pacos 87.56 0.00e+00 1488.00
IUUC-Xtr-132718 Xenopus tropicalis 79.08 0.00e+00 1943.00
Created Date 25-Jun-2017

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