iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	CGAP	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	TCGA	ICGC	THPA
HPM
DNA & RNA Element
microRNA	TRANSFAC	RepTar	miRcode
RAID2
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
InWeb_IM
Protein 3D Structure
PDB	MMDB
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-11	44.8	837	898

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqn......ddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + ++y+y++ +      ++eL l++Gd +++   +  + g  +g+    g+rGl+P+nFve++ 
   Q: 837  FMAQYNYNPFEgpndhpEGELPLTAGDYIYIF-GDMDEDGFYEGE-LEDGRRGLVPSNFVEQIP 898
           5677777663222223379************9.9999*******5.889************985 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MAKDSPSPLG ASPKKPGCSS PAAAVLENQR RELEKLRAEL EAERAGWRAE RRRFAARERQ 60
LREEAERERR QLADRLRSKW EAQRSRELRQ LQEEMQRERE AEIRQLLRWK EAEQRQLQQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCCACCT GACCCAAATA CACCACCTGA ACCCACGACC AGGTATGCCC ACACCCCATG 60
GGTGGCCTTA ACACACACAC CCTGCCCCTT TCTCCAAGTA CAGGAGCAGC AGCCCAGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50853--FN3
PS50002--SH3

Pfam

PF07653--SH3_2
PF14604--SH3_9

SMART

SM00326--SH3

KEGG

hsa:85376

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001623	Ailuropoda melanoleuca	68.05	0.00e+00	1773.00
IUUC-Cja-018830	Callithrix jacchus	82.51	0.00e+00	2251.00
IUUC-Cpo-021571	Cavia porcellus	63.09	0.00e+00	1570.00
IUUC-Dno-029522	Dasypus novemcinctus	66.43	0.00e+00	1747.00
IUUC-Meu-056071	Macropus eugenii	46.22	3.00e-149	522.00
IUUC-Mdo-062621	Monodelphis domestica	40.36	2.00e-142	500.00
IUUC-Mpu-065689	Mustela putorius furo	67.73	0.00e+00	1766.00
IUUC-Mlu-067063	Myotis lucifugus	66.86	0.00e+00	1736.00
IUUC-Pab-097875	Pongo abelii	94.30	0.00e+00	2586.00
IUUC-Pva-102342	Pteropus vampyrus	71.20	0.00e+00	1726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence