iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000017180.2	ENSLACT00000026314.1	ENSLACP00000022176.1
ENSLACG00000017180.2	ENSLACT00000019675.1	ENSLACP00000019537.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-10	41.5	174	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +++ +lydy++ +  ++ l kG+  +vi  ee ++ W+k+ ++ +g++G +P+n+v+++
   Q: 174  TKVIVALYDYKPMEALDMPLVKGEEYYVI--EEANAQWWKA-RDKNGQEGYIPSNYVTEA 230
           567889***********************..999*******.5**************987 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MNMTLNEGKK GSKKGSVDVD KISCVETVAP EENPPPERQI LRKGDDMVEM EQISVIERFP 60
YPFQIIYDEG PLYIFAPTEE LRQRWIKELK NVTRFNKDLA QKYHPCFWID GEWLCCKQIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCTGGGC TCAGAACTGT AGCAGAAGCA ATGTCGAGTG TCATTTTAGA GAGTATCTTC 60
CTTAAGAGGT CCCAACAGAA GAAAAAGACT TCCCCCCTGA ACTTTAAAAA GAGGCTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR001562--Znf_Btk_motif

PROSITE

PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
PS51113--ZF_BTK

Pfam

PF00779--BTK
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00107--BTK
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0035556--P:intracellular signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001365	Ailuropoda melanoleuca	75.45	0.00e+00	972.00
IUUC-Apl-003907	Anas platyrhynchos	74.26	0.00e+00	942.00
IUUC-Aca-004978	Anolis carolinensis	72.22	0.00e+00	920.00
IUUC-Bta-012467	Bos taurus	75.29	0.00e+00	971.00
IUUC-Cja-018841	Callithrix jacchus	74.59	0.00e+00	964.00
IUUC-Cfa-020983	Canis familiaris	75.12	0.00e+00	962.00
IUUC-Cpo-021307	Cavia porcellus	74.76	0.00e+00	969.00
IUUC-Csa-023508	Chlorocebus sabaeus	74.75	0.00e+00	782.00
IUUC-Dno-029828	Dasypus novemcinctus	74.14	0.00e+00	947.00
IUUC-Dor-030102	Dipodomys ordii	69.02	0.00e+00	846.00
IUUC-Ete-032981	Echinops telfairi	67.81	0.00e+00	847.00
IUUC-Eca-033594	Equus caballus	75.29	0.00e+00	970.00
IUUC-Eeu-035281	Erinaceus europaeus	71.03	0.00e+00	741.00
IUUC-Fca-035495	Felis catus	74.96	0.00e+00	960.00
IUUC-Fal-036719	Ficedula albicollis	75.41	0.00e+00	976.00
IUUC-Gga-041193	Gallus gallus	74.06	0.00e+00	941.00
IUUC-Gma-043813	Glycine max	31.22	4.00e-18	86.30
IUUC-Hsa-045931	Homo sapiens	74.63	0.00e+00	959.00
IUUC-Itr-048061	Ictidomys tridecemlineatus	75.78	0.00e+00	975.00
IUUC-Laf-053516	Loxodonta africana	74.71	0.00e+00	984.00
IUUC-Mcc-054795	Macaca mulatta	74.27	0.00e+00	960.00
IUUC-Meu-056157	Macropus eugenii	65.63	0.00e+00	819.00
IUUC-Mga-059529	Meleagris gallopavo	74.77	0.00e+00	863.00
IUUC-Mmr-060824	Microcebus murinus	74.40	0.00e+00	907.00
IUUC-Mdo-063036	Monodelphis domestica	75.97	0.00e+00	958.00
IUUC-Mmu-064047	Mus musculus	75.45	0.00e+00	971.00
IUUC-Mpu-066810	Mustela putorius furo	75.78	0.00e+00	975.00
IUUC-Mlu-067671	Myotis lucifugus	74.47	0.00e+00	962.00
IUUC-Nle-069108	Nomascus leucogenys	74.63	0.00e+00	961.00
IUUC-Opr-070505	Ochotona princeps	59.47	1.00e-156	546.00
IUUC-Oan-073495	Ornithorhynchus anatinus	74.35	0.00e+00	990.00
IUUC-Ocu-074416	Oryctolagus cuniculus	74.59	0.00e+00	971.00
IUUC-Oga-088995	Otolemur garnettii	74.23	0.00e+00	959.00
IUUC-Oar-089632	Ovis aries	73.98	0.00e+00	954.00
IUUC-Ptr-090941	Pan troglodytes	74.63	0.00e+00	960.00
IUUC-Pan-091900	Papio anubis	71.99	0.00e+00	923.00
IUUC-Psi-093048	Pelodiscus sinensis	73.17	0.00e+00	912.00
IUUC-Pab-097587	Pongo abelii	74.80	0.00e+00	961.00
IUUC-Pca-100374	Procavia capensis	63.09	8.00e-112	397.00
IUUC-Pva-102583	Pteropus vampyrus	75.12	0.00e+00	948.00
IUUC-Rno-104868	Rattus norvegicus	71.94	0.00e+00	908.00
IUUC-Sha-106744	Sarcophilus harrisii	75.45	0.00e+00	986.00
IUUC-Sar-113041	Sorex araneus	75.21	0.00e+00	919.00
IUUC-Ssc-115294	Sus scrofa	75.08	0.00e+00	971.00
IUUC-Tsy-118945	Tarsius syrichta	77.18	0.00e+00	713.00
IUUC-Ttr-128769	Tursiops truncatus	67.43	0.00e+00	853.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence