iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072585

Ensembl Protein ID

ENSONIP00000014659.1

UniProt Accession

I3K0L4; I3K0L4_ORENI

Genbank Protein ID

ENSONIP00000014659

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01041388

Gene Name

TXK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000011645.1	ENSONIT00000014671.1	ENSONIP00000014659.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.80e-12	46.4	76	128

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           v ++yd++a++d +Ltlk+G+   ++  ++qd+ W++++ + +g +G++P+n+v++
   Q: 76   VVAMYDFTAKEDTDLTLKQGEEYIIL--HKQDQLWWRAQ-DKHGNKGFIPSNYVTE 128
           789*******************9999..9*********7.**************87 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MIHSNHSIRS IICCCCAVQT REFSTRVELE SRTSLCFPNR RYSGQPTRLQ VERSRRKLPL 60
PPPEGEDGEG EGLLSVVAMY DFTAKEDTDL TLKQGEEYII LHKQDQLWWR AQDKHGNKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGTGTGTG TGTGTGTGTG TGTGTGCACT CTTCCTGGAG ATATTCACAT AGACGGATGC 60
TTTGTGGTTT CATTCACGTC ATTCTTTCAC TTCCTTTCTG TATCTTTGTC TTCATCTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001365	Ailuropoda melanoleuca	57.98	2.00e-160	559.00
IUUC-Apl-003669	Anas platyrhynchos	65.69	1.00e-173	603.00
IUUC-Aca-004978	Anolis carolinensis	57.60	1.00e-153	536.00
IUUC-Ame-010694	Astyanax mexicanus	65.23	0.00e+00	659.00
IUUC-Bta-012467	Bos taurus	58.43	9.00e-161	560.00
IUUC-Cja-018841	Callithrix jacchus	58.37	3.00e-160	558.00
IUUC-Cfa-020983	Canis familiaris	58.20	1.00e-160	560.00
IUUC-Cpo-021307	Cavia porcellus	58.65	2.00e-161	563.00
IUUC-Csa-023508	Chlorocebus sabaeus	58.20	2.00e-161	562.00
IUUC-Dre-028544	Danio rerio	74.50	0.00e+00	629.00
IUUC-Dno-029828	Dasypus novemcinctus	57.70	1.00e-161	563.00
IUUC-Dor-030102	Dipodomys ordii	56.18	1.00e-147	516.00
IUUC-Ete-032981	Echinops telfairi	50.23	1.00e-128	454.00
IUUC-Eca-033594	Equus caballus	58.20	1.00e-160	560.00
IUUC-Eeu-035281	Erinaceus europaeus	55.45	4.00e-108	385.00
IUUC-Fca-035495	Felis catus	58.43	2.00e-161	562.00
IUUC-Fal-036771	Ficedula albicollis	65.46	2.00e-172	598.00
IUUC-Gga-041193	Gallus gallus	58.24	9.00e-160	557.00
IUUC-Gac-042383	Gasterosteus aculeatus	72.36	0.00e+00	725.00
IUUC-Hsa-045931	Homo sapiens	58.20	1.00e-160	560.00
IUUC-Itr-048061	Ictidomys tridecemlineatus	58.20	1.00e-160	560.00
IUUC-Lch-050516	Latimeria chalumnae	68.62	3.00e-177	615.00
IUUC-Loc-052730	Lepisosteus oculatus	66.73	0.00e+00	730.00
IUUC-Laf-053516	Loxodonta africana	58.43	3.00e-161	561.00
IUUC-Mcc-054795	Macaca mulatta	58.20	8.00e-161	560.00
IUUC-Meu-056157	Macropus eugenii	60.99	2.00e-141	496.00
IUUC-Mga-060196	Meleagris gallopavo	66.07	3.00e-178	618.00
IUUC-Mmr-060824	Microcebus murinus	58.20	3.00e-161	561.00
IUUC-Mdo-062054	Monodelphis domestica	68.85	0.00e+00	629.00
IUUC-Mmu-064047	Mus musculus	58.65	1.00e-161	563.00
IUUC-Mpu-066786	Mustela putorius furo	68.17	9.00e-180	623.00
IUUC-Mlu-067671	Myotis lucifugus	57.98	1.00e-153	536.00
IUUC-Nle-069108	Nomascus leucogenys	58.20	5.00e-161	561.00
IUUC-Opr-070505	Ochotona princeps	45.56	9.00e-110	390.00
IUUC-Oan-073495	Ornithorhynchus anatinus	58.20	1.00e-160	560.00
IUUC-Ocu-074416	Oryctolagus cuniculus	58.20	2.00e-160	559.00
IUUC-Ola-086938	Oryzias latipes	85.32	0.00e+00	784.00
IUUC-Oga-088995	Otolemur garnettii	58.65	2.00e-161	562.00
IUUC-Oar-089632	Ovis aries	58.43	7.00e-161	560.00
IUUC-Ptr-090941	Pan troglodytes	57.98	2.00e-160	559.00
IUUC-Pan-091900	Papio anubis	56.63	3.00e-152	532.00
IUUC-Psi-093565	Pelodiscus sinensis	65.62	4.00e-174	604.00
IUUC-Pfo-096955	Poecilia formosa	83.30	0.00e+00	889.00
IUUC-Pab-097587	Pongo abelii	58.20	4.00e-161	561.00
IUUC-Pva-102583	Pteropus vampyrus	57.75	4.00e-153	535.00
IUUC-Rno-104868	Rattus norvegicus	57.17	2.00e-154	539.00
IUUC-Sha-106744	Sarcophilus harrisii	59.33	9.00e-164	570.00
IUUC-Sar-113041	Sorex araneus	59.10	5.00e-155	541.00
IUUC-Ssc-115294	Sus scrofa	58.20	8.00e-161	560.00
IUUC-Tgu-116458	Taeniopygia guttata	65.46	2.00e-175	609.00
IUUC-Tsy-118945	Tarsius syrichta	58.87	1.00e-152	533.00
IUUC-Ttr-128769	Tursiops truncatus	53.93	1.00e-144	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence