iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000060550.1	ENSRNOT00000087102.1	ENSRNOP00000070453.1
ENSRNOG00000060550.1	ENSRNOT00000085703.1	ENSRNOP00000074461.1
ENSRNOG00000060550.1	ENSRNOT00000091963.1	ENSRNOP00000073697.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
iRefIndex
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	UniProt
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UIM	UIM	11919637

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UIM	0.00047	20.4	218	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +E+++LqlAla+S++++e+
   Q: 218  EEELQLQLALAMSREVAEQ 236
           79***************98 PP

Organism

Rattus norvegicus

Functional Description
(View)

Plays a role in the formation of clathrin-coated invaginations and endocytosis.

Protein Sequence
(Fasta)

MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMV 60
WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI FAIQTLKDFQ YIDRDGKDQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTGGGTGT CAAACGCTGC ACGGGCTCGG GTCGCTCCCG CCTCTCCAGC GTCGCCGGCG 60
GCTGCAGCCT TGCACTCGCG CTGGCCGGGA ACAGAGGTGA GCCGGGACTC GCGGGGCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0446--Lipid-binding
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation

Interpro

IPR013809--ENTH
IPR008942--ENTH_VHS
IPR027319--Epsin-2_metazoa
IPR003903--UIM_dom

PROSITE

PS50942--ENTH
PS50330--UIM

Pfam

PF01417--ENTH

SMART

SM00273--ENTH
SM00726--UIM

Gene Ontology

GO:0030128--C:clathrin coat of endocytic vesicle
GO:0008289--F:lipid binding
GO:0006897--P:endocytosis
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000113	Aegilops tauschii	49.32	2.00e-41	164.00
IUUC-Aml-001209	Ailuropoda melanoleuca	85.23	0.00e+00	850.00
IUUC-Apl-003474	Anas platyrhynchos	62.84	0.00e+00	657.00
IUUC-Aca-005348	Anolis carolinensis	70.25	0.00e+00	680.00
IUUC-Aly-006457	Arabidopsis lyrata	47.17	1.00e-41	164.00
IUUC-Ath-007675	Arabidopsis thaliana	47.17	8.00e-42	165.00
IUUC-Ago-007986	Ashbya gossypii	46.75	4.00e-39	155.00
IUUC-Ate-010292	Aspergillus terreus	53.79	3.00e-39	156.00
IUUC-Ame-011423	Astyanax mexicanus	61.91	4.00e-140	491.00
IUUC-Bta-013258	Bos taurus	73.64	0.00e+00	712.00
IUUC-Bdi-014129	Brachypodium distachyon	48.37	3.00e-42	167.00
IUUC-Bol-016058	Brassica oleracea	47.17	6.00e-42	166.00
IUUC-Bra-017893	Brassica rapa	47.17	1.00e-41	165.00
IUUC-Cel-018350	Caenorhabditis elegans	45.11	1.00e-81	296.00
IUUC-Cja-019818	Callithrix jacchus	83.90	0.00e+00	833.00
IUUC-Cfa-020229	Canis familiaris	82.68	0.00e+00	813.00
IUUC-Cpo-022174	Cavia porcellus	86.10	0.00e+00	812.00
IUUC-Csa-023789	Chlorocebus sabaeus	86.78	0.00e+00	862.00
IUUC-Cho-024649	Choloepus hoffmanni	61.29	3.00e-56	213.00
IUUC-Cin-025755	Ciona intestinalis	69.16	4.00e-85	306.00
IUUC-Csv-025907	Ciona savignyi	43.43	2.00e-96	346.00
IUUC-Cgl-026614	Colletotrichum gloeosporioides	55.26	2.00e-46	180.00
IUUC-Cne-027047	Cryptococcus neoformans	57.81	1.00e-41	164.00
IUUC-Cme-027132	Cyanidioschyzon merolae	34.97	1.00e-24	107.00
IUUC-Dre-028037	Danio rerio	60.77	8.00e-143	500.00
IUUC-Dno-029660	Dasypus novemcinctus	71.84	1.00e-179	623.00
IUUC-Dor-030230	Dipodomys ordii	89.64	8.00e-116	410.00
IUUC-Dme-032149	Drosophila melanogaster	52.15	1.00e-89	324.00
IUUC-Ete-032944	Echinops telfairi	91.03	1.00e-116	414.00
IUUC-Eca-033636	Equus caballus	67.24	0.00e+00	706.00
IUUC-Eeu-034601	Erinaceus europaeus	74.17	3.00e-98	352.00
IUUC-Fca-036004	Felis catus	75.62	0.00e+00	722.00
IUUC-Fal-036640	Ficedula albicollis	73.27	0.00e+00	740.00
IUUC-Fox-037900	Fusarium oxysporum	39.71	2.00e-33	137.00
IUUC-Gmo-038468	Gadus morhua	61.98	5.00e-132	464.00
IUUC-Gga-040781	Gallus gallus	73.40	0.00e+00	768.00
IUUC-Gac-042432	Gasterosteus aculeatus	60.57	1.00e-142	499.00
IUUC-Gma-042967	Glycine max	49.06	2.00e-43	171.00
IUUC-Ggo-044421	Gorilla gorilla	80.36	8.00e-126	444.00
IUUC-Hsa-045740	Homo sapiens	80.36	3.00e-126	445.00
IUUC-Hvu-047135	Hordeum vulgare	48.37	6.00e-42	166.00
IUUC-Itr-048090	Ictidomys tridecemlineatus	83.29	2.00e-144	505.00
IUUC-Lch-049618	Latimeria chalumnae	68.20	0.00e+00	683.00
IUUC-Lpe-051296	Leersia perrieri	49.02	2.00e-43	171.00
IUUC-Loc-051728	Lepisosteus oculatus	66.73	1.00e-163	569.00
IUUC-Laf-053389	Loxodonta africana	77.53	0.00e+00	731.00
IUUC-Mcc-055565	Macaca mulatta	97.99	4.00e-116	412.00
IUUC-Mga-060111	Meleagris gallopavo	73.96	0.00e+00	772.00
IUUC-Mvi-060293	Microbotryum violaceum	54.19	6.00e-48	185.00
IUUC-Mmr-060793	Microcebus murinus	90.87	9.00e-117	414.00
IUUC-Mdo-061941	Monodelphis domestica	71.43	0.00e+00	711.00
IUUC-Mmu-064004	Mus musculus	93.51	4.00e-157	548.00
IUUC-Mpu-066625	Mustela putorius furo	89.95	1.00e-115	410.00
IUUC-Mlu-068085	Myotis lucifugus	70.59	0.00e+00	677.00
IUUC-Ncr-068627	Neurospora crassa	37.83	1.00e-38	154.00
IUUC-Nle-069825	Nomascus leucogenys	79.85	3.00e-125	442.00
IUUC-Opr-070492	Ochotona princeps	77.75	1.00e-92	333.00
IUUC-Ont-072355	Oreochromis niloticus	57.24	2.00e-138	486.00
IUUC-Oan-073743	Ornithorhynchus anatinus	76.55	0.00e+00	773.00
IUUC-Ocu-074139	Oryctolagus cuniculus	80.16	0.00e+00	683.00
IUUC-Oba-075922	Oryza barthii	49.02	2.00e-43	171.00
IUUC-Obr-076552	Oryza brachyantha	48.37	9.00e-43	169.00
IUUC-Ogl-077885	Oryza glaberrima	49.02	2.00e-43	171.00
IUUC-Ogu-078795	Oryza glumaepatula	49.02	1.00e-43	171.00
IUUC-Oin-080196	Oryza indica	49.02	2.00e-43	171.00
IUUC-Olo-080509	Oryza longistaminata	49.02	1.00e-43	171.00
IUUC-Ome-081531	Oryza meridionalis	49.02	1.00e-43	171.00
IUUC-Oni-083003	Oryza nivara	49.02	2.00e-43	171.00
IUUC-Opu-083829	Oryza punctata	49.02	2.00e-43	171.00
IUUC-Oru-084248	Oryza rufipogon	49.02	2.00e-43	171.00
IUUC-Osa-085910	Oryza sativa	49.02	2.00e-43	171.00
IUUC-Ola-087087	Oryzias latipes	86.15	8.00e-93	334.00
IUUC-Olu-087896	Ostreococcus lucimarinus	35.21	7.00e-18	83.60
IUUC-Oga-088870	Otolemur garnettii	85.59	0.00e+00	866.00
IUUC-Oar-090233	Ovis aries	88.39	7.00e-117	414.00
IUUC-Ptr-091026	Pan troglodytes	80.36	9.00e-126	444.00
IUUC-Pan-092050	Papio anubis	86.78	0.00e+00	832.00
IUUC-Psi-093688	Pelodiscus sinensis	72.46	0.00e+00	774.00
IUUC-Pma-094335	Petromyzon marinus	60.54	7.00e-146	510.00
IUUC-Pfo-096650	Poecilia formosa	53.48	5.00e-116	411.00
IUUC-Pab-098209	Pongo abelii	80.61	2.00e-135	476.00
IUUC-Pop-098881	Populus trichocarpa	49.02	1.00e-42	168.00
IUUC-Pca-100479	Procavia capensis	70.28	0.00e+00	724.00
IUUC-Ppe-101157	Prunus persica	49.02	7.00e-42	166.00
IUUC-Pva-102177	Pteropus vampyrus	75.51	1.00e-110	393.00
IUUC-Ptt-103708	Puccinia triticina	53.95	5.00e-41	161.00
IUUC-Sce-106344	Saccharomyces cerevisiae	52.67	8.00e-37	147.00
IUUC-Sha-107254	Sarcophilus harrisii	72.26	0.00e+00	760.00
IUUC-Sit-109784	Setaria italica	49.02	8.00e-43	169.00
IUUC-Sly-111438	Solanum lycopersicum	47.80	5.00e-43	169.00
IUUC-Stu-112874	Solanum tuberosum	47.80	4.00e-43	170.00
IUUC-Sar-113696	Sorex araneus	97.49	4.00e-116	412.00
IUUC-Sbi-114540	Sorghum bicolor	47.71	4.00e-42	167.00
IUUC-Sre-114959	Sporisorium reilianum	55.97	8.00e-43	167.00
IUUC-Tgu-117391	Taeniopygia guttata	80.45	0.00e+00	746.00
IUUC-Tru-117791	Takifugu rubripes	46.59	6.00e-94	338.00
IUUC-Tsy-119034	Tarsius syrichta	62.82	4.00e-60	226.00
IUUC-Tni-120827	Tetraodon nigroviridis	60.49	7.00e-149	520.00
IUUC-Tca-121377	Theobroma cacao	48.10	1.00e-42	168.00
IUUC-Tae-122690	Triticum aestivum	48.37	4.00e-42	166.00
IUUC-Tur-126042	Triticum urartu	48.37	4.00e-42	166.00
IUUC-Tbe-127405	Tupaia belangeri	89.50	3.00e-115	408.00
IUUC-Ttr-128595	Tursiops truncatus	67.82	8.00e-128	451.00
IUUC-Uma-129605	Ustilago maydis	58.40	9.00e-43	167.00
IUUC-Vpa-130825	Vicugna pacos	61.68	1.00e-60	227.00
IUUC-Vvi-131209	Vitis vinifera	47.83	3.00e-41	162.00
IUUC-Xtr-132334	Xenopus tropicalis	66.83	0.00e+00	640.00
IUUC-Xma-134173	Xiphophorus maculatus	53.06	9.00e-128	450.00
IUUC-Yli-134375	Yarrowia lipolytica	50.00	3.00e-39	156.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence