iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091093

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03020702

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000013054.5	ENSPTRT00000024205.5	ENSPTRP00000022327.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.20e-79	266.2	54	493

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+++l+++++++++e  +
   Q: 54   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDakvrIIPLQLQRLFAQLLLLDQEAASTTDLTDSFGWTSNE--E 140
           9*****************************888888765543322234448999******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+r+e+fldl+++
   Q: 141  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQIVCKECKNVSERQEDFLDLTVA 203
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 204  VKNVS-----GLEDALwNMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 287
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  +++Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 288  FCEQSELDDL-EYIYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeekskpdvnlkdlqseeeidhpliilkailleennlipvdq 375
           ****999987.9***************************************************************************** PP
   S: 302  .............................................................................ekgk.....Wll 308
                                                                                        +  +     W+ 
   Q: 376  lgqkllkkigiswnkkyrkqhgplrkflqlhsqifllssdestvrllknsslqaesdfqrndqqifkmlppespglnN--SiscphWFD 462
           ******************************************************999999999999999888887651..234567*** PP
   S: 309  fdDskVtevkeeevleetg..staYvlfYkr 337
           ++DskV++++e++++++ +  ++aY+lfY++
   Q: 463  INDSKVQPIREKDIEQQFQgkESAYMLFYRK 493
           ****************9889*********98 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSLFLRVVFS FTMFGDLFEE EYSTVSNNQY GKGKKLKTKA LEPPAPREFT NLSGIRNQGG 60
TCYLNSLLQT LHFTPEFREA LFSLGPEELG LFEDKDKPDA KVRIIPLQLQ RLFAQLLLLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCACTTT TTTTAAGGGT AGTATTTAGT TTCACAATGT TTGGGGACCT ATTTGAAGAG 60
GAGTATTCCA CTGTGTCTAA TAATCAGTAT GGAAAAGGGA AGAAATTAAA GACTAAAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	84.55	0.00e+00	1977.00
IUUC-Apl-004105	Anas platyrhynchos	64.49	0.00e+00	1556.00
IUUC-Aca-004715	Anolis carolinensis	62.59	0.00e+00	1490.00
IUUC-Ame-011073	Astyanax mexicanus	47.74	0.00e+00	1030.00
IUUC-Bta-012487	Bos taurus	83.50	0.00e+00	2030.00
IUUC-Cja-018937	Callithrix jacchus	94.58	0.00e+00	2328.00
IUUC-Cfa-020645	Canis familiaris	79.82	0.00e+00	1269.00
IUUC-Cpo-022160	Cavia porcellus	80.13	0.00e+00	1964.00
IUUC-Csa-023078	Chlorocebus sabaeus	95.71	0.00e+00	2398.00
IUUC-Cho-025013	Choloepus hoffmanni	67.03	0.00e+00	845.00
IUUC-Csv-026193	Ciona savignyi	56.47	6.00e-59	220.00
IUUC-Dre-027416	Danio rerio	48.42	0.00e+00	1129.00
IUUC-Dno-029639	Dasypus novemcinctus	80.82	0.00e+00	1686.00
IUUC-Dor-030624	Dipodomys ordii	91.00	3.00e-155	542.00
IUUC-Ete-032626	Echinops telfairi	63.90	0.00e+00	756.00
IUUC-Eca-034208	Equus caballus	85.99	0.00e+00	2129.00
IUUC-Eeu-035340	Erinaceus europaeus	46.36	5.00e-94	339.00
IUUC-Fca-035886	Felis catus	74.47	0.00e+00	785.00
IUUC-Fal-036925	Ficedula albicollis	64.14	0.00e+00	1459.00
IUUC-Gmo-038597	Gadus morhua	46.04	0.00e+00	892.00
IUUC-Gga-041171	Gallus gallus	64.18	0.00e+00	1557.00
IUUC-Gac-041362	Gasterosteus aculeatus	45.84	0.00e+00	945.00
IUUC-Ggo-045069	Gorilla gorilla	97.18	0.00e+00	2235.00
IUUC-Hsa-046715	Homo sapiens	99.20	0.00e+00	2479.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	82.34	0.00e+00	1981.00
IUUC-Lch-050182	Latimeria chalumnae	52.89	0.00e+00	1168.00
IUUC-Loc-052705	Lepisosteus oculatus	54.47	0.00e+00	1261.00
IUUC-Laf-054132	Loxodonta africana	81.57	0.00e+00	2032.00
IUUC-Mcc-055734	Macaca mulatta	96.14	0.00e+00	2425.00
IUUC-Meu-056135	Macropus eugenii	86.70	3.00e-115	409.00
IUUC-Mga-060092	Meleagris gallopavo	63.96	0.00e+00	1523.00
IUUC-Mmr-061546	Microcebus murinus	84.81	0.00e+00	2088.00
IUUC-Mdo-061935	Monodelphis domestica	62.01	0.00e+00	1511.00
IUUC-Mmu-063630	Mus musculus	79.63	0.00e+00	1964.00
IUUC-Mpu-066579	Mustela putorius furo	80.58	0.00e+00	2023.00
IUUC-Mlu-068034	Myotis lucifugus	84.40	0.00e+00	2013.00
IUUC-Nle-069082	Nomascus leucogenys	97.48	0.00e+00	2036.00
IUUC-Opr-070953	Ochotona princeps	72.03	0.00e+00	989.00
IUUC-Ont-072435	Oreochromis niloticus	47.48	0.00e+00	1077.00
IUUC-Oan-073339	Ornithorhynchus anatinus	67.30	0.00e+00	1569.00
IUUC-Ocu-073760	Oryctolagus cuniculus	81.96	0.00e+00	2019.00
IUUC-Ola-087015	Oryzias latipes	46.92	0.00e+00	911.00
IUUC-Oga-088960	Otolemur garnettii	86.48	0.00e+00	2123.00
IUUC-Oar-089853	Ovis aries	83.84	0.00e+00	2056.00
IUUC-Pan-091962	Papio anubis	95.15	0.00e+00	2382.00
IUUC-Psi-093691	Pelodiscus sinensis	66.21	0.00e+00	1595.00
IUUC-Pma-094428	Petromyzon marinus	64.75	5.00e-91	327.00
IUUC-Pfo-096983	Poecilia formosa	47.56	0.00e+00	1014.00
IUUC-Pab-097860	Pongo abelii	97.86	0.00e+00	2263.00
IUUC-Pca-100514	Procavia capensis	79.50	0.00e+00	661.00
IUUC-Pva-102771	Pteropus vampyrus	84.23	0.00e+00	1936.00
IUUC-Rno-105405	Rattus norvegicus	78.58	0.00e+00	1912.00
IUUC-Sha-107376	Sarcophilus harrisii	64.35	0.00e+00	1480.00
IUUC-Ssc-115819	Sus scrofa	79.41	0.00e+00	1405.00
IUUC-Tgu-117262	Taeniopygia guttata	63.29	0.00e+00	1530.00
IUUC-Tru-117601	Takifugu rubripes	48.26	0.00e+00	1090.00
IUUC-Tsy-118996	Tarsius syrichta	76.95	0.00e+00	1687.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.92	0.00e+00	860.00
IUUC-Tbe-127616	Tupaia belangeri	67.31	0.00e+00	1161.00
IUUC-Ttr-129075	Tursiops truncatus	81.83	0.00e+00	1909.00
IUUC-Vpa-130108	Vicugna pacos	83.89	0.00e+00	1831.00
IUUC-Xtr-132623	Xenopus tropicalis	52.80	0.00e+00	1211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence