iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000027455.16	ENSMUST00000089140.12	ENSMUSP00000086542.6
ENSMUSG00000027455.16	ENSMUST00000028949.15	ENSMUSP00000028949.9
ENSMUSG00000027455.16	ENSMUST00000103160.4	ENSMUSP00000099449.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	miRNAMap
RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
Phospho.ELM	UniProt	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	6.90e-17	62.9	294	369

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++++qiRl+dG rlv+kF++s+++++i+ f+   +  +  + F L+++fP+++l++e++  tl+ea+L++  +++
   Q: 294  AEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVdARPAMAATSFVLMTTFPNKELADENQ--TLKEANLLNAVIVQ 369
           6889*******************************9999***********************..*********99986 PP

Organism

Mus musculus

Functional Description
(View)

Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity).

Protein Sequence
(Fasta)

MAEERQDALR EFVAVTGTEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS 60
VSRGTAPSDN RVTSFRDLIH DQDEEEEEEE GQRSRFYAGG SERSGQQIVG PPRKKSPNEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGGGCGGA GCCTACGAGC AGGCGCCCAG CGGCTGGACG CGGTAGAACG GCGGGCGGAA 60
CGCAGACCTG GGGTTCGGGC TGTTGCAGTG TCCGCCGGAG CGGTTTGGGA AGTGCACGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0446--Lipid-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

SMART

SM00553--SEP
SM00166--UBX

Gene Ontology

GO:0005694--C:chromosome
GO:0005829--C:cytosol
GO:0005795--C:Golgi stack
GO:0045111--C:intermediate filament cytoskeleton
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:1990730--C:VCP-NSFL1C complex
GO:0005543--F:phospholipid binding
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

mmu:386649

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001919	Ailuropoda melanoleuca	95.72	0.00e+00	709.00
IUUC-Atr-002543	Amborella trichopoda	30.65	7.00e-39	154.00
IUUC-Apl-003388	Anas platyrhynchos	86.35	2.00e-180	624.00
IUUC-Aca-005210	Anolis carolinensis	85.60	0.00e+00	631.00
IUUC-Aly-006329	Arabidopsis lyrata	34.17	1.00e-34	140.00
IUUC-Ago-007933	Ashbya gossypii	27.84	2.00e-18	87.00
IUUC-Afu-008919	Aspergillus fumigatus	38.66	2.00e-28	120.00
IUUC-Ani-009398	Aspergillus nidulans	30.23	3.00e-36	145.00
IUUC-Ang-009594	Aspergillus niger	28.32	1.00e-29	124.00
IUUC-Ate-010455	Aspergillus terreus	34.39	7.00e-34	138.00
IUUC-Ame-011089	Astyanax mexicanus	71.85	5.00e-148	517.00
IUUC-Bta-012898	Bos taurus	96.77	0.00e+00	717.00
IUUC-Bci-013750	Botrytis cinerea	31.97	1.00e-28	120.00
IUUC-Bdi-014746	Brachypodium distachyon	34.53	3.00e-35	142.00
IUUC-Bol-015874	Brassica oleracea	29.87	1.00e-37	150.00
IUUC-Cel-018169	Caenorhabditis elegans	40.18	2.00e-38	152.00
IUUC-Cja-018993	Callithrix jacchus	96.24	0.00e+00	718.00
IUUC-Cfa-020958	Canis familiaris	96.51	0.00e+00	717.00
IUUC-Cpo-021417	Cavia porcellus	95.70	0.00e+00	709.00
IUUC-Csa-023244	Chlorocebus sabaeus	95.70	0.00e+00	712.00
IUUC-Cho-024335	Choloepus hoffmanni	74.52	2.00e-99	355.00
IUUC-Cin-025686	Ciona intestinalis	46.99	2.00e-89	322.00
IUUC-Csv-025945	Ciona savignyi	43.54	3.00e-84	305.00
IUUC-Cne-026798	Cryptococcus neoformans	37.93	1.00e-35	144.00
IUUC-Cme-027347	Cyanidioschyzon merolae	32.25	4.00e-28	118.00
IUUC-Dre-028748	Danio rerio	70.62	1.00e-144	505.00
IUUC-Dno-029977	Dasypus novemcinctus	97.31	0.00e+00	724.00
IUUC-Dor-030203	Dipodomys ordii	96.14	0.00e+00	647.00
IUUC-Dse-031256	Dothistroma septosporum	35.32	5.00e-30	125.00
IUUC-Dme-031878	Drosophila melanogaster	44.37	1.00e-59	223.00
IUUC-Ete-032997	Echinops telfairi	95.39	0.00e+00	707.00
IUUC-Eca-034132	Equus caballus	97.34	0.00e+00	653.00
IUUC-Eeu-035097	Erinaceus europaeus	71.56	9.00e-85	306.00
IUUC-Fca-036037	Felis catus	97.05	0.00e+00	659.00
IUUC-Fal-037100	Ficedula albicollis	85.39	6.00e-172	596.00
IUUC-Fso-038190	Fusarium solani	26.53	4.00e-29	122.00
IUUC-Gmo-039429	Gadus morhua	65.50	6.00e-130	457.00
IUUC-Gga-040864	Gallus gallus	86.99	0.00e+00	647.00
IUUC-Gac-041589	Gasterosteus aculeatus	69.71	2.00e-144	505.00
IUUC-Ggo-044601	Gorilla gorilla	96.24	0.00e+00	719.00
IUUC-Hsa-045773	Homo sapiens	95.70	0.00e+00	711.00
IUUC-Itr-047949	Ictidomys tridecemlineatus	97.31	0.00e+00	727.00
IUUC-Kpa-049322	Komagataella pastoris	33.45	1.00e-29	124.00
IUUC-Lch-050608	Latimeria chalumnae	74.32	4.00e-160	557.00
IUUC-Loc-052555	Lepisosteus oculatus	73.98	5.00e-157	547.00
IUUC-Laf-054237	Loxodonta africana	96.51	0.00e+00	721.00
IUUC-Mcc-055472	Macaca mulatta	95.97	0.00e+00	718.00
IUUC-Meu-056093	Macropus eugenii	71.43	5.00e-125	440.00
IUUC-Mor-057220	Magnaporthe oryzae	25.63	6.00e-30	125.00
IUUC-Mpo-057595	Magnaporthe poae	26.24	4.00e-18	85.90
IUUC-Mla-059077	Melampsora laricipopulina	33.75	1.00e-34	141.00
IUUC-Mga-059836	Meleagris gallopavo	86.26	2.00e-171	594.00
IUUC-Mvi-060292	Microbotryum violaceum	37.70	2.00e-31	130.00
IUUC-Mmr-060897	Microcebus murinus	97.04	0.00e+00	723.00
IUUC-Mdo-062066	Monodelphis domestica	89.13	0.00e+00	668.00
IUUC-Mpu-065688	Mustela putorius furo	96.77	0.00e+00	718.00
IUUC-Mlu-067566	Myotis lucifugus	93.01	0.00e+00	671.00
IUUC-Nle-069169	Nomascus leucogenys	95.58	0.00e+00	647.00
IUUC-Opr-070979	Ochotona princeps	94.08	0.00e+00	628.00
IUUC-Ont-071803	Oreochromis niloticus	67.74	6.00e-141	493.00
IUUC-Ocu-074276	Oryctolagus cuniculus	95.98	0.00e+00	709.00
IUUC-Ola-086761	Oryzias latipes	68.92	4.00e-139	487.00
IUUC-Olu-087598	Ostreococcus lucimarinus	31.31	2.00e-31	129.00
IUUC-Oga-088533	Otolemur garnettii	96.24	0.00e+00	713.00
IUUC-Oar-089450	Ovis aries	97.04	0.00e+00	717.00
IUUC-Ptr-090926	Pan troglodytes	95.70	0.00e+00	711.00
IUUC-Pan-092100	Papio anubis	95.43	0.00e+00	710.00
IUUC-Psi-093446	Pelodiscus sinensis	85.25	2.00e-164	571.00
IUUC-Pma-094475	Petromyzon marinus	66.31	9.00e-104	369.00
IUUC-Ppa-095833	Physcomitrella patens	33.77	5.00e-34	138.00
IUUC-Pfo-096193	Poecilia formosa	69.71	9.00e-146	509.00
IUUC-Pab-097971	Pongo abelii	95.70	0.00e+00	711.00
IUUC-Pop-098970	Populus trichocarpa	33.44	6.00e-42	164.00
IUUC-Pca-100390	Procavia capensis	97.49	4.00e-131	460.00
IUUC-Pva-102504	Pteropus vampyrus	88.98	0.00e+00	652.00
IUUC-Pgr-103447	Puccinia graminis	38.34	9.00e-33	134.00
IUUC-Ptt-103729	Puccinia triticina	33.55	3.00e-36	146.00
IUUC-Rno-105448	Rattus norvegicus	99.19	0.00e+00	733.00
IUUC-Sce-106457	Saccharomyces cerevisiae	32.16	2.00e-29	123.00
IUUC-Spo-108358	Schizosaccharomyces pombe	28.64	2.00e-32	133.00
IUUC-Smo-109535	Selaginella moellendorffii	35.17	9.00e-32	130.00
IUUC-Sly-111135	Solanum lycopersicum	29.90	2.00e-39	156.00
IUUC-Stu-112733	Solanum tuberosum	33.10	3.00e-36	145.00
IUUC-Sar-113445	Sorex araneus	79.28	2.00e-131	461.00
IUUC-Sbi-114761	Sorghum bicolor	35.89	9.00e-33	134.00
IUUC-Ssc-116008	Sus scrofa	96.77	0.00e+00	716.00
IUUC-Tgu-117238	Taeniopygia guttata	86.18	0.00e+00	642.00
IUUC-Tru-118521	Takifugu rubripes	64.00	6.00e-134	470.00
IUUC-Tni-119705	Tetraodon nigroviridis	68.09	5.00e-140	490.00
IUUC-Tre-121941	Trichoderma reesei	28.54	3.00e-31	129.00
IUUC-Tvi-122602	Trichoderma virens	31.11	2.00e-27	116.00
IUUC-Tae-123686	Triticum aestivum	37.01	7.00e-37	147.00
IUUC-Tur-126267	Triticum urartu	36.82	4.00e-32	131.00
IUUC-Tme-127193	Tuber melanosporum	32.75	7.00e-39	154.00
IUUC-Tbe-127716	Tupaia belangeri	95.07	5.00e-165	573.00
IUUC-Ttr-128262	Tursiops truncatus	95.16	0.00e+00	707.00
IUUC-Uma-129600	Ustilago maydis	29.57	5.00e-39	155.00
IUUC-Vda-129743	Verticillium dahliae	29.44	2.00e-28	120.00
IUUC-Vpa-130068	Vicugna pacos	97.40	4.00e-173	600.00
IUUC-Xma-133944	Xiphophorus maculatus	69.44	6.00e-146	510.00
IUUC-Zma-135978	Zea mays	35.21	1.00e-33	136.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence