iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRTarBase	microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-08	34.0	260	297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cle+++d +l   C+H fha Cl++w           +CP+Cr
   Q: 260  CAVCLERMDDSVLAILCNHSFHARCLEQW--------ADNTCPVCR 297
           **********999999*************........8889****8 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Controls the stress response to increased levels of reactive oxygen species by modulating the brc-1-dependent expression of cki-1.

Protein Sequence
(Fasta)

MSSLYVPLVL RLEVRDRTKI VQSFIDDSKA GSESPLAGER TRQRLVKKGN TPPKKELKGR 60
EEDPPIGVMS SEPSHNYHKG RRTYSEVVIE SLDGEKLVDS SSSVAGTSEK SGGRSVSEGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTATGAGC AGTCTTTACG TGCCATTAGT TTTACGGCTC GAAGTGAGAG ACCGGACAAA 60
AATCGTGCAA TCTTTTATCG ACGACTCGAA AGCAGGAAGT GAATCCCCAC TGGCAGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0346--Stress response
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011422--BRAP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50089--ZF_RING_2
PS50271--ZF_UBP

Pfam

PF07576--BRAP2
PF13639--zf-RING_2
PF02148--zf-UBP

SMART

SM00184--RING
SM00290--ZnF_UBP

Gene Ontology

GO:0008270--F:zinc ion binding

KEGG

cel:CELE_EEED8.16

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000519	Aegilops tauschii	27.41	5.00e-40	157.00
IUUC-Aml-002229	Ailuropoda melanoleuca	37.61	6.00e-109	386.00
IUUC-Atr-002785	Amborella trichopoda	35.68	2.00e-76	278.00
IUUC-Apl-004048	Anas platyrhynchos	41.12	5.00e-107	380.00
IUUC-Aca-005133	Anolis carolinensis	40.04	1.00e-104	372.00
IUUC-Aly-006306	Arabidopsis lyrata	32.75	3.00e-64	237.00
IUUC-Ath-007604	Arabidopsis thaliana	32.61	2.00e-66	245.00
IUUC-Ago-007905	Ashbya gossypii	31.75	2.00e-60	225.00
IUUC-Acl-008310	Aspergillus clavatus	32.04	7.00e-60	223.00
IUUC-Afl-008497	Aspergillus flavus	31.66	8.00e-52	196.00
IUUC-Afu-008830	Aspergillus fumigatus	35.17	1.00e-57	216.00
IUUC-Ani-009485	Aspergillus nidulans	31.86	5.00e-62	230.00
IUUC-Ang-009603	Aspergillus niger	33.33	2.00e-57	215.00
IUUC-Aor-009935	Aspergillus oryzae	30.57	4.00e-56	211.00
IUUC-Ate-010485	Aspergillus terreus	34.30	3.00e-62	231.00
IUUC-Ame-011516	Astyanax mexicanus	40.38	1.00e-91	328.00
IUUC-Bgr-011985	Blumeria graminis	28.87	2.00e-49	189.00
IUUC-Bta-013203	Bos taurus	37.88	5.00e-110	390.00
IUUC-Bci-013788	Botrytis cinerea	37.07	7.00e-57	214.00
IUUC-Bdi-014763	Brachypodium distachyon	33.89	1.00e-69	256.00
IUUC-Bol-015518	Brassica oleracea	31.53	4.00e-65	241.00
IUUC-Bra-017435	Brassica rapa	31.12	1.00e-65	242.00
IUUC-Cja-018948	Callithrix jacchus	36.44	2.00e-107	381.00
IUUC-Cfa-020377	Canis familiaris	37.16	2.00e-109	388.00
IUUC-Cpo-021930	Cavia porcellus	36.21	8.00e-107	379.00
IUUC-Cre-022571	Chlamydomonas reinhardtii	36.75	4.00e-47	180.00
IUUC-Csa-023554	Chlorocebus sabaeus	37.25	8.00e-96	342.00
IUUC-Cho-025045	Choloepus hoffmanni	31.66	5.00e-29	121.00
IUUC-Cin-025326	Ciona intestinalis	38.54	3.00e-87	314.00
IUUC-Csv-026232	Ciona savignyi	39.02	2.00e-89	321.00
IUUC-Cgl-026587	Colletotrichum gloeosporioides	32.82	3.00e-64	238.00
IUUC-Cne-026980	Cryptococcus neoformans	29.93	2.00e-39	155.00
IUUC-Cme-027262	Cyanidioschyzon merolae	30.69	4.00e-52	198.00
IUUC-Dre-028521	Danio rerio	36.28	6.00e-103	366.00
IUUC-Dno-029291	Dasypus novemcinctus	36.53	4.00e-105	374.00
IUUC-Dor-030231	Dipodomys ordii	33.50	2.00e-92	331.00
IUUC-Dse-031234	Dothistroma septosporum	29.43	5.00e-50	191.00
IUUC-Dme-032095	Drosophila melanogaster	36.18	5.00e-94	337.00
IUUC-Ete-032227	Echinops telfairi	34.47	5.00e-63	234.00
IUUC-Eca-034404	Equus caballus	37.04	3.00e-109	387.00
IUUC-Eeu-035030	Erinaceus europaeus	41.63	9.00e-40	156.00
IUUC-Fca-035428	Felis catus	37.31	2.00e-108	385.00
IUUC-Fal-037435	Ficedula albicollis	39.81	1.00e-107	382.00
IUUC-Fox-037733	Fusarium oxysporum	29.93	6.00e-57	214.00
IUUC-Fso-038427	Fusarium solani	32.51	2.00e-55	209.00
IUUC-Gmo-038817	Gadus morhua	39.06	2.00e-100	358.00
IUUC-Ggr-039949	Gaeumannomyces graminis	30.97	1.00e-55	210.00
IUUC-Gga-040929	Gallus gallus	39.69	7.00e-109	386.00
IUUC-Gac-041893	Gasterosteus aculeatus	36.15	1.00e-100	358.00
IUUC-Gma-043119	Glycine max	31.72	8.00e-68	249.00
IUUC-Ggo-045106	Gorilla gorilla	39.86	3.00e-93	334.00
IUUC-Hsa-045685	Homo sapiens	36.99	2.00e-110	392.00
IUUC-Hvu-047475	Hordeum vulgare	31.65	2.00e-34	137.00
IUUC-Itr-048406	Ictidomys tridecemlineatus	36.72	2.00e-107	381.00
IUUC-Kpa-049175	Komagataella pastoris	33.18	4.00e-63	234.00
IUUC-Lch-050408	Latimeria chalumnae	38.30	5.00e-106	377.00
IUUC-Lpe-050777	Leersia perrieri	31.67	1.00e-58	219.00
IUUC-Loc-052160	Lepisosteus oculatus	30.70	3.00e-67	248.00
IUUC-Lma-053095	Leptosphaeria maculans	32.54	1.00e-66	246.00
IUUC-Laf-053497	Loxodonta africana	37.54	1.00e-107	382.00
IUUC-Mcc-055381	Macaca mulatta	37.16	1.00e-110	392.00
IUUC-Meu-056402	Macropus eugenii	33.33	1.00e-52	199.00
IUUC-Mor-057002	Magnaporthe oryzae	33.19	1.00e-61	229.00
IUUC-Mpo-057508	Magnaporthe poae	35.00	2.00e-52	199.00
IUUC-Mtr-058619	Medicago truncatula	33.18	2.00e-60	225.00
IUUC-Mla-058901	Melampsora laricipopulina	41.67	3.00e-57	215.00
IUUC-Mga-059667	Meleagris gallopavo	42.31	6.00e-107	379.00
IUUC-Mvi-060229	Microbotryum violaceum	28.67	1.00e-52	199.00
IUUC-Mmr-060881	Microcebus murinus	35.79	5.00e-97	347.00
IUUC-Mdo-062573	Monodelphis domestica	36.22	3.00e-102	364.00
IUUC-Mmu-063656	Mus musculus	36.90	3.00e-110	390.00
IUUC-Mac-065512	Musa acuminata	34.71	4.00e-73	267.00
IUUC-Mpu-065816	Mustela putorius furo	37.16	1.00e-108	385.00
IUUC-Mlu-067225	Myotis lucifugus	37.50	2.00e-109	388.00
IUUC-Nfi-068534	Neosartorya fischeri	35.17	9.00e-58	217.00
IUUC-Ncr-068801	Neurospora crassa	29.15	4.00e-59	221.00
IUUC-Nle-069258	Nomascus leucogenys	38.16	1.00e-105	375.00
IUUC-Opr-070877	Ochotona princeps	39.79	3.00e-97	347.00
IUUC-Ont-072141	Oreochromis niloticus	35.51	7.00e-100	356.00
IUUC-Oan-072961	Ornithorhynchus anatinus	38.01	8.00e-107	379.00
IUUC-Ocu-074020	Oryctolagus cuniculus	38.74	6.00e-96	345.00
IUUC-Oba-075084	Oryza barthii	28.85	6.00e-57	213.00
IUUC-Obr-076840	Oryza brachyantha	34.66	1.00e-69	255.00
IUUC-Ogl-077880	Oryza glaberrima	34.90	7.00e-65	239.00
IUUC-Ogu-078968	Oryza glumaepatula	28.66	8.00e-57	213.00
IUUC-Oin-079200	Oryza indica	34.90	8.00e-65	239.00
IUUC-Olo-080753	Oryza longistaminata	30.81	1.00e-53	202.00
IUUC-Ome-081756	Oryza meridionalis	30.70	1.00e-56	213.00
IUUC-Oni-082434	Oryza nivara	28.54	5.00e-57	214.00
IUUC-Opu-083262	Oryza punctata	30.94	4.00e-57	214.00
IUUC-Oru-084381	Oryza rufipogon	28.66	8.00e-57	213.00
IUUC-Osa-085760	Oryza sativa	40.44	7.00e-55	206.00
IUUC-Ola-087390	Oryzias latipes	36.74	1.00e-96	345.00
IUUC-Olu-087694	Ostreococcus lucimarinus	29.06	9.00e-55	206.00
IUUC-Oga-088612	Otolemur garnettii	37.52	3.00e-109	387.00
IUUC-Oar-089988	Ovis aries	37.27	2.00e-107	382.00
IUUC-Ptr-090637	Pan troglodytes	36.99	3.00e-110	391.00
IUUC-Pan-092506	Papio anubis	37.16	1.00e-110	392.00
IUUC-Psi-093026	Pelodiscus sinensis	38.86	9.00e-102	362.00
IUUC-Pno-094779	Phaeosphaeria nodorum	28.34	2.00e-43	168.00
IUUC-Ppa-095731	Physcomitrella patens	34.28	5.00e-75	273.00
IUUC-Pfo-096725	Poecilia formosa	36.05	2.00e-96	345.00
IUUC-Pab-098413	Pongo abelii	42.11	7.00e-84	303.00
IUUC-Pop-099538	Populus trichocarpa	32.48	1.00e-65	242.00
IUUC-Pca-100130	Procavia capensis	42.47	5.00e-83	300.00
IUUC-Ppe-101843	Prunus persica	32.76	4.00e-72	263.00
IUUC-Pva-102752	Pteropus vampyrus	40.32	3.00e-106	377.00
IUUC-Pgr-103478	Puccinia graminis	34.42	2.00e-61	229.00
IUUC-Ptt-103921	Puccinia triticina	36.27	3.00e-60	225.00
IUUC-Pte-104032	Pyrenophora teres	31.91	2.00e-62	232.00
IUUC-Pyt-104480	Pyrenophora triticirepentis	31.71	9.00e-62	230.00
IUUC-Rno-106037	Rattus norvegicus	35.36	5.00e-85	307.00
IUUC-Sce-106310	Saccharomyces cerevisiae	29.18	2.00e-49	188.00
IUUC-Sha-106752	Sarcophilus harrisii	38.80	9.00e-105	372.00
IUUC-Sja-107665	Schizosaccharomyces japonicus	33.18	8.00e-68	249.00
IUUC-Spo-108042	Schizosaccharomyces pombe	34.64	5.00e-64	237.00
IUUC-Ssl-108504	Sclerotinia sclerotiorum	34.99	8.00e-57	214.00
IUUC-Smo-109399	Selaginella moellendorffii	34.60	7.00e-75	273.00
IUUC-Sit-110251	Setaria italica	33.91	8.00e-70	256.00
IUUC-Sly-111563	Solanum lycopersicum	34.23	9.00e-66	242.00
IUUC-Stu-112294	Solanum tuberosum	34.92	4.00e-71	260.00
IUUC-Sar-113080	Sorex araneus	56.44	2.00e-36	144.00
IUUC-Sbi-113915	Sorghum bicolor	34.06	1.00e-68	252.00
IUUC-Sre-114897	Sporisorium reilianum	36.18	2.00e-53	202.00
IUUC-Ssc-115369	Sus scrofa	56.90	8.00e-60	221.00
IUUC-Tgu-116710	Taeniopygia guttata	39.96	5.00e-110	390.00
IUUC-Tru-117941	Takifugu rubripes	35.08	3.00e-102	364.00
IUUC-Tsy-118902	Tarsius syrichta	37.26	1.00e-41	162.00
IUUC-Tni-120587	Tetraodon nigroviridis	35.92	4.00e-104	370.00
IUUC-Tca-121425	Theobroma cacao	33.33	1.00e-69	256.00
IUUC-Tre-121874	Trichoderma reesei	31.02	3.00e-59	221.00
IUUC-Tvi-122266	Trichoderma virens	36.60	5.00e-57	214.00
IUUC-Tae-124194	Triticum aestivum	34.78	2.00e-66	245.00
IUUC-Tur-126467	Triticum urartu	32.65	6.00e-45	173.00
IUUC-Tme-127096	Tuber melanosporum	33.20	6.00e-57	213.00
IUUC-Tbe-128012	Tupaia belangeri	40.38	4.00e-97	347.00
IUUC-Ttr-128388	Tursiops truncatus	37.16	5.00e-108	383.00
IUUC-Uma-129610	Ustilago maydis	27.94	1.00e-51	197.00
IUUC-Vda-129830	Verticillium dahliae	29.74	1.00e-59	223.00
IUUC-Vpa-130171	Vicugna pacos	37.90	7.00e-110	389.00
IUUC-Vvi-131063	Vitis vinifera	38.74	9.00e-65	239.00
IUUC-Xtr-132313	Xenopus tropicalis	39.42	2.00e-106	378.00
IUUC-Xma-133303	Xiphophorus maculatus	36.22	4.00e-97	347.00
IUUC-Yli-134669	Yarrowia lipolytica	31.78	1.00e-56	212.00
IUUC-Zma-135783	Zea mays	34.28	5.00e-68	250.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence